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Comment This was already decided way back when (Score 1) 50

This was already decided during the original trial. Two things will prevent Xinuos from succeeding:

1. SCO never had a license to the code they claim to own. They had a license to distribute it, but Novell owned the copyrights (such as they were).

2. The code SCO claimed was copied from Project Monterey wasn't in fact copied from there. It was original code IBM wrote and contributed to Monterey (while retaining the copyrights) and then subsequently contributed to Linux (which they had every right to do because the license granted to Monterey wasn't exclusive).

The only reason the lawsuit ended with a settlement was that SCO had lost on every argument and gone bankrupt, so there was no money to pay any judgement against them. I suspect some of the terms of that settlement are going to come back to bite Xinuos, because SCO had managed what everyone had considered impossible: they'd not only angered IBM enough they were out for blood, they'd managed to get IBM's law firm (Cravath, Swaine and Moore, who are a big name) personally angry at them too. I'm fairly sure there's terms in that settlement expressly to make sure that dead horse stays dead and buried. Given that Xinuos isn't bankrupt, and some of the figures behind SCO and the original lawsuit were involved with them last I heard, I expect IBM's attorneys to make great white sharks look cute and cuddly by comparison.

Comment Not a glowing recommendation (Score 1, Interesting) 103

So let me get this straight. If I live in a hot or cold environment, and/or I regularly use the advertised range (or as much of it that the car will give me, realistically) to avoid having to sit and wait for fast charge to 80% for an hour on a road trip, I'm looking at (probably) no more than 80% capacity available after 5 years?

That torpedos the used market solidly. No wonder they're available so much cheaper.

Comment Re:Silver linings (Score 1) 92

we no longer live in First World countries where you can rely on the power to stay on

Speak for your country, not the rest of the First World. I haven't experienced a power outage since I left N. America in 2008. Given the lag in grid investment here in the UK to reshape it with all the changes, that might change. But for now, it's been incredibly stable.

Comment Re:Concorde was LOUD! (Score 1) 131

Maybe I wasn't clear: Concorde was loud, irrespective of whether the throttle was fully on and afterburners lit, or not.

I'm also glad we don't get any 747s anymore, which were quieter than Concorde. 777s are definitely the ones I've noticed to be loudest these days, especially when planes are coming over every three minutes from 04:30-05:00 in the morning. They're offensively loud compared to the 787s and A350s, and even A380s. But this is a different story.

Comment Re:US senators ae shiteaters who swallow (Score 1) 131

I've heard this theory too, including from my own father. Maybe that's how it was portrayed in the British media at the time? I can't really find much evidence for it on the internet though. As far as the written history on the Internet goes, it's mostly about the noise. Maybe hysteria about the topic was whipped up for political reasons, but where's the evidence now?

There certainly were bans put in place for political reasons, such as India and Malaysia banning Concorde because they couldn't get the access they wanted in terms of landing slots:
https://en.wikipedia.org/wiki/...

Comment Concorde was LOUD! (Score 4, Informative) 131

It wasn't just the sonic booms, this plane was just all around loud. It was a civilian plane afterburners! As somebody who lives about 500m directly under one of Heathrow's landing flight paths, I'm happy it's not coming over anymore.

I've always liked this video though. It starts off so quiet, suburban and banal, and then Corcorde roars over and shatters the scene, setting off a car alarm.
https://www.youtube.com/watch?...

Of course, there are lots of videos like this one too, also setting off car alarms:
https://www.youtube.com/watch?...

Comment "one step away" yeah right. (Score 3, Informative) 49

It's not anywhere near one step away. Designing the peptides and getting one or more candidates is the easy part. The next steps are the hard ones, the ones that make pharmaceutical chemists and drug researchers cry:

  • Phase I trials to see if it even works as claimed. Expect a 95+% failure rate here. Note that this is where you're going to see the best results for your drug candidate, things never improve from here. The best you can hope for is that they don't get any worse. So if you don't get strong results here you're probably wasting your money.
  • Phase II trials to determine the best dosage and pharmacokinetics. Again expect a 95+% failure rate here, and results showing less effectiveness than shown in Phase I.
  • Phase III trials to determine behavior in a large sample representative of the target population. Expect a failure rate upwards of 99% here, and a major drop-off in effectiveness. This is where toxicity and serious negative side effects show up, and those can kill your trial dead even if your candidate is working.

Getting through this process will take multiple tries and years of work, assuming you succeed at all. There's a reason they say that the clinic (clinical trials) is where drug candidates go to die.

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