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Comment Re:Isaacman is not immune to the disease (Score 1) 19

This, though for the most part, you don't need the whole rover — only its brain (and perhaps its communications electronics). The situations where you need the whole rover involve figuring out how to get it unstuck. And the more experience they have at running the things around on Mars, the less likely that becomes.

Comment Re:Loophole (Score 1) 108

I think before when battery tech was much more expensive this would have been a possibility. With battery prices what they are now and falling, I expect the more likely scenario is that batteries get bought to store the excess. And given AI insatiable appetite for juice, I expect every watt that can get built will get consumed. I think I saw consumption today on the ERCOT grid is projected to be around 85GW peak. And it is not even hot yet. I remember just a few years ago 85GW would have been record consumption territory. Now it is meh. The good news is I think a little over 50 of that will be wind/solar today. Not positive, but I think fossil production may actually be down a bit this year relative to 5 years ago. Renewables in TX and batteries shoving up to 8GW into/out of the grid regularly. Who'd a thunk.

Maybe, but if there's a useful place to put excess production it can definitely be more cost-effective to do that... and carbon recapture is definitely something worth doing, and could probably be done intermittently. We just need a way to pay people to do it, pay them enough that it's worthwhile. Note that it doesn't have to be worthwhile now, we can new tech that makes it more efficient, but the pay on offer has to be high enough that people think there might be some path to profitability.

Comment Re:Loophole (Score 1) 108

Nobody's pursuing such initiatives. Doing so would be even more expensive than net zero emissions policies.

We definitely need to start pursuing it, at least researching it. We'll never solve the climate change problem with emissions reduction alone, recapture and sequestration will be essential.

There are some strategies which are pretty cheap, such as planting forests. But the numbers don't add up on that; we'll need more. I think carbon recapture systems may pair fairly naturally with renewable energy generation, though. Renewable variability means that in many cases it makes sense to overprovision. For example, in order to get sufficient power generation from a solar plant on cloudy days, you may install 2X-3X as many panels as you'd need for a sunny day... but that means that on sunny days you have lots of excess production that might be hard to use (I experience that with my rooftop solar; last month I generated just over 1 MWh that I couldn't use and the grid wouldn't pay me for). Using that excess to power carbon recapture would be a good idea.

For that to work, though, we need to arrange some financial reason for people to build and operate carbon recapture systems. That's a big missing piece which only government can solve. The obvious solution (to the entire climate change problem, actually!) is refundable carbon taxes plus carbon tariffs.

Comment Re:Global Warming is Hitting Florida Hard (Score 1) 108

However, Florida is a small enough part of the global problem, that what they do locally will have essentially no effect. They couldn't fix the problem with local actions, and they also probably can't make it measurably worse.

Note that the US is not such a small part. That's a large enough fraction of the problem to make a measurable difference. Scale is significant.

Comment Re:Shocked (Score 1) 17

I'm amazed that any company relies on anything from Google...with them shutting things down and deciding not to provide services to huge chunks of the world. I guess it's time for me to review my use of all things Google, again...

If your concern is that a product you use might be discontinued, there are some simple rules that you can apply to decide whether a given Google product is safe from being discontinued:

(1) Is it used by 100M+ people? If it is, it's safe. If the number is 10M+ it's probably good, but there's a risk. If it's less than 10M, it probably won't last. Unless...
(2) Is it a paid service? Paid services rarely get shut down, and if they do Google bends over backwards to make t right.

If it's free and has a small (for Google) userbase? It's all but guaranteed to get shut down. Google is a business. They make a lot of products that are free to use, but only because they can bundle ads with them or otherwise profit from them, but free-to-use products require a large user base to generate much revenue.

Comment Re:alito barrett and thomas dissent (Score 1) 69

20 years ago, which was a few years after conservatives supported the Patriot Act which greatly increased govt surveillance of US citizens? Yeah, no real changes. The folks who want the police state now are the folks who have always wanted the police state (mostly through some idiotic idea that THE OTHER will be persecuted, but never themselves).

The Democrats also voted overwhelmingly in favor of the PATRIOT ACT.

Typical. Modded down for making a simple, incontrovertible statement of fact.

Comment "one step away" yeah right. (Score 3, Informative) 44

It's not anywhere near one step away. Designing the peptides and getting one or more candidates is the easy part. The next steps are the hard ones, the ones that make pharmaceutical chemists and drug researchers cry:

  • Phase I trials to see if it even works as claimed. Expect a 95+% failure rate here. Note that this is where you're going to see the best results for your drug candidate, things never improve from here. The best you can hope for is that they don't get any worse. So if you don't get strong results here you're probably wasting your money.
  • Phase II trials to determine the best dosage and pharmacokinetics. Again expect a 95+% failure rate here, and results showing less effectiveness than shown in Phase I.
  • Phase III trials to determine behavior in a large sample representative of the target population. Expect a failure rate upwards of 99% here, and a major drop-off in effectiveness. This is where toxicity and serious negative side effects show up, and those can kill your trial dead even if your candidate is working.

Getting through this process will take multiple tries and years of work, assuming you succeed at all. There's a reason they say that the clinic (clinical trials) is where drug candidates go to die.

Comment Re:Oh, right! (Score 2) 70

The 2000 settlement with Microsoft was right in time for Caldera to take the $280 million, buy SCO (Santa Cruz Operation) assets, rename itself "The SCO Group", which it then leveraged in the infamous 2003 SCO vs IBM lawsuit claiming Linux infringed the SCO-licensed (but Novell owned since 1993) AT&T copyrights. Caldera's (aka The SCO Group's) lawsuit collasped when it was revealed that SCO did not own the AT&T Unix copyrights, but that AT&T had sold them to Novell and Novell had merely licensed them to SCO.

Yep.

Even without the ownership issue it would almost certainly have failed because TSG (to distinguish them from SCO) discovered to their shock and amazement that Linux had not, in fact, kifed code from Unix. They clearly went into it assuming that a bunch of volunteer hackers couldn't possibly have built a fully-functional kernel, expecting they could easily prove lots of copyright infringement. Failing to find infringement they hoped they could bluster IBM into settling, but IBM was determined to fight it out and had much better lawyers (heh, we used to call them the Nazgul).

Many of us were disappointed when the ownership issue was revealed. We really wanted Linux to get its day in court. As it turned out that didn't matter; no one else was ever dumb enough to try. Today, of course, the biggest tech companies in the world -- which means the biggest companies in the world! -- almost all use Linux extensively. Even Microsoft would probably stand up to defend Linux these days.

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