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Submission + - Scientists Grow Whole Model of Human Embryo, Without Sperm or Egg (bbc.com)

An anonymous reader writes: Scientists have grown an entity that closely resembles an early human embryo, without using sperm, eggs or a womb. The Weizmann Institute team say their "embryo model", made using stem cells, looks like a textbook example of a real 14-day-old embryo. It even released hormones that turned a pregnancy test positive in the lab. The ambition for embryo models is to provide an ethical way of understanding the earliest moments of our lives. This research, published in the journal Nature, is described by the Israeli team as the first "complete" embryo model for mimicking all the key structures that emerge in the early embryo.

Instead of a sperm and egg, the starting material was naive stem cells which were reprogrammed to gain the potential to become any type of tissue in the body. Chemicals were then used to coax these stem cells into becoming four types of cell found in the earliest stages of the human embryo: epiblast cells, which become the embryo proper (or foetus); trophoblast cells, which become the placenta; hypoblast cells, which become the supportive yolk sac; and extraembryonic mesoderm cells. A total of 120 of these cells were mixed in a precise ratio — and then, the scientists step back and watch.

About 1% of the mixture began the journey of spontaneously assembling themselves into a structure that resembles, but is not identical to, a human embryo. The embryo models were allowed to grow and develop until they were comparable to an embryo 14 days after fertilisation. In many countries, this is the legal cut-off for normal embryo research. The hope is embryo models can help scientists explain how different types of cell emerge, witness the earliest steps in building the body's organs or understand inherited or genetic diseases. Already, this study shows other parts of the embryo will not form unless the early placenta cells can surround it. There is even talk of improving in vitro fertilization (IVF) success rates by helping to understand why some embryos fail or using the models to test whether medicines are safe during pregnancy.

Submission + - University of Michigan Halts Internet During First Week of Classes (insidehighered.com)

regoli writes: The University of Michigan cut off internet access and online services across all three of its campuses early this week to ward off a potential cyberattack, leaving students and faculty in digital limbo during the first week of classes. According to the story from Inside Higher Ed, "The FBI’s Detroit field office would not confirm the existence of an investigation into the attack, but the FBI is aware of the outage and prepared to provide assistance if U-M requests it, said Mara Schneider, public affairs officer at the Detroit FBI office."

Submission + - The $53,000 Connection: The High Cost of High-Speed Internet for Everyone (wsj.com)

An anonymous reader writes:

Nebraska’s Winnebago Tribe has long been stuck with sluggish internet service. The federal government plans to fix that by crisscrossing the reservation with fiber-optic cable—at an average cost of $53,000 for each household and workplace connected.

That amount exceeds the assessed value of some of the homes getting hookups, property records show. While most connections will cost far less, the expense to reach some remote communities has triggered concerns over the ultimate price tag for ensuring every rural home, business, school and workplace in America has the same internet that city dwellers enjoy.

“The problem is, money is not infinite,” said Blair Levin, a senior communications policy official in the Clinton and Obama administrations who is now an equity research analyst. “If you’re spending $50,000 to connect a very remote location, you have to ask yourself, would we be better off spending that same amount of money to connect [more] families?”

The U.S. has committed more than $60 billion for what the Biden administration calls the “Internet for All” program, the latest in a series of sometimes troubled efforts to bring high-speed internet to rural areas.

Plus: "In Montana, laying fiber-optic cable to some remote locations could cost more than $300,000 per connection, said Misty Ann Giles, director of Montana’s Department of Administration. Building to those places would empty the state’s coffers, she said: 'That’s when we might not reach everyone.'"

Ya think?

Private Enterprise: Rural users in most places in the US can get Starlink up and running for $599 in hardware, do-it-yourself installation in most cases, and $120 a month for high-speed service.

Submission + - In Its First Monopoly Trial of Modern Internet Era, U.S. Sets Sights on Google (nytimes.com)

schwit1 writes: The Justice Department has spent three years over two presidential administrations building the case that Google illegally abused its power over online search to throttle competition. To defend itself, Google has enlisted hundreds of employees and three powerful law firms and spent millions of dollars on legal fees and lobbyists.

On Tuesday, a judge in U.S. District Court for the District of Columbia will begin considering their arguments at a trial that cuts to the heart of a long-simmering question: Did today’s tech giants become dominant by breaking the law?

