Submission + - Well, shit.
Cpt_Kirks writes: Patrick Stewart dead at 86.
Comment Now for the serious post... amend the title (Score 4, Insightful) 155
I would amend the title to: "Please let the way that most people use the internet die".
And that has to start with individuals.
Are you ready to give up social media and clutivate a local group of like-minded friends who will put in the time and effort to socialize in-person?
Are you ready to shop locally for everything you can, and not order online unless you have to?
Are you ready to walk or drive yourself to your favorite local restaurant to pick up your takeout, instead of using a gig delivery service?
Are you ready to eschew LLMs, even to the point of pushing back on your employer if they insist you incorporate LLM output in your work?
The punchline to my little ol' rant here is that I feel most people are too comfortable with, or too addicted to, or whatever to, the kind of things I mention above, and that for most people, if they think about it at all, might have a passing thought of "why should I bother, some other activist will start the fight and then I'll just like their posts".
Comment I'm gonna go build my own internet! (Score 1) 155
With blackjack! And hookers!
Submission + - Bank of America kindly asks that you don't share your password with your AI asst (techcrunch.com)
schwit1 writes: In an email blast to customers titled “Protecting your finances in the Al World,” Bank of America urged customers to never share their username and password with another person or an outside service, “including an Al-enabled tool or agent that offers to act on your behalf.”
You can practically sense the frustration in the person sending the email. Still, customers are increasingly handing over their log-ins as personal AI assistants grow more popular. Sharing your banking username and password with an AI assistant runs the risk that it could do something with your finances without your knowledge, or that your bank thinks someone’s raiding your account and locks you out of it. Worse, a security flaw in the AI assistant could result in it leaking your banking credentials elsewhere, giving financially motivated hackers a way into your bank account.
You can practically sense the frustration in the person sending the email. Still, customers are increasingly handing over their log-ins as personal AI assistants grow more popular. Sharing your banking username and password with an AI assistant runs the risk that it could do something with your finances without your knowledge, or that your bank thinks someone’s raiding your account and locks you out of it. Worse, a security flaw in the AI assistant could result in it leaking your banking credentials elsewhere, giving financially motivated hackers a way into your bank account.
Submission + - This frog bacterium wiped out cancer tumors in mice with a single dose (sciencedaily.com)
fahrbot-bot writes: Science Daily has reported that scientists at the Japan Advanced Institute of Science and Technology (JAIST) have identified a naturally occurring bacterium from the intestines of Japanese tree frogs (Dryophytes japonicus) that demonstrated remarkable anticancer activity in mice. The findings, published in Gut Microbes, introduce a new approach to cancer treatment that uses living bacteria to directly target tumors rather than simply altering the gut microbiome.
In a mouse model of colorectal cancer, a single intravenous dose of E. americana completely eliminated tumors, producing a 100% complete response (CR) rate. The researchers emphasize that these findings are limited to mice, but they believe the results provide an encouraging proof of concept for developing new bacterial cancer therapies.
First, E. americana directly attacks tumors. As a facultative anaerobic bacterium, it thrives in both oxygen rich and oxygen poor environments, allowing it to multiply inside the oxygen deprived regions commonly found within tumors. Once there, the bacterial population increased by roughly 3,000 fold within 24 hours after treatment, directly damaging cancer cells.
Second, the bacterium stimulates the immune system. Its presence attracted T cells, B cells, and neutrophils into tumors. These immune cells then released inflammatory signaling molecules, including TNF- and IFN-, which strengthened the immune response and promoted cancer cell death.
One of the most striking findings was that E. americana accumulated almost exclusively inside tumors and did not colonize healthy organs.
They found that the bacteria were rapidly cleared from the bloodstream, with a half life of approximately 1.2 hours, and became undetectable within 24 hours. No bacterial colonization was detected in healthy organs, including the liver, spleen, lungs, kidneys, or heart.
The treatment caused only mild, temporary inflammation that returned to normal within 72 hours. During a 60 day observation period, the researchers found no evidence of chronic toxicity.
In a mouse model of colorectal cancer, a single intravenous dose of E. americana completely eliminated tumors, producing a 100% complete response (CR) rate. The researchers emphasize that these findings are limited to mice, but they believe the results provide an encouraging proof of concept for developing new bacterial cancer therapies.
