Submission + - Well, shit.
Cpt_Kirks writes: Patrick Stewart dead at 86.
Submission + - Bank of America kindly asks that you don't share your password with your AI asst (techcrunch.com)
schwit1 writes: In an email blast to customers titled “Protecting your finances in the Al World,” Bank of America urged customers to never share their username and password with another person or an outside service, “including an Al-enabled tool or agent that offers to act on your behalf.”
You can practically sense the frustration in the person sending the email. Still, customers are increasingly handing over their log-ins as personal AI assistants grow more popular. Sharing your banking username and password with an AI assistant runs the risk that it could do something with your finances without your knowledge, or that your bank thinks someone’s raiding your account and locks you out of it. Worse, a security flaw in the AI assistant could result in it leaking your banking credentials elsewhere, giving financially motivated hackers a way into your bank account.
You can practically sense the frustration in the person sending the email. Still, customers are increasingly handing over their log-ins as personal AI assistants grow more popular. Sharing your banking username and password with an AI assistant runs the risk that it could do something with your finances without your knowledge, or that your bank thinks someone’s raiding your account and locks you out of it. Worse, a security flaw in the AI assistant could result in it leaking your banking credentials elsewhere, giving financially motivated hackers a way into your bank account.
Submission + - This frog bacterium wiped out cancer tumors in mice with a single dose (sciencedaily.com)
fahrbot-bot writes: Science Daily has reported that scientists at the Japan Advanced Institute of Science and Technology (JAIST) have identified a naturally occurring bacterium from the intestines of Japanese tree frogs (Dryophytes japonicus) that demonstrated remarkable anticancer activity in mice. The findings, published in Gut Microbes, introduce a new approach to cancer treatment that uses living bacteria to directly target tumors rather than simply altering the gut microbiome.
In a mouse model of colorectal cancer, a single intravenous dose of E. americana completely eliminated tumors, producing a 100% complete response (CR) rate. The researchers emphasize that these findings are limited to mice, but they believe the results provide an encouraging proof of concept for developing new bacterial cancer therapies.
First, E. americana directly attacks tumors. As a facultative anaerobic bacterium, it thrives in both oxygen rich and oxygen poor environments, allowing it to multiply inside the oxygen deprived regions commonly found within tumors. Once there, the bacterial population increased by roughly 3,000 fold within 24 hours after treatment, directly damaging cancer cells.
Second, the bacterium stimulates the immune system. Its presence attracted T cells, B cells, and neutrophils into tumors. These immune cells then released inflammatory signaling molecules, including TNF- and IFN-, which strengthened the immune response and promoted cancer cell death.
One of the most striking findings was that E. americana accumulated almost exclusively inside tumors and did not colonize healthy organs.
They found that the bacteria were rapidly cleared from the bloodstream, with a half life of approximately 1.2 hours, and became undetectable within 24 hours. No bacterial colonization was detected in healthy organs, including the liver, spleen, lungs, kidneys, or heart.
The treatment caused only mild, temporary inflammation that returned to normal within 72 hours. During a 60 day observation period, the researchers found no evidence of chronic toxicity.
In a mouse model of colorectal cancer, a single intravenous dose of E. americana completely eliminated tumors, producing a 100% complete response (CR) rate. The researchers emphasize that these findings are limited to mice, but they believe the results provide an encouraging proof of concept for developing new bacterial cancer therapies.
First, E. americana directly attacks tumors. As a facultative anaerobic bacterium, it thrives in both oxygen rich and oxygen poor environments, allowing it to multiply inside the oxygen deprived regions commonly found within tumors. Once there, the bacterial population increased by roughly 3,000 fold within 24 hours after treatment, directly damaging cancer cells.
Second, the bacterium stimulates the immune system. Its presence attracted T cells, B cells, and neutrophils into tumors. These immune cells then released inflammatory signaling molecules, including TNF- and IFN-, which strengthened the immune response and promoted cancer cell death.
