Comment Not a useful question atm (Score 2) 21
There seem to be three standard rules.
1. Anything that is not demonstrably impossible is technically possible.
2. Within the set of what is technically possible, we need only look at the subset of simplest explanations.
3. Within the subset of simplest explanations, we need only consider those for which the level of evidence equals or exceeds the improbability of correctness.
A brain microbiome is technically possible, but it is not in the subset of simplest explanations, nor is the level of evidence sufficient. As such, It fails both the second and third tests.
To me, this does not mean we reject it outright, it means we simply don't consider it at all for right now. We neither accept nor reject, we simply put it to one side and see what scientists find in future. It's not a model we can usefully explore or make predictions with that would permit falsification.
Scientists are finding all kinds of new communications channels and behaviours within the brain. Clearly, our knowledge is nowhere near adequate to determine what is required. Let's get that sorted first, and then decide if there is anything left that needs a microbiome explanation.