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Comment Living where? (Score 1, Interesting) 132

Where exactly does supporting 3 people on $133k/year count as 'upper middle class'? You could be doing a lot worse, and many are; but that's not just tons of money in a HCOL area; and that's also lower than twice the median salary for full time employees with bachelor's degrees; so you are calling either a single income household doing a bit better than median or a dual income one doing worse 'upper middle class'; which seems pretty ambitious.

Comment Re:This isn't about the i486 (Score 1) 115

Yeah, Via made a clone that was similar not-quite-i586 fairly recently too.

I have an old embedded box with one that has SATA 6Gbps ports on it that I thought I would use zeroing out old hard drives.

I tried Puppy, DSL, SystemRescueCD, and a bunch of others and none would finish boot. FreeDOS is fine.

It's either eWaste or I need to dig out an Infomagic CD from the attic to get Redhat 9 pr whatever. Probably need to look up when the jump from 3 to 6 happened in SATA land.

But Linus is correct that actual distros don't supoort it. There's one project for composing embedded images that I might try before it hits a shredder. Or NetBSD maybe.

Comment Re:Honey, wake up, new hellscape just dropped (Score 1) 77

Realistically, the status quo has arguably outrun the dystopia there. Your phone already does far more than anything you could get into the power envelope of a bracelet or embedded chip implant, and if for some reason you've raised enough eyebrows that you'd be hauled in for an RFID read DNA is a pretty indelible identifier.

It's not 100% ironclad; but penetration is broad enough that you've basically got the majority carrying highly fingerprintable RF beacons and the minority standing out for their relative radio silence and attempts to deal in cash. Expensive and uncomfortable ankle trackers are good business and feel nice and punitive, just to remind the wrong sort of people we aren't happy with them; but you don't really need to impose a surveillance society when it will build itself for you.

Comment Re:Not a 486 thing, but... (Score 1) 115

My (admittedly anecdotal from the totally unscientific sample of random stuff I've had reason to work on) impression is that some 'shared' BMC ports had oddities related to network controller sideband interface speeds, since NC-SI is what the BMC is depending on if the NIC is on someone else's PCIe root. It's not like the BMC actually needs a faster link for much(normal management traffic probably doesn't fill 10mb and mounting virtual media may be literally once-in-a-lifetime) so the actual speed of the NC-SI interface was not a burning priority; but it left things up to the NIC whether it would support remaining at gigabit speeds and just quietly slipping the trickle of shared traffic in(presumably slightly more complex; but seems to be what the newer ones do) or if it would knock the link rate down visibly to simplify the case.

You see little echoes of similar behavior elsewhere. The intel desktop and laptop NICs that support 'vPRO' will be GB or 2.5GB when the system is on; but quietly drop back to 10 or 10/100 when it is off and it's just the management engine listening. Some enterprise vendor USB docks do similar things; looks like a normal USB NIC when the OS is up; but drops to a lower speed and operates quietly over, I think, some sort of oddball vendor-defined messages if one of their systems is plugged in but off.

Comment Why all at once? (Score 1) 48

I assume that, as an exercise, getting 5 simultaneous introductions working makes for a better paper; but is there a reason why you would want that in practice? Especially if there is any wobble in the ratios either randomly, across generations, or in the presence of certain environmental conditions that tweak the plant's metabolism one way or another that sounds like it would be a real pain in the ass to have to re-balance (and, if different patients are deemed to need different combinations even a perfectly stable plant is going to need re-balancing of the outputs) vs. very specifically going for a specific target output per-plant(or e. coli or yeast or whatever is easiest to bioreactor) and then just mixing to taste after purification. Is there some advantage I'm not seeing?

I realize that there are cases where some plant-sourced pharmacological effect looks like it is actually driven not by the identified 'active ingredient'; but by dozens or hundreds of assorted things, and in that case you just have to live with the complexity if you get better results with that than with purified isolates; but if you are deliberately engineering for very specific outputs why a mix of 5?

Comment Re:Unfortunately this doesnt look like an April fo (Score 2) 48

Aside from it just being a scientific research project, in practice even if they were produced in combination it's almost certain that they would be refined and purified for medicinal use.

But it would be much easier to not have to separate them and do one molecule per plant/field.

That aside your monoamine oxidase would prevent all but the psylocin from being orally active. Maaybe if the tobacco were very carefully dried and not fermented you could smoke it.

Now if they were to engineer in some harmaline/telepathine and put it into a tomato you could make some very special marinara sauce. The acids would act like a 'lemon-tec' and heating could perhaps be doing some decarboxalating. I have no idea if people experiment with mushrooms and ayahuasca simultaneously.

I can't wait for the Epstein Class to start raiding pasta shops to protect their black markets. :/

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