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Patient Revives After 19 Years By Rewiring Brain 419

dylanduck writes "A study of the recovery of a man who spent 19 years in a minimally conscious state has revealed the likely cause of his regained consciousness - his brain rewired itself around the injured areas into totally novel structures. It suggests the human brain shows far greater potential for recovery and regeneration then ever suspected." From the article: "There were ... significant changes between scans taken just two months after the recovery, and the most recent, at 18 months. Some of the new pathways had receded again, while others seem to have strengthened and taken over as Wallis continued to improve."
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Patient Revives After 19 Years By Rewiring Brain

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  • Re:Terri Schiavo... (Score:5, Informative)

    by ScentCone ( 795499 ) on Tuesday July 04, 2006 @10:18AM (#15655984)
    Terri Schiavo ... was unavailable for comment.

    Thanks for taking one for team and saying what everyone else was thinking. But just in case anyone is really thinking there's an important parallel there or anything, remember that her case was substantially different: most of her brain was literally dead and gone - actually a mush of fluid. Rewiring "around" an injured area (as in the case cited) depends upon having surrounding brain material that's still viable. She was coasting on real low-level left-overs, and there simply wasn't a platform for that sort of recovery.
  • Re:19 years? (Score:3, Informative)

    by aymanh ( 892834 ) on Tuesday July 04, 2006 @10:26AM (#15656020) Journal
    From TFA:
    Within a few weeks he had stabilised in a minimally conscious state, which his doctors thought would last indefinitely. It did indeed persist for 19 years. Then, in 2003, he started to speak.
    It appears that he was conscious of his surroundings, but not interacting with them (didn't move or speak), however he didn't reach brain death [wikipedia.org] because he retained minimal consciousness.

    IANAD by the way.
  • Re:Rewiring speed up (Score:2, Informative)

    by Alexandra Erenhart ( 880036 ) <saiyanprincessNO@SPAMgmail.com> on Tuesday July 04, 2006 @10:42AM (#15656098) Homepage
    I hope you're joking. The article clearly states that the guy wasn't braindead, but remained with minimal cousciousness. He wasn't dead at all.
  • Re:Terri Schiavo... (Score:3, Informative)

    by DaveInAustin ( 549058 ) on Tuesday July 04, 2006 @11:04AM (#15656183) Homepage
    Her brain damage was caused by oxygen deprivation [wikipedia.org], not a physical trauma. While it's very rare for someone to come back from a brain injury like Mr. Wallis' after being in a coma for more than a few years, it has never happened for someone like Ms. Schiavo.
  • by JSchoeck ( 969798 ) on Tuesday July 04, 2006 @11:07AM (#15656197)
    Even though I know you're just joking, here an answer: No, because the high energy of x-rays will damage your body severly. Oh, and of course because x-rays aren't so common unless you actually have a source (or float around in space). So not much to see and if you do those newly gained receptors would be broken pretty soon again. I think. ;)
  • by Wireless Joe ( 604314 ) on Tuesday July 04, 2006 @11:09AM (#15656203) Homepage
    Besides, would you really want to wake up 20 years older, with years of rehabilitation to look forward to?
    My son developed Periventricular leukomalacia (PVL) soon after he was born. PVL is usually characterized by large cysts in the brain that affect particular functions. In my son's case, the PVL was diffuese and spread throughout his brain in small, rice-grain sized cysts and affects his general functionality. We're not "keeping him alive" in a medical sence, but he does seemed destined to spend the rest of his life in a "minimally conscious state".

    He's four years old now, and I would love if my son, at any age, woke up one day and started to learn the things he's missed (talking, crawling and then walking, etc). My wife and I read a lot about brain injury and the possibility of his recovery. The nature of his injury always gives me hope that because the damaged areas are so small, it may be easier for his brain to compensate.

    Unfortunately, because of the state of medical research in the USA (stem cell especially), My family is probably going to have to travel to another country to take advantage of any treatments that may be developed in the next few years.
  • by tpjunkie ( 911544 ) on Tuesday July 04, 2006 @11:12AM (#15656217) Journal
    I hate to feed the troll, but Terri Schiavo's brain was destroyed. She was blind, brain dead, and for all intents and purposes, a shell. There's a huge difference between her case, and this one.
  • Re:Please note... (Score:5, Informative)

    by brunes69 ( 86786 ) <[slashdot] [at] [keirstead.org]> on Tuesday July 04, 2006 @11:47AM (#15656352)
    You are referring to an urban legend that is not true. It results from a mis-quotation around the idea that for any one task you use about 10% of your brain - but for a variety of different tasks you use all of it.

