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Submission + - Researchers completely eliminate pancreatic tumors in mice. (www.cnio.es)

fahrbot-bot writes: Mariano Barbacid, head of the Experimental Oncology Group at the National Cancer Research Centre (CNIO), has designed a therapy that successfully eliminates pancreatic tumours in mice completely and durably, with no significant side effects. The study is published in the journal PNAS (Proceedings of the National Academy of Sciences), with Carmen Guerra as co-lead author and Vasiliki Liaki and Sara Barrambana as first authors.

Current drugs for pancreatic cancer lose effectiveness within months because the tumour becomes resistant. The group from Spain’s National Cancer Research Centre (CNIO) has been able to avoid the development of resistance in animal models with a combined triple therapy.

These results “pave the way for the design of combined therapies that may improve survival,” the authors indicate, although this will not happen in the short term. The results are published in PNAS.

Submission + - Was Waymo Robotaxi Speeding Before It 'Made Contact with a Young Pedestrian'? 3

theodp writes: The self-congratulatory, yea-we-hit-the-kid-but-you-would-have-done-lots-worse tone of Waymo's blog post response to its Waymo robotaxi hitting a child near an elementary School in Santa Monica seemed a bit tone deaf, even more so as commenters pointed out and Google Maps images appeared to confirm that the posted speed limit around Grant Elementary School in Santa Monica is 15 mph (Google Maps link, screenshot) when children are present and Waymo self-reported that the robotaxi's speed was "approximately 17 mph" when it spotted the "young pedestrian" and "braked hard" to reduce the car's speed "to under 6 mph before contact was made." Waymo did not mention what the speed limit was in its self-described ‘transparent’ blog disclosure.

Not that going 17 mph in a 15 mph zone is the stuff of street drag racing, but it's at odds with the attaboy Waymo gave itself for softening the blow to the child as well as an earlier Waymo blog post that boasted "the Waymo Driver is always alert, respects speed limits."

From a National Highway Traffic Safety Administration report on the incident: "NHTSA is aware that the incident occurred within two blocks of a Santa Monica, CA elementary school [a Jan. 23rd police call report puts the location as the 2400 block of Pearl St.] during normal school drop off hours; that there were other children, a crossing guard, and several double-parked vehicles in the vicinity; and that the child ran across the street from behind a double parked SUV towards the school and was struck by the Waymo AV. Waymo reported that the child sustained minor injuries. [...] ODI [Office of Defect Investigation] has opened this Preliminary Evaluation to investigate whether the Waymo AV exercised appropriate caution given, among other things, its proximity to the elementary school during drop off hours, and the presence of young pedestrians and other potential vulnerable road users. ODI expects that its investigation will examine the ADS’s intended behavior in school zones and neighboring areas, especially during normal school pick up/drop off times, including but not limited to its adherence to posted speed limits. ODI will also investigate Waymo's post-impact response."

Submission + - Aurora Watch in Effect as Severe Solar Storm Slams Into Earth (sciencealert.com)

alternative_right writes: Thanks to a giant eruption on the Sun and a large opening in its atmosphere, we're currently experiencing G4 conditions – a severe geomagnetic storm strong enough to disrupt power grids as energy from space weather disturbances drives electric currents through Earth's magnetic field and the ground.

Experts say the storm could even reach G5 levels, the extreme category responsible for the spectacular auroral activity seen in May 2024.

Submission + - cURL removes bug bounties (etn.se)

jantangring writes: Open source code library cURL is removing the possibility to earn money by reporting bugs, hoping that this will reduce the volume of AI slop reports. Joshua Rogers – AI wielding bug hunter of fame – thinks it's a great idea.

cURL maintainer Daniel Stenberg famously reported on the flood AI-generated bad bug reports last year –

”Death by a thousand slops.”

Now cURL is removing the bounty payouts as of the end of January.

"We have to try to brake the flood in order not to drown”, says cURL maintainer Daniel Stenberg to Swedish electronics industry news site etn.se.

Despite being an AI wielding bug hunter himself, Joshua Rogers – slasher of a hundred bugs – thinks removing the bounty money is an excellent idea.

”I personally would have pulled the plug long ago,” he says to etn.se.

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