First, E. americana directly attacks tumors. As a facultative anaerobic bacterium, it thrives in both oxygen rich and oxygen poor environments, allowing it to multiply inside the oxygen deprived regions commonly found within tumors. Once there, the bacterial population increased by roughly 3,000 fold within 24 hours after treatment, directly damaging cancer cells.
Second, the bacterium stimulates the immune system. Its presence attracted T cells, B cells, and neutrophils into tumors. These immune cells then released inflammatory signaling molecules, including TNF- and IFN-, which strengthened the immune response and promoted cancer cell death.
One of the most striking findings was that E. americana accumulated almost exclusively inside tumors and did not colonize healthy organs.
They found that the bacteria were rapidly cleared from the bloodstream, with a half life of approximately 1.2 hours, and became undetectable within 24 hours. No bacterial colonization was detected in healthy organs, including the liver, spleen, lungs, kidneys, or heart.
The treatment caused only mild, temporary inflammation that returned to normal within 72 hours. During a 60 day observation period, the researchers found no evidence of chronic toxicity.
Submission + - Blue Chip - fully US supply chain laptop (anduril.com)
fadethepolice writes: Anduril, arguing that its manuftacuring capabilities are directly applicable to laptop manufacturing is starting a project for a fully 100 percent US sourced laptop. The computer will use a Qualcomm snapdragon SOC. I did not see any information for the OS, but I'm assuming with the type of processor this will be Linux based?
Comment There is no good marker for the "age" of a cell. (Score 2) 22
There is no good marker for the "age" of a cell.
Google result:
Key Methods Used to Estimate Cellular and Biological Age
https://www.google.com/search?...
Google result:
Key Methods Used to Estimate Cellular and Biological Age
https://www.google.com/search?...
Submission + - Will AI expose the rickety infrastructure of the internet? (techcrunch.com)
sziring writes: A startling announcement went out earlier this week: Due to recently discovered vulnerabilities in the open source programming language PHP, website owners had to immediately patch their sites â" or if they couldnâ(TM)t update right away, they should take the sites down to be safe.
On this weekâ(TM)s episode of TechCrunchâ(TM)s Equity podcast, Kirsten Korosec, Sean Oâ(TM)Kane, and I discussed the significance of the PHP-ocalypse and whether weâ(TM)ll see more incidents like this in the future.
Sean called this âoea real reckoning momentâ that highlights how âoewhen you get down to the bone level of the internet,â everything seems to be âoeheld together by glue and dreams.â And with widespread access to large language models and AI agents, itâ(TM)s only going to become easier to find these vulnerabilities. (That said, these specific vulnerabilities were found by human researchers, not AI models.)
Kirsten, meanwhile, wondered if weâ(TM)re about to see the âoenext level of prepper doom [â¦] because you could see how banks could get exploited, and [with] data and privacy concerns, it just feels a lot bigger than we can fix right now.â
Keep reading for a preview of our conversation, edited for length and clarity.
Sean Oâ(TM)Kane: The internet is breaking in lots of ways this week, it seems.
I think the best way to think about this, if people are coming into this kind of cold: How many times over the last 10 years have we had these moments where something breaks or something nearly breaks, where one person maintaining one tiny repro repository as a hobby or whatever happens to catch that something nefarious is going on and and saves us from the infrastructure of the internet completely crumbling?
Now multiply that by a billion, when people have access to not only extremely advanced software in the form of these LLMs that everybody uses, but also the ability to task them to go out and do it themselves, with creating AI agents that are single-minded at accomplishing those things.
Weâ(TM)re seeing a balance of two things happening this week. One is a bunch of the labs and companies like Google and OpenAI actually had people go out and find a bunch of vulnerabilities, including the one with PHP. And then we also have a bunch of people seeming to rush to take advantage of those vulnerabilities to try and hack into websites. So we have governments taking down websites, we have really popular websites that are going down briefly to be able to fix this vulnerability.
This is a real reckoning moment, where weâ(TM)re going to find out the downside risk of building so much of the internet on open source technology like PHP. When you really get down to the bone level of the internet, it is held together with glue and dreams.