One of the most striking findings was that E. americana accumulated almost exclusively inside tumors and did not colonize healthy organs.
They found that the bacteria were rapidly cleared from the bloodstream, with a half life of approximately 1.2 hours, and became undetectable within 24 hours. No bacterial colonization was detected in healthy organs, including the liver, spleen, lungs, kidneys, or heart.
The treatment caused only mild, temporary inflammation that returned to normal within 72 hours. During a 60 day observation period, the researchers found no evidence of chronic toxicity.
Comment Re:Never will (Score 1) 131
I'm sure that someone is running an AI agent on Office right now. Word and Excel are the real enemies of switching.
Comment Re:Compatibility is always going to be a problem.. (Score 1) 131
Simply stating: We Do Not Accept DOCx or XLSx formats, forces compliance. Since MS can produce ODF (allegedly), that's how you get compliance.
Comment Re:It's funny (Score 2) 131
Excel isn't done until the macros won't run (on anything else).
Comment Re:It's funny (Score 1) 131
My father in law used to do design work in Excel. No kidding. He claimed Publisher et al didn't give him the precision he wanted, or something like that. It was amazing what he could put together in Excel.
Submission + - Blue Chip - fully US supply chain laptop (anduril.com)
fadethepolice writes: Anduril, arguing that its manuftacuring capabilities are directly applicable to laptop manufacturing is starting a project for a fully 100 percent US sourced laptop. The computer will use a Qualcomm snapdragon SOC. I did not see any information for the OS, but I'm assuming with the type of processor this will be Linux based?
Comment Eventually, what? (Score 1) 138
Will the employee base at companies like Microsoft eventually consist of a bunch of AI agents? With the General Counsel being the sole human, retained for legal purposes?
Comment Re:Just datacenters? (Score 0) 108
Why would I do that? Shouldn't there be at least minimal Government oversight?
Oh wait, now I get it, this is "racist" or something. We can't have oversight that would leave businesses without the under the table wages Americans won't work for.
Comment Re:Following the Trump playbook (Score 0) 79
Because one thing is exactly the same as the completely unrelated thing, except topically. That's why.
Comment There is no good marker for the "age" of a cell. (Score 2) 22
There is no good marker for the "age" of a cell.
Google result:
Key Methods Used to Estimate Cellular and Biological Age
https://www.google.com/search?...
Google result:
Key Methods Used to Estimate Cellular and Biological Age
https://www.google.com/search?...
Submission + - Will AI expose the rickety infrastructure of the internet? (techcrunch.com)
sziring writes: A startling announcement went out earlier this week: Due to recently discovered vulnerabilities in the open source programming language PHP, website owners had to immediately patch their sites â" or if they couldnâ(TM)t update right away, they should take the sites down to be safe.
On this weekâ(TM)s episode of TechCrunchâ(TM)s Equity podcast, Kirsten Korosec, Sean Oâ(TM)Kane, and I discussed the significance of the PHP-ocalypse and whether weâ(TM)ll see more incidents like this in the future.
Sean called this âoea real reckoning momentâ that highlights how âoewhen you get down to the bone level of the internet,â everything seems to be âoeheld together by glue and dreams.â And with widespread access to large language models and AI agents, itâ(TM)s only going to become easier to find these vulnerabilities. (That said, these specific vulnerabilities were found by human researchers, not AI models.)
Kirsten, meanwhile, wondered if weâ(TM)re about to see the âoenext level of prepper doom [â¦] because you could see how banks could get exploited, and [with] data and privacy concerns, it just feels a lot bigger than we can fix right now.â
Keep reading for a preview of our conversation, edited for length and clarity.
Sean Oâ(TM)Kane: The internet is breaking in lots of ways this week, it seems.
