Nobody ever says, "Gee, this marijuana is entertaining, I think I'll go buy a bag of gross dirt that's been in someone's rectum and inject the liquified contents into my arm!"
But I knew kids in HS (20 years ago) who were reduced to writhing-on-the-floor tears when their Oxy connection went dry. It would take more than two hands to count just the kids from my community and age group, that I knew, who've died from opiates, including a dear friend of mine. Dozens more who were or are in the thick of it. And from everything I can gather, not one of them started that journey with an opiate that was illegally produced.