On this weekâ(TM)s episode of TechCrunchâ(TM)s Equity podcast, Kirsten Korosec, Sean Oâ(TM)Kane, and I discussed the significance of the PHP-ocalypse and whether weâ(TM)ll see more incidents like this in the future.
Sean called this âoea real reckoning momentâ that highlights how âoewhen you get down to the bone level of the internet,â everything seems to be âoeheld together by glue and dreams.â And with widespread access to large language models and AI agents, itâ(TM)s only going to become easier to find these vulnerabilities. (That said, these specific vulnerabilities were found by human researchers, not AI models.)
Kirsten, meanwhile, wondered if weâ(TM)re about to see the âoenext level of prepper doom [â¦] because you could see how banks could get exploited, and [with] data and privacy concerns, it just feels a lot bigger than we can fix right now.â
Keep reading for a preview of our conversation, edited for length and clarity.
Sean Oâ(TM)Kane: The internet is breaking in lots of ways this week, it seems.
I think the best way to think about this, if people are coming into this kind of cold: How many times over the last 10 years have we had these moments where something breaks or something nearly breaks, where one person maintaining one tiny repro repository as a hobby or whatever happens to catch that something nefarious is going on and and saves us from the infrastructure of the internet completely crumbling?
Now multiply that by a billion, when people have access to not only extremely advanced software in the form of these LLMs that everybody uses, but also the ability to task them to go out and do it themselves, with creating AI agents that are single-minded at accomplishing those things.
Weâ(TM)re seeing a balance of two things happening this week. One is a bunch of the labs and companies like Google and OpenAI actually had people go out and find a bunch of vulnerabilities, including the one with PHP. And then we also have a bunch of people seeming to rush to take advantage of those vulnerabilities to try and hack into websites. So we have governments taking down websites, we have really popular websites that are going down briefly to be able to fix this vulnerability.
This is a real reckoning moment, where weâ(TM)re going to find out the downside risk of building so much of the internet on open source technology like PHP. When you really get down to the bone level of the internet, it is held together with glue and dreams.
Comment Re: That's awful (Score 1) 55
Exactly, but math is hard.
Also this is a bargain compared to online game prices in the early 90â(TM)s (Neverwinter Online was $6 an hour if I remember (not that I ever played it because of that)
Submission + - The Pentagon is quietly building an elite new tech sabotage agency (yahoo.com) 1
schwit1 writes: The Pentagon has spent months quietly building an elite new tech agency to help covertly disrupt and sabotage foreign technology programs considered threats to American military superiority.
Neither Defense Secretary Pete Hegseth nor any other senior Pentagon official has publicly mentioned the agency since it was established this April — a conspicuous omission for a department that has reveled in announcing other major changes aimed at modernizing the military or adopting hard-nosed new policies against foreign adversaries.
Information on the Technology Support Office, or TSO as it is called internally, is nearly impossible to find on Pentagon websites, and the agency is mentioned by name only in several previously unreported Defense Department historical records and memoranda.
Special Operations Command and U.S. Cyber Command both objected to creating the new agency, fearing it would cut into their budgets, according to the two former intelligence officials and one former senior U.S. national security official.
But by creating an agency dedicated to expanding that work, the Defense Department is signaling its intent to ramp up a range of aggressive covert activities abroad — potentially including cyberattacks, supply chain disruptions and disinformation operations.
Many of the people who spoke argued that the aggressive new initiative is needed to help the Pentagon counter foreign adversaries they say are harnessing artificial intelligence and advanced commercial technologies, such as drones, in creative ways that could erode America's military advantage.
Neither Defense Secretary Pete Hegseth nor any other senior Pentagon official has publicly mentioned the agency since it was established this April — a conspicuous omission for a department that has reveled in announcing other major changes aimed at modernizing the military or adopting hard-nosed new policies against foreign adversaries.
Information on the Technology Support Office, or TSO as it is called internally, is nearly impossible to find on Pentagon websites, and the agency is mentioned by name only in several previously unreported Defense Department historical records and memoranda.
