Most Votes
- By the end of 2026, how useful do you think agentic/multi-agent AI systems will actually be in your daily work or personal projects? Posted on March 11th, 2026 | 12772 votes
Most Comments
- By the end of 2026, how useful do you think agentic/multi-agent AI systems will actually be in your daily work or personal projects? Posted on March 11th, 2026 | 40 comments
what do they do? (Score:2)
btw, frist psot
Re:what do they do? (Score:5, Informative)
Acetylcholine is the base chemical that almost all the neurotransmitters are made from. NT's are what makes the brain function
Adrenaline makes you ready to fight or run. Accelerates your body
Dopamine is the pleasure transmitter I believe, or its a pain blocker. Gives your body the positive reward response. Cocaine's high is from exciting dopamine receptors
Endorphine is similar to dopamine, I think one of them is a pain blocker and the other is a reward.
Serotonin gives you your good mood. Ectacy users know all about this, that is what E does, it boost your seritonin levels through the roof.
Oxycotin, isn't a NT as far as I know, its a synthetic opiate. effects endorphine receptors?
Histamines I don't know how to describe, but allergic reactions release histamines in your body, that is the reaction.
Insulin, isn't an NT either, it burns sugar in your body.
Re:what do they do? (Score:5, Informative)
Re:what do they do? (Score:4, Informative)
Re:what do they do? (Score:2)
Re:what do they do? (Score:5, Funny)
Oxytocin is good stuff. Without it my post-baby belly would never disappear!
Re:what do they do? (Score:5, Funny)
First words (Score:5, Funny)
"Push the button, Frank."
We told Trace Beaulieu about this at a convention a few years ago, and he turned to her and said with a voice of sympathy "I'm very sorry."
Oxytocin Not Oxycotin. (Score:4, Informative)
Re:Oxytocin Not Oxycotin. (Score:5, Funny)
Some kids broke into a vet's office looking for the pain blocker and ended up with the hormone instead. Considering it induces breastfeeding responses, even in men, the results were rather humrous.
Re:Oxytocin Not Oxycotin. (Score:2, Informative)
-Peter
Re:Oxytocin Not Oxycotin. (Score:4, Funny)
*hangs his head*
And my wife doesn't understand why I want to move from such a wonderful suburb of Noblesville to some place a little higher on the educational ladder. Say .... Kentucky, or Arkansas.
Re:Oxytocin Not Oxycotin. (Score:2, Informative)
Actually the drug is Oxycontin
Actually... (Score:4, Interesting)
The drug labeling information with all the technical stuff may be found here [fda.gov].
Re:Oxytocin Not Oxycotin. (Score:4, Insightful)
Gee, seems pretty coincidental that it's a drug usually given to people... WHO ARE TERMINALLY ILL! Would you rather die flipped out of your mind on drugs or live an extra month in unbearable pain from an untreatable disease that's eating you alive?
And really, what a bunch of sensationalist tripe. 500 people... 500 PEOPLE . Less than two ten-thousandths of one percent of the U.S. population. Not exactly a leading cause of death. Nor would that be considered "many."
As an aside, the people who run that site act like each name reported comes from a desperate loved one of that person trying to "fight for the cause"... yet 80% of the one-liners are nearly IDENTICAL. They just googled for obituaries & news reports to get a long list of names.
Re:oxytocin (Score:3, Interesting)
Plus, the dosage of Pitocin is often much higher than oxytocin l
Re:oxytocin (Score:3, Interesting)
Probably the same doctor I had a few years back who was trying to write me a prescription for Penicillin while using my medical folder for a writing surface. A folder with a 4x4 inch red and white "ALLERGIC TO PENICILLIN" sticker on the front. No, the prescription pad wasn't covering the sticker, it was in plain sight. When I pointed it out to him (quite nicely I thought) he actually had the nerve to question whether I was really allergic or not. H
Re:what do they do? (Score:2, Informative)
i mean - sure, testostorone can regulate some processes, but it isnt a neurotransmitter.
i (as a former biochemist) call bs on this entire poll
Re:what do they do? (Score:4, Informative)
Acetylcholine [wikipedia.org]
Adrenaline [wikipedia.org]
Dopamine [wikipedia.org]
Endorphine [wikipedia.org]
Serotonin [wikipedia.org]
Oxytocin [wikipedia.org]
Histamines [wikipedia.org]
Insulin [wikipedia.org]
And this is some text for the lameness filter.
And this is some text for the lameness filter.
And this is some text for the lameness filter.
And this is some text for the lameness filter.
