Comment Re:I'm not convinced. (Score 1) 57
Precisely.
Precisely.
There are 1500 genes involved. As effects are likely not merely down to specific genes, but gene interactions, you're going to need a model that can handle 2^1500 different permutations. That's simply not something that is classifiable.
As far as gene therapies are concerned, since autism seems to involve combining elements of Neanderthal neurology with homo sapiens neurology, the obvious fix would be to add further Neanderthal genes where combinations are known to produce adverse effects.
What did you expect from an algorithm named after the Roman Empire?
Ah yes, it's the "I gave it thought for 2 seconds, and now I have a better solution than the people who've been thinking about it for decades even though it's not my job, area of expertise, I don't understand the problem anyway, and I am free of a litany of other considerations that apply" guy. Good work.
There are 1500 genes associated with autism and nobody has them all. This gives us 2^1500 different forms of the condition. So, yeah, more than one.
Autism is definitely a complex phenomenon. The number of people diagnosed today in the US is about the same as was being diagnosed in Europe 25 years ago, so no, I don't think anyone is jumping onto bandwagons, it's just Americans are being less stupid.
Let's consider history and debt. The economies of the world have passed through several stages. Prior to the gold standard things could only scale so far before it failed. The gold standard reintroduced stability and fostered even more international trade. The principle of the gold standard was to maintain the peg of a currency to gold. This worked really well up till world war one. Its weaknesses had started to become carat before that where the need for currency expansion could not be satisfied till the next unpredictable gold rush discovery. As a result under capitalized banks became at risk and eventually their were crises that led into world war 1 and utterly failed after it leading to the great depression
We got out of the Great Depression largely in part ti temporary suspension of the gold standard.
A new way of pegging currency emerged with the Brettin woods agreement. All countries would peg to the us dollars and use treasuries as the medium of international money transfer not gold. The us would remain on the gold standard because it could afford to buy gold with all those treasury purchases.
But eventually this too saturated and limited growth. Under Nixon the us left the good standard.
The goal of the fed central bank was not to maintain the dollar per se since the dollar stood alone as the international benchmark. But instead the goal of the Fed was to curb inflation and curb unemployment. The weakness is the Fed only can use monetary policy not fiscal policy. As a result those two goals are in conflict since they cannot be decoupled with a single point of control ( monetary policy without fiscal policy)
But somehow we've done a great job using that system.
But now the international system has again scaled to a new problem which is deficit spending is reaching a point where debt service is a burden.
The next evolution of this is well known. It was beta tested in The depression when the us both went off the gold standard briefly but also excersized both monetary policy abs fiscal policy in concert.
The approach is called modern monetary theory. It has its critics but critics fixate on sound bite summaries of mmt and really fail to grasp that actually it not only can work but has worked in all the instances it has been tried ( us, Italy, Venezuela all recovered from crises under mmt approaches)
The fact that Europe is having problems is in fact due to the euro not allowing fiscal policy since states can't control their own money supply any longer.
The Fed not true problem with mmt is tgat one cannot actually trust politicians to conduct proper discipline in fiscal policy. That has to be solved before it can be implemented. What allowed its implementation in the past was the automatic and not political and transient spending needed to meet crises like the Great Depression. But to do it outside of unemployment periods is dangerous unless it can be done by an apolitical entity -- something similar to the Fed but with different powers and madates.
In any case the bottom line is this, under mmt a debt equal to your gdp is not a bad thing! No need to panic.
The economies of the world have passed through several stages. Prior to the gold standard things could only scale so far before it failed. The gold standard reintroduced stability and fostered even more international trade. The principle of the gold standard was to maintain the peg of a currency to gold. This worked really well up till world war one. Its weaknesses had started to become carat before that where the need for currency expansion could not be satisfied till the next unpredictable gold rush discovery. As a result under capitalized banks became at risk and eventually their were crises that led into world war 1 and utterly failed after it leading to the great depression
We got out of the Great Depression largely in part ti temporary suspension of the gold standard.
A new way of pegging currency emerged with the Brettin woods agreement. All countries would peg to the us dollars and use treasuries as the medium of international money transfer not gold. The us would remain on the gold standard because it could afford to buy gold with all those treasury purchases.
But eventually this too saturated and limited growth. Under Nixon the us left the good standard.
The goal of the fed central bank was not to maintain the dollar per se since the dollar stood alone as the international benchmark. But instead the goal of the Fed was to curb inflation and curb unemployment. The weakness is the Fed only can use monetary policy not fiscal policy. As a result those two goals are in conflict since they cannot be decoupled with a single point of control ( monetary policy without fiscal policy)
But somehow we've done a great job using that system.
But now the international system has again scaled to a new problem which is deficit spending is reaching a point where debt service is a burden.
The next evolution of this is well known. It was beta tested in The depression when the us both went off the gold standard briefly but also excersized both monetary policy abs fiscal policy in concert.
The approach is called modern monetary theory. It has its critics but critics fixate on sound bite summaries of mmt and really fail to grasp that actually it not only can work but has worked in all the instances it has been tried ( us, Italy, Venezuela all recovered from crises under mmt approaches)
The fact that Europe is having problems is in fact due to the euro not allowing fiscal policy since states can't control their own money supply any longer.
The Fed not true problem with mmt is tgat one cannot actually trust politicians to conduct proper discipline in fiscal policy. That has to be solved before it can be implemented. What allowed its implementation in the past was the automatic and not political and transient spending needed to meet crises like the Great Depression. But to do it outside of unemployment periods is dangerous unless it can be done by an apolitical entity -- something similar to the Fed but with different powers and madates.
In any case the bottom line is this, under mmt a debt equal to your gdp is not a bad thing! No need to panic.
By signaling that everyday/mundane content might hurt you, you teach people (teens and young adults in particular) that they are inherently fragile.
The problem is that life is tough. Even in rich Western social democracies, you will encounter horrible days and incredible challenges. Instead of coddling people and encouraging them to runaway from discomfort, we should be challenging them to engage with progressively more difficult ideas and realities.
Trigger warnings generally do more harm than good:
https://www.sciencefocus.com/t...
I love that you couldn't explain that without saying that they represent a financial opportunity rather than just, you know, solve a problem better than existing solutions.
They could also fire you for living out of a car. Fun choices!
If human activity was on a fixed time, that point in time could never be visible to astronomers, at least not unless LIGO was rebuilt on the moon. This doesn't necessarily offer benefits, but it would be sensible if this was a possibility that was considered.
True, it means we can't use gravitational triangulation, but the detector is nothing like close enough to being sensitive enough to be useful there.
Either way, between radio astronomy, optical astronony, and gravitational astronomy now being largely defunct on Earth due to humans messing things up, we really need detectors on the moon or on Mars before we can do anything significantly beyond what we've already done. Space telescopes are just too small and although you could precisely measure 3D positions with sufficient precision to do interferometry, it would not be easy.
Basically, each space telescope would need to measure acceleration with incredible sensitivity and time with incredible precision, record over a very long time, then have a means of collecting the data on physical media and bring it back to Earth for combining with the other recordings. Real-time interferometry wouldn't be possible.
You're much much better off building your telescopes on the surface of a solid planetary mass like the moon or Mars.
"It's my cookie file and if I come up with something that's lame and I like it, it goes in." -- karl (Karl Lehenbauer)