Special Operations Command and U.S. Cyber Command both objected to creating the new agency, fearing it would cut into their budgets, according to the two former intelligence officials and one former senior U.S. national security official.
But by creating an agency dedicated to expanding that work, the Defense Department is signaling its intent to ramp up a range of aggressive covert activities abroad — potentially including cyberattacks, supply chain disruptions and disinformation operations.
Many of the people who spoke argued that the aggressive new initiative is needed to help the Pentagon counter foreign adversaries they say are harnessing artificial intelligence and advanced commercial technologies, such as drones, in creative ways that could erode America's military advantage.
Submission + - Microsoft says October updates didn't actually fix VPN issues (bleepingcomputer.com)
joshuark writes: Microsoft says it mistakenly flagged a bug causing Always On VPN connection issues as fixed in the October 2026 Windows 11 cumulative updates.
Always On VPN replaced the legacy DirectAccess technology and supports domain-joined, non-domain-joined, and Microsoft Entra ID–joined devices running Windows 10, Windows 11, and Windows Server.
It runs in the background and establishes secure tunnels back to the user's corporate network whenever their device connects to the internet.
Microsoft first acknowledged the issue in a service alert sent to IT administrators in late September, saying it was triggered on systems running Windows 11 24H2 and later after installing the September 2026 security updates when the initial Always On VPN connection failed (e.g., when using automatic protocol selection with IKEv2 and SSTP).
"When automatic protocol selection or protocol fallback was configured, affected VPN connections could remain stuck in a Connecting state or fail to connect after an initial connection attempt failed," it said. "In some cases, subsequent connection attempts could display the error, 'The specified port is already in use.'"
After releasing the October 2026 Patch Tuesday Windows 11 cumulative updates, Microsoft marked the bug as resolved, but in a Tuesday update it said the issues weren't actually addressed and that a fix would ship later.
"This disclosure was mistakenly updated to Resolved status on October 13, 2026. We have returned its status to Mitigated," it said in a service alert sent to IT admins. "A resolution for this issue is planned to be included in an update to be released in the coming weeks. We apologize for any inconvenience or confusion."
While Microsoft continues working on a permanent solution, it shared a temporary fix that requires affected customers to choose one of two VPN tunneling protocols to work around the issue.
Always On VPN replaced the legacy DirectAccess technology and supports domain-joined, non-domain-joined, and Microsoft Entra ID–joined devices running Windows 10, Windows 11, and Windows Server.
It runs in the background and establishes secure tunnels back to the user's corporate network whenever their device connects to the internet.
Microsoft first acknowledged the issue in a service alert sent to IT administrators in late September, saying it was triggered on systems running Windows 11 24H2 and later after installing the September 2026 security updates when the initial Always On VPN connection failed (e.g., when using automatic protocol selection with IKEv2 and SSTP).
"When automatic protocol selection or protocol fallback was configured, affected VPN connections could remain stuck in a Connecting state or fail to connect after an initial connection attempt failed," it said. "In some cases, subsequent connection attempts could display the error, 'The specified port is already in use.'"
After releasing the October 2026 Patch Tuesday Windows 11 cumulative updates, Microsoft marked the bug as resolved, but in a Tuesday update it said the issues weren't actually addressed and that a fix would ship later.
"This disclosure was mistakenly updated to Resolved status on October 13, 2026. We have returned its status to Mitigated," it said in a service alert sent to IT admins. "A resolution for this issue is planned to be included in an update to be released in the coming weeks. We apologize for any inconvenience or confusion."
While Microsoft continues working on a permanent solution, it shared a temporary fix that requires affected customers to choose one of two VPN tunneling protocols to work around the issue.
Submission + - Old Blood Cells Have Been Transformed Into Brain Stem Cells That Get Younger (sciencealert.com)
alternative_right writes: Now, scientists have transformed old blood cells into young brain stem cells, which continued to grow younger as they grew older.
The researchers, from the University Hospital of Bonn and the University of Bonn, in Germany, described their methods in the journal Aging Cell.
Cellular transformations can be done in two main ways. The first, more circuitous route turns a specific cell back into a pluripotent stem cell, or an embryonic "blank slate," and then into a different cell type.