Apple execs lose bid to block testimony at Google antitrust trial

Submission + - Experts Fear Crooks are Cracking Keys Stolen in LastPass Breach (krebsonsecurity.com)

AmiMoJo writes: In November 2022, the password manager service LastPass disclosed a breach in which hackers stole password vaults containing both encrypted and plaintext data for more than 25 million users. Since then, a steady trickle of six-figure cryptocurrency heists targeting security-conscious people throughout the tech industry has led some security experts to conclude that crooks likely have succeeded at cracking open some of the stolen LastPass vaults.

Taylor Monahan is founder and CEO of MetaMask, a popular software cryptocurrency wallet used to interact with the Ethereum blockchain. Since late December 2022, Monahan and other researchers have identified a highly reliable set of clues that they say connect recent thefts targeting more than 150 people, Collectively, these individuals have been robbed of more than $35 million worth of crypto.

Submission + - As Hurricane Idalia caused flooding, some EVs exposed to saltwater caught fire (cbsnews.com)

schwit1 writes: Floridians battered by Hurricane Idalia this week may not have expected another threat — that floodwaters could cause their cars to suddenly burst into flames.

Yet that's exactly what happened when two electric vehicles caught fire after being submerged in saltwater churned up by the storm. Firefighters in Palm Harbor, Florida, cited the incidents, both of which involved Teslas, in warning owners that their rechargeable car batteries could combust if exposed to saltwater.

"If you own a hybrid or electric vehicle that has come into contact with saltwater due to recent flooding within the last 24 hours, it is crucial to relocate the vehicle from your garage without delay," the department said in a Facebook post. "Saltwater exposure can trigger combustion in lithium-ion batteries. If possible, transfer your vehicle to higher ground."

The warning also applies to electric golf carts, scooters and bicycles, with lithium-ion batteries potentially sparking a fire when they get wet. More specifically, salt residue remains after the water dries out and can create "bridges" between the battery's cells, potentially creating electrical connections that can spark a fire.

Submission + - Leaked Government Document Shows Spain Wants to Ban End-to-End Encryption (wired.com)

An anonymous reader writes: Spain has advocated banning encryption for hundreds of millions of people within the European Union, according to a leaked document obtained by WIRED that reveals strong support among EU member states for proposals to scan private messages for illegal content. The document, a European Council survey of member countries’ views on encryption regulation, offered officials’ behind-the-scenes opinions on how to craft a highly controversial law to stop the spread of child sexual abuse material (CSAM) in Europe. The proposed law would require tech companies to scan their platforms, including users’ private messages, to find illegal material. However, the proposal from Ylva Johansson, the EU commissioner in charge of home affairs, has drawn ire from cryptographers, technologists, and privacy advocates for its potential impact on end-to-end encryption.

For years, EU states have debated whether end-to-end encrypted communication platforms, such as WhatsApp and Signal, should be protected as a way for Europeans to exercise a fundamental right to privacy—or weakened to keep criminals from being able to communicate outside the reach of law enforcement. Experts who reviewed the document at WIRED’s request say it provides important insight into which EU countries plan to support a proposal that threatens to reshape encryption and the future of online privacy. Of the 20 EU countries represented in the document leaked to WIRED, the majority said they are in favor of some form of scanning of encrypted messages, with Spain’s position emerging as the most extreme. “Ideally, in our view, it would be desirable to legislatively prevent EU-based service providers from implementing end-to-end encryption,” Spanish representatives said in the document. The source of the document declined to comment and requested anonymity because they were not authorized to share it.

In its response, Spain said it is “imperative that we have access to the data” and suggests that it should be possible for encrypted communications to be decrypted. Spain’s interior minister, Fernando Grande-Marlaska, has been outspoken about what he considers the threat posted by encryption. When reached for comment about the leaked document, Daniel Campos de Diego, a spokesperson for Spain’s Ministry of Interior, says the country’s position on this matter is widely known and has been publicly disseminated on several occasions. Edging close to Spain, Poland advocated in the leaked document for mechanisms through which encryption could be lifted by court order and for parents to have the power to decrypt children’s communications.

Submission + - Elon Musk On the Problem With Corporate America: 'Too Many MBAs' (cnbc.com)

An anonymous reader writes: Tesla and SpaceX founder Elon Musk says the biggest problem with corporate America today is that too many business school graduates are running the show. “I think that there might be too many MBAs running companies,” Musk said Tuesday at the WSJ CEO Summit. This “MBA-ization of America,” isn’t great, Musk said, especially when it comes to product innovation. Big corporate CEOs often get caught up in the numbers and lose sight of their mission, which is to create “awesome” products or services, according to Musk.

