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Submission + - The Facebook loophole that lets world leaders deceive and harass their citizens (theguardian.com)

schwit1 writes: The investigation shows how Facebook has allowed major abuses of its platform in poor, small and non-western countries in order to prioritize addressing abuses that attract media attention or affect the US and other wealthy countries. The company acted quickly to address political manipulation affecting countries such as the US, Taiwan, South Korea and Poland, while moving slowly or not at all on cases in Afghanistan, Iraq, Mongolia, Mexico and much of Latin America.

“There is a lot of harm being done on Facebook that is not being responded to because it is not considered enough of a PR risk to Facebook,” said Sophie Zhang, a former data scientist at Facebook who worked within the company’s “integrity” organization to combat inauthentic behavior. “The cost isn’t borne by Facebook. It’s borne by the broader world as a whole.”

Facebook pledged to combat state-backed political manipulation of its platform after the historic fiasco of the 2016 US election, when Russian agents used inauthentic Facebook accounts to deceive and divide American voters.

But the company has repeatedly failed to take timely action when presented with evidence of rampant manipulation and abuse of its tools by political leaders around the world.

Submission + - How a Researcher 'Clinging to the Fringes of Academia' Helped Develop a Covid-19 (nytimes.com) 1

destinyland writes: The New York Times tells the story of Hungarian-born Dr. Kariko, whose father was a butcher and who growing up had never met a scientist — but knew they wanted to be one. Despite earning a Ph.D. at Hungary's University of Szeged and working as a postdoctoral fellow at its Biological Research Center, Kariko never found a permanent position after moving to the U.S., "instead clinging to the fringes of academia."

Now 66 years old, Dr. Kariko is suddenly being hailed as "one of the heroes of Covid-19 vaccine development," after spending an entire career focused on mRNA, "convinced mRNA could be used to instruct cells to make their own medicines, including vaccines."

Submission + - Former CDC director believes SARS-CoV-2 originated in lab 1

Beeftopia writes: Former CDC Director Robert Redfield told CNN on Friday that he believes the coronavirus "escaped" from the Wuhan Institute of Virology, and that it was spreading as early as September or October of 2019 — though he stressed that it was his "opinion."

"It's not unusual for respiratory pathogens that are being worked on in a laboratory to infect the laboratory worker. ... That's not implying any intentionality. It's my opinion, right? But I am a virologist. I have spent my life in virology," he continued.

Lab accidents in the U.S. are not especially rare, as USA Today's Alison Young noted in a recent opinion piece arguing why the Wuhan lab theory cannot be ruled out. The CDC itself experienced a possible contamination in a lab where it was making COVID-19 test kits early in the pandemic.

Redfield is a career virologist. He received his medical degree from Georgetown University before conducting his residency at the Walter Reed Army Medical Center as a US Army officer. Both of his parents were scientists at the National Institutes of Health. Before starting his position as the director of the CDC, Redfield was a professor at the University of Maryland School of Medicine and was once one of the US Army's leading AIDS researchers.

He does have a controversial incident regarding an AIDS vaccine on which his lab was working. He is accused of overstating its efficacy to gain funding.

Submission + - Scientists discover how humans develop larger brains than other apes (phys.org)

fahrbot-bot writes: A new study is the first to identify how human brains grow much larger, with three times as many neurons, compared with chimpanzee and gorilla brains. The study, led by researchers at the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, UK, identified a key molecular switch that can make ape brain organoids grow more like human organoids, and vice versa.

During the early stages of brain development, neurons are made by stem cells called neural progenitors. These progenitor cells initially have a cylindrical shape that makes it easy for them to split into identical daughter cells with the same shape.

The more times the neural progenitor cells multiply at this stage, the more neurons there will be later. As the cells mature and slow their multiplication, they elongate, forming a shape like a stretched ice-cream cone.

Previously, research in mice had shown that their neural progenitor cells mature into a conical shape and slow their multiplication within hours.

They found that in gorillas and chimpanzees this transition takes a long time, occurring over approximately five days.