Re:what do they do? (Score:3, Interesting)
(Side note: Histamine and insulin are not neurotransmitters.)
Acetylcholine: What makes your enemies' muscles convulse so strongly they break their own bones to shreds when you hit 'em with acetylcholinesterase inhibitors. (Or when you nail those goddamn roaches with the bug spray, which is pretty much same thing.)
Adrenaline: What you secrete when you're trying to figure out what to do about the simultaneous appearance of a cloud of dense fog coming towards y
Seratonin? (Score:3, Funny)
Re:what do they do? (Score:3, Informative)
Why bother? Someone has already done it. [wikipedia.org]
Re:what do they do? (Score:5, Informative)
For this list:
Acetylcholine: The primary neurotransmitter of the parasympathetic nervous system- in other words, it transmits signals other than fight-or-flight type, and is necessary for normal cognitive function.
Adrenaline: Synthesized from the amino acid tyrosine, and released from the adrenal medulla, this NT takes care of sympathetic responses, the fight-or-flight stuff that jacks up your heart rate and mobilizes the body for action. Also known as epinephrine.
Dopamine: A few steps up in the synthesis ladder for adrenaline is this NT, which is involved in the brain's "reward system" and also in motor control- dopaminergic neurons are damaged in Parkinson's disease, leading to its characteristics.
Endorphin: Actually a group of compounds, endorphins are, as their name suggests, endogenous opioids, and are released in respone to pain. Responsible for "runner's high."
Serotonin: Also known as 5-HT, this neurotransmitter can have a powerful effect on mood and behavior. Antidepressants known as MAOIs inhibit the action of the enzyme monoamine oxidase which breaks serotonin down.
Oxytocin: A peptide hormone released by the pitutary gland, oxytocin is sometimes known as "the love hormone," because it is released during many mating/parental bonding type events.
Histamine: A substance made from the amino acid histidine, it helps regulate stomach acid secretion (it's one of the H's in H2 blocker drugs), but it better known for the powerful inflammatory response it causes in allergic reactions.
Insulin: Peptide hormone released by the pancreas in response to increased blodd glucose levels; has a variety of effects dealing with metabolism and energy use.
I know I'm not supposed to complain about poll options, but the poll leaves out some of my favorite NTs, like ATP, GABA, norepinephrine, and nitric oxide.
Re:what do they do? (Score:2)
Re:what do they do? (Score:2)
When I was hit by a car 2 years ago I didn't feel any pain for several minutes, despite having one hand dislocated off the end of my arm (which was also broken).
Re:what do they do? (Score:4, Informative)
And of course, our favorite exogenous opiates of heroin, morphine, and opium have the same effect because they act on the same receptors!
Also, Prozac, Paxil, and Zoloft are reuptake inhibitors for serotonin, meaning that they cause the seratonin to be reabsorbed more slowly and make more of it available for neurotransmission. These antidepressants are thus known as serotonin-specific reuptake inhibitors, or SSRIs.
Re:what do they do? (Score:3, Interesting)
Don't forget glutamate, the major excitatory neurotransmitter in the CNS. My personal favorite NT is anandamide, which binds to the cannabinoid receptor and is one of the first known retrograde neurotransmitters.
Re:what do they do? (Score:3, Interesting)
Endorphins... (Score:2)
What about.... (Score:5, Funny)
Re:What about.... (Score:5, Funny)
Re:What about.... (Score:5, Funny)
A crummy commercial??? Damn you slashdot!
Obligitory Bania (Score:5, Funny)
missing option.... (Score:2)
Re:missing option.... ANANDAMIDE (Score:2, Informative)
insulin... (Score:2)
http://faculty.washington.edu/chudler/chnt1.html
here's what they do.... (Score:5, Informative)
Adrenaline - fight or flight hormone, gets the body revved up to go.
Dopamine - multi system regulation (heart, kidneys, brain, etc)
Endorphin - opiod like chemical produced in brain...makes you feel good.
Serotonin - modulates mood, sleep and emotion. Target for antidepressant meds.
Oxytocin - causes milk "drop down" in breast feeding and mediates the labor process
Histamine - causes the itching from an allergic reaction
Insulin - controls uptake of sugar from the blood. No insulin = diabetes.
Re:here's what they do.... (Score:5, Funny)
None of you know what to vote for, but the nice guy in the parent comment helped out by explaining the options. To save you even more time reading:
VOTE OXYTOCIN! IT INVOLVES BOOBIES!
Re:here's what they do.... (Score:3, Funny)
So you're saying it puts men to sleep?