The researchers, from the University Hospital of Bonn and the University of Bonn, in Germany, described their methods in the journal Aging Cell.
Cellular transformations can be done in two main ways. The first, more circuitous route turns a specific cell back into a pluripotent stem cell, or an embryonic "blank slate," and then into a different cell type.
Submission + - LLM-inspired study sheds light on how brain cells encode the meaning of words (medicalxpress.com)
alternative_right writes: To investigate how the brain encodes the meaning of words, the researchers first recorded the activity of individual neurons in the hippocampus of 10 people who were listening to stories. Their recordings were collected using tiny wire electrodes that were implanted in the participants' brains as part of clinical monitoring procedures for epilepsy.
The team then used mathematical models to analyze the language used in the stories and the brain recordings. This allowed them to examine whether information about the meaning of words could predict the recorded neuronal activity.
"We recorded responses of hippocampal neurons while individuals listened to narrative speech," wrote Melissa Franch and her colleagues in their paper. "Using an encoding model approach, we find robust encoding of semantics, even after controlling for phonemics and grammar. Individual words had complex selectivities that included multiple words in multiple semantic categories."
The team then used mathematical models to analyze the language used in the stories and the brain recordings. This allowed them to examine whether information about the meaning of words could predict the recorded neuronal activity.
"We recorded responses of hippocampal neurons while individuals listened to narrative speech," wrote Melissa Franch and her colleagues in their paper. "Using an encoding model approach, we find robust encoding of semantics, even after controlling for phonemics and grammar. Individual words had complex selectivities that included multiple words in multiple semantic categories."
Submission + - Amid K-12 AI Pushback, OpenAI Named Lead Partner of 'Hour of AI' for Kids
theodp writes: On the heels of announced AI moratoriums by the nation's two largest K-12 school districts (NYC, LA), tech-backed nonprofit CodeAI (aka Code.org) this week named OpenAI 'Lead Partner' for the 2026 Hour of AI, which has replaced the Hour of Code (RIP, 2013-2024) as the premier event for the nation's K-12 schoolchildren during December's CS Education Week. OpenAI investor and partner Microsoft was named as one of two 'Supporters' for the event/infomercial (the other being U.S. defense contractor Northrop Grumman).
In August, as it launched ChatGPT for Teens, OpenAI announced a new signature partnership with Code.org to 'prepare the first AI generation', explaining that 'through the Hour of AI, OpenAI and CodeAI will introduce millions of students to the basics of using AI thoughtfully and responsibly.' OpenAI and Microsoft last year teamed up with the American Federation of Teachers to 'bring AI into the classroom', but that honeymoon is over. For more on the inside story of how Big Tech is applying the same playbook it used to scale coding lessons nationwide to now mainstream their AI tools in schools, check out Coding Kids: Big Tech's Battle to Remake Public Schools.
So, much like the Hour of Code that preceded it, will the Hour of AI serve as tech's 'Trojan Horse' (ChatGPT-generated parody cover) in its 'Odyssey' to push its agenda and curriculum into schools?
In August, as it launched ChatGPT for Teens, OpenAI announced a new signature partnership with Code.org to 'prepare the first AI generation', explaining that 'through the Hour of AI, OpenAI and CodeAI will introduce millions of students to the basics of using AI thoughtfully and responsibly.' OpenAI and Microsoft last year teamed up with the American Federation of Teachers to 'bring AI into the classroom', but that honeymoon is over. For more on the inside story of how Big Tech is applying the same playbook it used to scale coding lessons nationwide to now mainstream their AI tools in schools, check out Coding Kids: Big Tech's Battle to Remake Public Schools.
So, much like the Hour of Code that preceded it, will the Hour of AI serve as tech's 'Trojan Horse' (ChatGPT-generated parody cover) in its 'Odyssey' to push its agenda and curriculum into schools?
Comment Amazing: Rapid advances in technology (Score 0) 81
There are many ways AI is guiding rapid advances in technology.
The Rapid Trajectory Of Artificial Intelligence
AI revolutionizing industries worldwide: A comprehensive overview of its diverse applications
The Rapid Trajectory Of Artificial Intelligence
AI revolutionizing industries worldwide: A comprehensive overview of its diverse applications
