Easiest way to tackle 'a' drone in a combat situation is with another semi-automated drone. Rather than carrying weighty explosive, simply a somewhat armoured drone with steel blades, basically a flying lawnmower (said drone could also target people, flying buzz saw, quite nasty). Set if off in the general direction and let it use sonar for the final attack run, some times it will survive and sometimes it will not but the targeted drone will go down (lighter fabrication due to payload and required range). Many boomerang drones at once, far more problematic (boomerang because they come back for reuse if they do not strike a desired target and detonate).
Tackling 'a' boomerang drone in any more modern battle field will be totally unrealistic, as sending out say, 10 times as many as required to complete target destruction, to ensure some get through would be the norm, what the heck, you can bring back say 60% to 80% of them and automatically disarm them and send them out again, once they have been rearmed.
Being a combatant on a drone dominated battlefield means nothing but being a short life target, praying they run out of drones before you do, with the defending side having a great advantage in that regard ie defence structures housing tens of thousands of drones (relatively safe whilst they are locked up inside and indescribably dangerous when released all at once, why not, if you win, you can automatically recover all drones that failed to achieve their targets and were not destroyed).
They whole idea is to stop playing war by ensuring psychopaths no longer gain positions of governance or influence, rather than coming up with more and more stupid ways of killing each other.