    See http://www.snopes.com/science/stats/10percnt.htm [snopes.com] for more info.
  • More information (Score:3, Informative)

    by lazybratsche ( 947030 ) on Tuesday July 04, 2006 @12:16PM (#15656480)
    I couldn't find the actual published study that the New Scientist article (sort of) referenced (maybe it hasn't been accepted for publication yet?). However, I did find this article [perpich.com] by the auther mentioned, which is a very readable look at a few cases of brain-damaged patients (including an explanation as to why Terry Schaivo isn't in the same category at all). Unfortunately it doesn't go very in depth into the details of how Willis' brain rewired itself, which I was interested in. Still, very informative reading.
  • Re:Terri Schiavo... (Score:4, Informative)

    by MightyMartian ( 840721 ) on Tuesday July 04, 2006 @12:26PM (#15656524) Journal
    It hardly defies our current knowledge of the brain. Rewiring happens in stroke victims, for instance. Mrs. Schiavo's forebrain was missing entirely, replaced by cerebral fluid. Rewiring is one thing, but the only thing that would have made her better would have been regrowing.
  • by Asklepius M.D. ( 877835 ) on Tuesday July 04, 2006 @12:27PM (#15656529)
    Just as a point of clarification...."minimally concious" is different from the "persistent vegetative state" ascribed by physicians to Terri Schiavo. The EEG and CAT scan of the former show a viable, though damaged, brain with persistent activity that remains even while the patient is unresponsive (which is not the same as unconcious). The EEG and CAT scan of the latter show no viable brain activity above the brain stem and no amount of "rewiring" will change matters. Using the analogy of a (simplified) power grid, the first is like knocking out a couple of distribution stations, the second is like knocking out the dam...the water still flows but it serves no useful function.
  • by Anonymous Coward on Tuesday July 04, 2006 @12:27PM (#15656531)
    the young woman who was, like this gentleman, in what many people called a "persistent vegetative state".

    While Schiavo was in a vegetative state and had no hope for recovery, this man was in a minimally conscious state. If this man had been in a persistent vegetative state, he would not be recovering (albeit very slowly and with little hope of his former abilities) today. It is a significant mistake to equate these two states.

    Would there ever be a chance S[c]hiavo could've recovered like this man did?

    No.
  • Re:Terri Schiavo... (Score:4, Informative)

    by Cecil ( 37810 ) on Tuesday July 04, 2006 @12:38PM (#15656572) Homepage
    Except that a hemispherectomy isn't recoverable once your brain is developed. Although the wikipedia entry does not explicitly say so, it does suggest from the pediatric links and occasional use of the world 'child' that hemispherectomies only work on very young children, before their brains have developed to be reliant on both hemispheres.
  • Re:Terri Schiavo... (Score:5, Informative)

    by ceoyoyo ( 59147 ) on Tuesday July 04, 2006 @01:06PM (#15656659)
    A hemispherectomy is not a half brain lobotomy. At a (very) high level your brain consists of four major anatomical regions, the brain stem, cerebellum and the two hemispheres of the cerebrum. The cerebellum is known to handle coordinated motions and looks like it's involved in memory too. The brain stem is the oldest part and takes care of all the vital functions like breathing. The cerebrum is where most of the interesting stuff happens, like personality, intelligence, voluntary movement and processing of sensory information.

    A hemispherectomy removes up to half of the cerebrum. To be technically alive you only need an operating brain stem. The brain stem isn't plastic though -- it won't rewire itself to make you conscious again. Only the cerebrum can do that.

    So the difference between Terri Schiavo and this guy is that Ms. Schiavo had a devastated cerebrum and enough brian stem left to keep her sort of alive. This guy had some localized damage that happened to be in a critical area.
  • Re:Terri Schiavo... (Score:3, Informative)

    by TubeSteak ( 669689 ) on Tuesday July 04, 2006 @01:23PM (#15656729) Journal
    While it's very rare for someone to come back from a brain injury like Mr. Wallis' after being in a coma for more than a few years, it has never happened for someone like Ms. Schiavo.
    The irrational (yet semi-logical) response to that statement would be: Maybe that's because they didn't wait long enough in Mrs. Schiavo's case.

    I know, her brain was part mush, but that really wasn't the point as far as the uber-fundies were concerned. They (and certain moran Senators/Congressmen) claim she was not in a veggie state & therefore might someday make a recovery.

    IMHO, that's why all the mainstream news reports mention that this would never have happened to Mrs. Schiavo. That said, it wouldn't surprise me if this story started popping up without that qualifier.

    This guy [floridabap...itness.com] (notice the newspaper's name) is still fear mongering about the "culture of death" and the "highly misleading" media reports.

