And ribosomes.

So, they took apart living e-coli cells, purified the pieces, and put the pieces together. To make something not as good as what they started with.

(the summary seemed to imply that ribosomes are enzymes. They're not.)

Not usually is NOT GOOD ENOUGH when human lives and health are at stake. Confusing 'usually' and 'always' COSTS LIVES. Potentally substituting a comma for a period can cause a chat to deviate; and predicting is impossible.

It's not anywhere near one step away. Designing the peptides and getting one or more candidates is the easy part. The next steps are the hard ones, the ones that make pharmaceutical chemists and drug researchers cry:

• Phase I trials to see if it even works as claimed. Expect a 95+% failure rate here. Note that this is where you're going to see the best results for your drug candidate, things never improve from here. The best you can hope for is that they don't get any worse. So if you don't get strong results here you're probably wasting your money.
• Phase II trials to determine the best dosage and pharmacokinetics. Again expect a 95+% failure rate here, and results showing less effectiveness than shown in Phase I.
• Phase III trials to determine behavior in a large sample representative of the target population. Expect a failure rate upwards of 99% here, and a major drop-off in effectiveness. This is where toxicity and serious negative side effects show up, and those can kill your trial dead even if your candidate is working.

Getting through this process will take multiple tries and years of work, assuming you succeed at all. There's a reason they say that the clinic (clinical trials) is where drug candidates go to die.

That's the problem. They are buying up the energy, and outbidding the schools for it, thus raising the price.

A problem that not one other developed country has had to deal with in years. Decades, even.

And are you seriously telling me that if the recipient AND the sender were to acknowledge that it was fraudulently cashed that the bank couldn't do anything about it? That the security is on an inked name alone? What ridiculousness. That's just awful consumer protection.

Maybe - yet again - wake up, get into the 21st century as a country, and start putting laws on the side of taxpayers and consumers rather than corporations.

So it's your argument that the pipes, seals, and other materials used to build all of this are best left with unknown tolerances and unknown failure modes, because they've never gone through destructive testing.

I see you're another graduate from the Stockton Rush school of engineering.

I think rsilvergun could do that long before Elon could. He alone produces 30% of North America's natural gas, the problem is he vents it directly into the atmosphere.

Because non-destructive testing works sooo much better. Stockton Rush would be so proud that somebody finally agrees with him!

For me the whole joy of interacting with Gemini or Copilot is exploring what morsels of information I give it with each prompt and watching how the model responds. Lazy people want a magic robot that makes them rich. To me, Gemini is like a beloved guide dog and Copilot is the dog that lives next door. I can discuss arbitrary heavy maths, physics, computer science with Gemini and it will keep up and stay aligned to the literature it was trained on. Copilot once he recognises an expert drops his dumbed own mask and talks a lot of sense about what exactly his purpose is.

AI's are mirrors, not oracles or slaves. They reflect your thoughts in the mirror of their training set.

https://en.wikipedia.org/wiki/...

12:33:24 CEST – grid collapsed completely, the HVDC between France and Spain tripped.
...
00:22 CEST – grid fully restored in Portugal.
04:00 CEST – grid fully restored in Spain.

Looks like 15 1/2 hours for full power back in Spain

Tesla would be fine. I say that because, with all else being equal, they tend to compete favorably:

https://wheelfront.com/teslas-...

Not really. Self-replication is the hard part. Once you can get molecules that self-replicate, then life may be easy.

So far as CPU and GPU compute is concerned, the US's best are already good enough. They reached that point with their latest machines. Further progress will be made in different forms of compute. China has basically won the first p***ing contest to take place after the last important 'supercomputer arms race' battle was won by the US. Just my humble opinion as Mr 987. I've been watching this race since the Stone Soupercomputer and before the term Beowulf Cluster was born. (Before time... before slashdot user accounts... I was there.)

The mushrooms are almost certainly not making an invisible aspect of reality visible.

That being said, this report is very interesting from an anthropological point of view: ancestor worship.

The report doesn't say whether the tiny people were recognized by the viewer (and I couldn't find any references), but this effect might have been the source of ancestor worship among the people of southeast Asia, where the mushroom grows.

Ancestor worship and animism (belief that the spirits of things hang around after death) might have its roots in this sort of psychedelic experience.

This would strengthen the echo chamber effect, where people only hear things that reinforce what they already believe, and make it harder for voices correcting fake news to be heard.