Re:here's what they do.... (Score:2)
If I was born with more of it, I wouldn't feel like shit most of the time. In other words, I have depression.
After that I would pick Endorphin. Endorphins are fun
Dopamine (AFAIK) does more than system regulation. Its attributed to mental illnesses like schizophrenia.
Histamine is not a neurotransmitter. Its just a chemical that goes crazy with allergies. When that happens, grab
Re:here's what they do.... (Score:3, Interesting)
Maybe thats why LSD my favorite drug.
I've found it interesting that the molecules of serotonin, psilocybin, mescaline, and LSD (less so), have similar chemical structures as seen here [bris.ac.uk]. What's also weird, is that these drugs are not what I call "feel good" drugs. They are psychedelics that are very tripped out, but I would not consider them antidepressants or anything like
Re:here's what they do.... (Score:3, Interesting)
I've only done MDMA once, and I was also on 4 other drugs (weak LSD, alcohol, some mushrooms, & pot) so I can't isolate the effects totally, but I didn't care for it that much. I sweated profusely and felt speed up and "good". The majority of the high was from MDMA. It didn't seem to last that long. I did the "pure" powder form of MDMA often called "molly". YMMV.
Speaki
Re:here's what they do.... (Score:5, Funny)
Same here. I also want pain-and-suffering damages related to the mental image I now have of Rush Limbaugh breastfeeding a newborn baby.
Endorphins and Sex, BABY! (Score:2)
I realize that slashdot readers might not be in this situation, but I'm sure your right (or left) hand may be sufficient for you to maximize your endorphin, uhhh, loading.
Great cure for headaches, too...
Serotonin, anyone? (Score:5, Funny)
Endorphin (Score:4, Insightful)
Re:Endorphin (Score:2)
I guess I'll have to fall back on the chocolate option...
What about (Score:3, Funny)
Endorphin Rush (Score:2)
Insulin (Score:5, Insightful)
Dopamine (Score:2, Funny)
Re:Insulin (Score:3, Insightful)
I vote for telepathy... (Score:2)
endorphin is not a single neurotransmitter. (Score:5, Informative)
Mmmm... morphine.
Re:endorphin is not a single neurotransmitter. (Score:2)
Oxytocin (Score:2)
Whichever one stops this pain... (Score:2, Informative)
My swim coach taught me that... (Score:2)
Re:My swim coach taught me that... (Score:2)
That's because bananas are a good source of Potassium; lack of potassium and other electrolytes is the main cause of muscle cramps, not anything to do with neurotransmitters. Gatorade, vitamin pills do the same thing.
Re:My swim coach taught me that... (Score:2)
There was nothing worse that being half way down your lane and getting a cramp so bad you leg would bend all the way back and someone had to help you back the wall.
Re:My swim coach taught me that... (Score:3, Funny)
I can't stop voting for Endorphin (Score:5, Funny)
[back]
[Vote]
[back]
[Vote]
Feels good though.
[back]
[Vote]
[back]
[Vote]
Hmm, Adrenaline?
[back]
[Vote]
[back]
[Vote]
[back]
[Vote]
[Vote]
[back]
[Vote]
[back]
[Vote]
Yes, that helped.
Serotonin (Score:2)
Not nice.
Re:Serotonin (Score:2)
Re:Serotonin (Score:3, Informative)
Re:Serotonin (Score:2)
Perhaps that's what I was thinking of. HBO used to run a series called "Autopsy." Not too cheery, I'll admit, but I one point they were analyzing the seratonin levels in the brains of people that had killed themselves. Apparently the levels were through the roof.
My least favorite one is Insulin.... (Score:2)
I'm no biologist, but lately I've done a lot of reading up on weight loss techniques, and even tried (successfully) some of them. It turns out that in addition to lowering blood glucose levels, Insulin also triggers storage of dietary fat as body fat. This second property of Insulin (the first one is lowering blood sugar) is very often ignored/overlooked.
It's somethi
what about... (Score:2)
'nuf said. All this talking made me thirsty
Can't decide! (Score:5, Funny)
Missing options... (Score:2)
GABA (gamma-aminobutyric acid): An inhibitory neurotransmitter that regulates Cl- and K+ cellular ion channels. In the brain, GABA works in the hippocampus and affects memory. The anxiolytic benzodiazepines (minor tranquilizers used in treating anxiety disorders) - including such drugs as diazepam (Valium), lorazepam (Ativan), clonazepam (Klonopin), flunitrazepam (Ro
You insensitive clod! (Score:2)
Save the dolphins! (Score:3, Funny)
Acetylcholine and Organophosphates (Score:3, Interesting)
Anti-Histamine! (Score:2)
Re:Anti-Histamine! Defending histamines a bit (Score:2)
Caffeine? (Score:2, Funny)
As shamelessly stolen from a nameless Farker: "Coffee is good. If you don't make more coffee we'll kill this dog."