    Anyways, Schiavo is the news story that won't go away
    http://news.google.com/news?q=schiavo [google.com]
  • by ClamIAm ( 926466 ) on Tuesday July 04, 2006 @02:55PM (#15657047)
    I don't think you understand the meaning of the word "potential".
  • by hernick ( 63550 ) on Tuesday July 04, 2006 @03:55PM (#15657238)
    Terry woke up three years ago, and the story was rather widely reported back then. In fact, Terri Schiavo has, in her time, often been compared to Terry - in fact, their medical cases share almost no similarities.

    The story itself has woken up in 2006, for reasons unknown. You can find a better article than the one of the front page at http://www.nature.com/news/2006/060703/full/060703 -5.html [nature.com]

    This everything2 article is probably the best I found about Terry, including updates from 2004: http://www.everything2.com/index.pl?node_id=147582 5 [everything2.com]

    Also, some updates on the family's fight with health services, from 2005: http://www.newsmax.com/archives/articles/2005/6/21 /143438.shtml [newsmax.com]
  • by MobileTatsu-NJG ( 946591 ) on Tuesday July 04, 2006 @05:40PM (#15657507)
    "A full recovery never happens, except in movies. People don't just wake up from a coma. The damage affects them for the rest of their lives. After 19 years, the person you knew would be a stranger to you anyway, and there's not much of that person left."

    I've seen this man on television a year or two ago. (This was before the recovery this article is talking about.) His speech was slurred rather badly and he had trouble putting sentences together. I first read about him on Slashdot and thought "Wow, this guy's going to hear about 20 years of world events for the first time. He's going to hear about the internet and cell phones and DVDs and all that other neat stuff." I was actually envious of him in a superficial way. (What can I say? My imagination got the better of me!) When I saw him on TV, all that optimism died. I really didn't feel like any of this could be explained to him in a way that would make much sense to him. Like you said, he wasn't asleep all these years, he was severly brain damaged.

    I wish him a good recovery, but I think you're right.
  • by Alsee ( 515537 ) on Wednesday July 05, 2006 @05:22AM (#15659070) Homepage
    So who am I supposed to believe? The guy who's paying out settlement money to continue her medical care, or the medical staff who probably wanted her organs, or the priest and family who supposedly have Terri's best interests at heart?

    How about you go with the autopsy?

    The brain itself weighed 615 g, only half the weight expected for a female of her age, height, and weight. Microscopic examination revealed extensive damage to nearly all brain regions, including the cerebral cortex, the thalami, the basal ganglia, the hippocampus, the cerebellum, and the midbrain. The neuropathologic changes in her brain were precisely of the type seen in patients who enter a PVS following cardiac arrest. Throughout the cerebral cortex, the large pyramidal neurons that comprise some 70 percent of cortical cells--critical to the functioning of the cortex--were completely lost.

    The cortical neurons, the ones that do the thinking, the ones that make a person a person, where completely GONE.

    Kidney and other various tissue that still lives and works does not a living person make. Kidney and other various tissue that is dead or gone not make a person dead. The only organ that matters, the only tissue that matters, the thinking cortical brain neurons where completely gone. Not just dead brain tissue, but gone brain tissue. Dead and disintegrated. Terri died so long ago that she had long ago returned to dust. The only organ that mattered had died and disintegrated and returned to dust long ago.

    All that remained of brain tissue were autonomic reflexes and a shriveled mush of non-thinking support cells. The blood vessel cells remained, the connective support cells remained, but the thinking neurons were gone. A small shriveled lump of empty goo.

    So who am I supposed to believe?

    Had you looked into the facts and the science of the case, had you paid attention to the calm reasonable rational court review and rulings on the case, it should have been easy to spot that one side of the fight was the "reality based community" and had the facts of reality on their side, and tha the other side of the battle were irrational crusaders with a serious reality-disconnect and reality-disinterest.

    The autopsy proves that the people claiming that Terri was awake, alive, concious, and most of all responsive were either lying, or more likely self deceiving about it. People sitting there watching Terri's body breath and blink and twitch autonomically who convined themselves that some random blink or twitch was a meaningful concious reply to their questions and actions... convincing themselves and deluding themselves because they so desperately wanted to beleive, people who so desperately wanted to ignore and dismiss all of the facts of reality, people who so desperately wanted to ignore and reject the science and all the evidence.

    I'm sorry to beat this horse to death, but the only organ that mattered, the thinking brain, was completely gone. Period. End of story. Gone. It is unbeleivable how many people are in such denial about that fact. No thinking brain tissue means no mind and no person and no possibility there was any concious response to anything.

    And it's obscene that politicians and activists took this sad sad case and turned it into a circus and political football. That people took this sad sad case and abused it for their peorsonal political aggrandizement.

    -

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