“There should be more focus on the product or service itself, less time on board meetings, less time on financials.” “A company has no value in itself. It only has value to the degree that is [an] effective allocator of resources to create business services that are of a greater value than the costs of the inputs,” Musk said. This thing they call “profit,” Musk added, “should just mean over time that the value of the output is worth more than the inputs.” Musk said the biggest mistake he has made as a leader of both Tesla and SpaceX was spending too much time in meetings looking at PowerPoints and spreadsheets, instead of being out on the factory floor. “When I go spend time on the factory floor or really using the cars or thinking about the rockets...that’s where things have gone better,” Musk said at the WSJ summit.

He finds that if he is engrossed in the details of the issues, it boosts morale and his team is “more energized.” Musk urged CEOs to “get out there on the goddamn front line and show them that you care, and that you’re not just in some plush office somewhere.”

Submission + - NextMind's brain-computer interface is ready for developers (engadget.com)

clubalien writes: NextMind is the latest in a long line of companies trying to harness the brain as a means of controlling our digital world. At first, its take on things may seem familiar: Don a headset which places a sensor on the back of your head, and it’ll detect your brainwaves which can then be translated into digital actions. One area where NextMind differs is that the sensor seems more practical than many we’ve seen and won’t leave you looking like a shower cap-wearing lab rat. In fact, the wearable can just as easily clip onto the rear of a snapback.

Submission + - SpaceX Starship high altitude test flight ends in a fiery explosion (engadget.com)

Thelasko writes: After a successful launch, the Starship rose and successfully maneuvered its way to the landing area. However, it appeared that the spacecraft didn’t slow down enough for a proper landing, and it exploded in thrilling fashion.

Elon Musk Posted on Twitter:
"Fuel header tank pressure was low during landing burn, causing touchdown velocity to be high & RUD, but we got all the data we needed! Congrats SpaceX team hell yeah!!"

Submission + - Tesla Full Self-Driving System's Beta Developer Settings Leaked (arstechnica.com)

An anonymous reader writes: It's a long time coming for Tesla's Full Self-Driving feature, and it hasn't been a cheap journey. The price for the self-driving feature has increased multiple times and is currently available for supported Teslas for $10,000.While Tesla's Full Self-Driving (FSD) beta continues to expand to more Tesla owners ahead of a planned end-of-year launch, the actual settings for the system have been uncovered and published on Twitter by a well-known Tesla hacker named Green. Not only are there dozens of settings and available adjustments, but there's also a way to show a detailed vehicle view of the world while a Tesla is driving down the road.

In a Twitter thread, Green shares the status of internal states within the system while taking us on a tour of dozens of settings ranging from controls for FSD and Enhanced Summon to information about the Camera and Ultrasonics. The system also shows sliders for GPS, speed threshold, and other items that no one outside of Tesla should ever mess with. There’s also an Augmented Vision area where developers can toggle what's seen on a Tesla display while driving. It includes toggles for Pretty, Developer, and Camera Image. Once Developer is enabled, it shows options for a whole host of data that can be shown on the infotainment system. This all may be information overload for the average Tesla owner, but it's a fun way to get more details on how a Tesla sees the world.

Submission + - 2020 AP CS Scores: Still Big Gaps in Performance, Participation

theodp writes: As the 8th annual Hour of Code kicked off this week, the College Board released 2020 AP national and state score breakouts for AP CS program participants. As in past years, this year's results still showed striking gaps in performance and participation across gender and ethnicity segments.

Passing rates across major ethnic group segments ranged from 39.8%-78.6% for the Java-based AP CS A course, and 52%-83% for the newer "language agnostic" AP Computer Science Principles (CSP) course. Across gender segments, females accounted for 25% of AP CS A scores (16.2K of 64.9K total students) and 33.9% of AP CSP scores (38.6K of 113.9K students). Asian students accounted for 47% of all passing female AP CS A students.

Due to pandemic-related school closures, the overall number of students completing AP STEM-related courses in 2020 declined for all subjects except CS. AP CS A, which had an abbreviated taken-at-home final exam, saw a modest 1.5% YOY increase in completions, while AP CSP saw a whopping 21.5% YOY increase in completions, no doubt helped by the cancellation of its end-of-course exam, which was to have counted for 60% of scores (students were instead assessed only by their portfolio submissions).

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