Neurotransmitters (Score:5, Informative)
Adrenaline - AKA epinephrine, primary involved in stress response and autonomic regulation of blood vessel tone and heart rate, also produced in adrenal glands for stress hormonal response, and your doctor's favorite drug of use emergency treatment of low blood pressure and ventricular fibrillation.
Dopamine - another catecholamine type neurotransmitter, involved in autonomic blood pressure regulation, low dose increase blood flow to kidney, wheras high dose will increase vascular tone and heart contractility.
Endorphine - a polypeptide neurotransmitter, involved in pain transmission and actually blocks transmission of pain signals to the brain. Also results in mild vasodilatation.
Serotonin - AKA 5-hydroxy-tryptamine, mostly found in central nervous transmission in brain, and involved in mood regulation; the theory goes low levels of serontonin activity results in depression. High levels can also lead to hallucinations as in LSD - a serotonin analogs. Most modern antidepressant drug, e.g. Prozac, Celexa, Sertraline, slow down the uptake of serotonin neurotransmitter from synaptic cleft to effectively raise serotonin levels.
Oxytocin - another polypeptic neurotransmitter, involved in neurotransmission of lactation - production of milk in mammary glands.
Histamine - not a catecholamine nor a polypeptide molecule. Involved in allergic response as in hayfever and asthma. Also involved in the gut nervous system in stimulating the production of hydrochloric acid in stomach causing heartburn, ulcers and aiding digestion of proteins.
Insulin - not really a neurotransmitter, mostly a hormone, produced in the beta islet cells of the pancreas and involved in the regulation of glucose uptake, production and storage. Lack of insulin production leads to Type I Diabetes mellitus, whereas Insulin resistance as in obesity leads to Type II Diabetes Mellitus. May also insulin receptors in brain regulating hunger. Counter-regulatory hormones include glucagon and growth hormone.
Re:Neurotransmitters (Score:3, Informative)
Not sure if parent's quote is accurate or not (IANAD), however I do know that LSD (and related psychadelics) do not cause hallucinations by raising the Serotonin level - what they do is mimic the chemcial structure of Serotonin, so receptors where it normally bonds to it cannot since LSD/Psilocybin/etc are taking it's place.
Now Serotonin is a deactivating neutrotransmitter, meaning it slows/stops the progression of chemical sign
Serotonin (Score:2)
It also REALLY helps reduce the impact of serotonin depletion on your mood if you take ecstasy, take a couple of 5-HTP on your comedown and the "downer" is almost complet
Instead of Oxytocin... (Score:2)
Interesting. (Score:2)
No contest! (Score:3, Informative)
"Although the effect of psychotropic drugs on various hormones is not certain, their effect on several neurotransmitters influencing sexual function is well established. Dopamine is the neurotransmitter in the mesolimbic "pleasure center." Increasing dopaminergic activity may enhance sexual response, and blocking it may compromise response."
I'd call that a winner, folks.
Re:No contest! (Score:2)
Dopamine. Yea, definitely dopamine [biopsychiatry.com].
With seratonin [biopsychiatry.com] as a close second.
Please respond, Business Plan in the works (Score:2)
Oxy (Score:3, Funny)
Missing Option (Score:2)
There's a popular one missing (Score:5, Funny)
Re:There's a popular one missing (Score:3, Insightful)
Glutamate and GABA? (Score:3, Informative)
And, why yes. I am a neuroscientist.
DMT (Score:2)
A missing tryptamine (Score:5, Interesting)
Re:A missing tryptamine (Score:5, Informative)
Poll options badly mangled (from the poll author) (Score:3, Interesting)
I had instead NO (nitrous oxide) - the controversial one - and the CowboyNeal option "My nervous system is purely electrical". Why they had messed up with my poll is beyond me.
Re:Neurotoxin (Score:2)
Agent Orange
McDonalds
Television
Perchlorate
Let's leave this planet, and go somewhere else more fun with less restrictions and fear. Who's with me?
Re:Neurotoxin (Score:2)
ethanol.
Re:Beer? (Score:2)
ObClavin (Score:5, Funny)
But in the immortal words of Cliff Clavin:
Re:ObClavin (Score:5, Funny)
Re:Beer? (Score:2)
What's your favorite neurotoxin?
Re:Dopamine (Score:2)