I think the best way to think about this, if people are coming into this kind of cold: How many times over the last 10 years have we had these moments where something breaks or something nearly breaks, where one person maintaining one tiny repro repository as a hobby or whatever happens to catch that something nefarious is going on and and saves us from the infrastructure of the internet completely crumbling?
Now multiply that by a billion, when people have access to not only extremely advanced software in the form of these LLMs that everybody uses, but also the ability to task them to go out and do it themselves, with creating AI agents that are single-minded at accomplishing those things.
Weâ(TM)re seeing a balance of two things happening this week. One is a bunch of the labs and companies like Google and OpenAI actually had people go out and find a bunch of vulnerabilities, including the one with PHP. And then we also have a bunch of people seeming to rush to take advantage of those vulnerabilities to try and hack into websites. So we have governments taking down websites, we have really popular websites that are going down briefly to be able to fix this vulnerability.
This is a real reckoning moment, where weâ(TM)re going to find out the downside risk of building so much of the internet on open source technology like PHP. When you really get down to the bone level of the internet, it is held together with glue and dreams.
On this weekâ(TM)s episode of TechCrunchâ(TM)s Equity podcast, Kirsten Korosec, Sean Oâ(TM)Kane, and I discussed the significance of the PHP-ocalypse and whether weâ(TM)ll see more incidents like this in the future.
Sean called this âoea real reckoning momentâ that highlights how âoewhen you get down to the bone level of the internet,â everything seems to be âoeheld together by glue and dreams.â And with widespread access to large language models and AI agents, itâ(TM)s only going to become easier to find these vulnerabilities. (That said, these specific vulnerabilities were found by human researchers, not AI models.)
Kirsten, meanwhile, wondered if weâ(TM)re about to see the âoenext level of prepper doom [â¦] because you could see how banks could get exploited, and [with] data and privacy concerns, it just feels a lot bigger than we can fix right now.â
Keep reading for a preview of our conversation, edited for length and clarity.
Sean Oâ(TM)Kane: The internet is breaking in lots of ways this week, it seems.
I think the best way to think about this, if people are coming into this kind of cold: How many times over the last 10 years have we had these moments where something breaks or something nearly breaks, where one person maintaining one tiny repro repository as a hobby or whatever happens to catch that something nefarious is going on and and saves us from the infrastructure of the internet completely crumbling?
Now multiply that by a billion, when people have access to not only extremely advanced software in the form of these LLMs that everybody uses, but also the ability to task them to go out and do it themselves, with creating AI agents that are single-minded at accomplishing those things.
Weâ(TM)re seeing a balance of two things happening this week. One is a bunch of the labs and companies like Google and OpenAI actually had people go out and find a bunch of vulnerabilities, including the one with PHP. And then we also have a bunch of people seeming to rush to take advantage of those vulnerabilities to try and hack into websites. So we have governments taking down websites, we have really popular websites that are going down briefly to be able to fix this vulnerability.
This is a real reckoning moment, where weâ(TM)re going to find out the downside risk of building so much of the internet on open source technology like PHP. When you really get down to the bone level of the internet, it is held together with glue and dreams.
Comment Re: Holy Unintended Consequences, Batman! (Score 1) 66
Don't give them ideas... Now that the market has surfaces a resource, the elites may start looking at wolves blood now - the wolverine stack.
Comment On-prem is back in an uncertain world. (Score 1) 173
Just in the last 24 months, Gulf, Iranian, Ukrainian and Russian cloud DCs have been targeted, including different availability zones of the same cloud vendor. So I think it's time corporates and governments start re-recognising the benefits of on-prem data centres. Yes, the old, distributed office-building DCs: halon fire suppression, lit/dark fibre, AC, cooling, giant boxy UPSs and captive power generation - all that. What makes it better now is that computers have gotten a lot more efficient (e.g., die shrinks, ARM solutions), while compute demands of most core business processes hasn't changed (I consider most AI loads are NOT truly 'keeps the business going' core. More like icing on a cake)
