My personal mod troll is SO MAD I EXIST.

Rent free all day, all night. They never stop thinking about me.

Then why are you only demonstrating a child's understanding of the situation? A malignant state in decline having massive manufacturing capability is not a positive thing.

This is a meaningless statement. I too can create a tool to generate a list of peptide candidates with minimal effort. It may even be somewhat useful if it based peptide sequences on homology searches or some other relevant biology instead of random string generation. This has been an active area of research for than 20 years. In order for this to be newsworthy. Claude has to be better than what already exists. How many novel candidates does it generate that actually have useful antibiotic properties? Do I have to screen through a list of 100 candidates to find one that actually works? If so, that’s not much better than a BLAST search and it costs a lot more. What is the strain selectivity of the new antibiotic? Is it broad or narrow spectrum? How easy is it to manufacture? Are there any toxic side effects?

Assuming a new antibiotic is actually what’s needed, instead of using one of the many beta-lactams or combination therapies that already exist, generating the candidate is the first and easiest step of a long and expensive process to developing a novel drug.

It should be fairly easy to carve out provisions for exceptional circumstances (ex: bankruptcy proceedings), and is probably common practice already. But I agree the language has an implied target which is not good for getting legislation passed, generally. It should be possible to propose reasonable accommodation for majority circumstances without sounding like a manifesto.

That will run into problems with federal copyright laws and other IP protections. While it sounds just, it is unlikely to get anywhere. More likely is large companies would have to have an end-of-life plan for their product (which they likely do already) that includes considerations for how to keep the game playable after servers are taken offline. It could be as simple as releasing the protocol to enable third parties to host servers. Or, better, designing the game for offline play from the beginning so that the final patch set is just a simple switch.

Regardless of the outcome, however, this really does seem like a pre-eminent example of “first world problems”.

I'll never buy one again anyway because they destroyed mine with updates. It was always laggy, but it became basically unusable.

You're hallucinating. I didn't link shit. TFS did:

"The forecast was recorded in 2014 as part of a campaign coordinated by the World Meteorological Organization (WMO) that invited about 60 presenters worldwide to imagine a weather report from the year 2050. In one clip [...]"

Just go back to sucking Greta's clit whilst pretending to care about science. You've wasted enough of my time.

When I went to work for post-acquisition Tivoli (IBM) they issued everyone two PCs, for the most part a pair of PPro 180s, one running Windows 2000 and one with OS/2 so that you could use it to run ACME, a screen scraper GUI for RETAIN. You had to keep Windows so that you could run Notes, but if you just used a 3270 emulator and learned to use the application directly (which was often necessary since ACME updates would lag RETAIN) then you didn't need OS/2 any more. So yes I had to have Windows, but then I also had another machine on which I could run whatever I wanted.

The Windows machine came in handy for Diablo anyway.

>"I have never worked anywhere in my entire career where Windows wasn't the standard, dictated OS. Linux at home, Linux on the server, but there has always been a Windows PC on my work desk. Unfortunately."

Well, where I work, Linux is the standard on all machines- servers (10+) and desktops (270+). Has been for decades. And I am not even counting the switches, routers, door control system, HVAC control, electronic signs, sensors, access points, etc, all of which also run Linux. We do have a few MS-Windows VM's for a few edge cases.

We used Unix before Linux, so it was a natural progression that never included MS-Windows. No desktops have ever been MS-Windows. Not that we haven't had challenges. But zero regrets.

Thanks for proving my point. I don't know why you do that so readily, but I do appreciate it. Of course, you won't understand how you've done that, but we can add it to the list.

You appear to have your head in the clouds. Reality is where shit happens. Pretending otherwise is what's tiresome.

I used to think that. Then I looked at the math. The amount of money possessed by the billionares and a trillionare pale in the face of the size (and needs) of the actual economy. Just having no rich people doesnâ(TM)t mean society suddenly has a bunch of wealth. Like you can generate wealth once, for like a year, and then there is nobody to take money from any more, and everyone is back where they were: same expenses, same income as today. But mysteriously, nobody wants to make businesses actually workâ¦. So the income starts to decay, the prices rise, and with nobody to blame, people start going really weird. And everyone feels that they have a veto power over anything that bothers them, so: bye-bye innovation of every kind. Look at how neighbors police their neighborhoods, and then scale that to every business civilization-wide. Nothing new will ever be created. âoeSafety.â âoeEnvironment.â âoeThreatening jobs.â Everything just⦠stops.

The only VM with good Windows accelerated graphics performance is VMware, period. It feels gross to write that, but it's true.

I have one for space cadet pinball...

You failed to read between the lines there.

You think it's not an problem if a hostile superpower with massive manufacturing capacity is going to go through some hard times?

You remind me of Macron being all happy to make Trump sign a treaty at Versailles. How did that go the last time?

The problem is government. OK, nobody takes government IT seriously and for good reason, but they still need to interface with the government constantly. Since every fucking governmental entity in the USA is based on Windows and IBM, we're all forced to be able to interoperate with those. Microsoft has deliberately made their Office suite non-interoperable with false standards that require epic effort to duplicate to a working extent.

Local governments use Windows to interoperate with State govs. State govs use Windows to interoperate with the feds. Microsoft is a defense contractor and part of the panopticon (literally every whistleblower has had something to tell us about how our government uses their control over Microsoft to spy on us, they're a known member of PRISM, etc.) so the feds will "never" stop using Windows, and trying to keep the rest of us using it too.

I put never in quotes because sure it can change... but only way too late.