Human progenitors were even more delayed in this transition, taking around seven days. The human progenitor cells maintained their cylinder-like shape for longer than other apes and during this time they split more frequently, producing more cells.

This difference in the speed of transition from neural progenitors to neurons means that the human cells have more time to multiply. This could be largely responsible for the approximately three-fold greater number of neurons in human brains compared with gorilla or chimpanzee brains.

Submission + - Study shows some exoplanets may have greater variety of life than exists on Eart (sciencenewsnet.in)

durini writes: A new study indicates that some exoplanets may have better conditions for life to thrive than Earth itself has. “This is a surprising conclusion”, said lead researcher Dr Stephanie Olson, “it shows us that conditions on some exoplanets with favourable ocean circulation patterns could be better suited to support life that is more abundant or more active than life on Earth.”

The discovery of exoplanets has accelerated the search for life outside our solar system. The huge distances to these exoplanets means that they are effectively impossible to reach with space probes, so scientists are working with remote sensing tool such as telescopes, to understand what conditions prevail on different exoplanets. Making sense of these remote observations requires the development of sophisticated models for planetary climate and evolution to allow scientists to recognize which of these distant planets that might host life.

Presenting a new synthesis of this work in a Keynote Lecture at the Goldschmidt Geochemistry Congress in Barcelona, Dr Stephanie Olson (University of Chicago) describes the search to identify the best environments for life on exoplanets:

“NASA’s search for life in the Universe is focused on so-called Habitable Zone planets, which are worlds that have the potential for liquid water oceans. But not all oceans are equally hospitable–and some oceans will be better places to live than others due to their global circulation patterns”.

Olson’s team modelled likely conditions on different types of exoplanets using the ROCKE-3D software*, developed by NASA’s Goddard Institute for Space Studies (GISS), to simulate the climates and ocean habitats of different types of exoplanets.

“Our work has been aimed at identifying the exoplanet oceans which have the greatest capacity to host globally abundant and active life. Life in Earth’s oceans depends on upwelling (upward flow) which returns nutrients from the dark depths of the ocean to the sunlit portions of the ocean where photosynthetic life lives. More upwelling means more nutrient resupply, which means more biological activity. These are the conditions we need to look for on exoplanets”.

They modelled a variety of possible exoplanets, and were able to define which exoplanet types stand the best chance of developing and sustaining thriving biospheres.

Submission + - House Panel Issues Scathing Report On 'Entirely Preventable' Equifax Data Breach (thehill.com)

An anonymous reader writes: The Equifax data breach, one of the largest in U.S. history, was "entirely preventable," according to a new House committee investigation. The House Oversight and Government Reform Committee, following a 14-month probe, released a scathing report Monday saying the consumer credit reporting agency aggressively collected data on millions of consumers and businesses while failing to take key steps to secure such information. "In 2005, former Equifax Chief Executive Officer (CEO) Richard Smith embarked on an aggressive growth strategy, leading to the acquisition of multiple companies, information technology (IT) systems, and data," according to the 96-page report authored by Republicans. "Equifax, however, failed to implement an adequate security program to protect this sensitive data. As a result, Equifax allowed one of the largest data breaches in U.S. history. Such a breach was entirely preventable."

The report blames the breach on a series of failures on the part of the company, including a culture of complacency, the lack of a clear IT management operations structure, outdated technology systems and a lack of preparedness to support affected consumers. "A culture of cybersecurity complacency at Equifax led to the successful exfiltration of the personal information of approximately 148 million individuals," the committee staff wrote. "Equifax’s failure to patch a known critical vulnerability left its systems at risk for 145 days. The company’s failure to implement basic security protocols, including file integrity monitoring and network segmentation, allowed the attackers to access and remove large amounts of data." The Oversight staff found that the company not only lacked a clear management structure within its IT operations, which hindered it from addressing security matters in a timely manner, but it also was unprepared to identify and notify consumers affected by the breach. The report said the company could have detected the activity but did not have "file integrity monitoring enabled" on this system, known as ACIS, at the time of the attack.

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