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+ - Profits! Profits! Profits! Ballmer Says Amazon Isn't a Real Business

Submitted by theodp
theodp (442580) writes "According to Steve Ballmer, is not a real business. “They make no money,” Ballmer said on the Charlie Rose Show. “In my world, you’re not a real business until you make some money. I have a hard time with businesses that don’t make money at some point.” Ballmer’s comments come as Amazon posted a $437 million loss for the third quarter, disappointing Wall Street. "If you are worth $150 billion," Ballmer added, "eventually somebody thinks you’re going to make $15 billion pre-tax. They make about zero, and there’s a big gap between zero and 15." Fired-up as ever, LA Clippers owner Ballmer's diss comes after fellow NBA owner Mark Cuban similarly slammed IBM, saying Big Blue is no longer a tech company (Robert X. Cringely seems to concur). "Today, they [IBM] specialize in financial engineering," Cuban told CNBC after IBM posted another disappointing quarter. "They're no longer a tech company, they are an amalgamation of different companies that they are trying to arb[itrage] on Wall Street, and I'm not a fan of that at all.""

+ - More brainlessness from Ebola experts and government operatives

Submitted by schwit1
schwit1 (797399) writes "A doctor, having just returned from Guinea where he was frequently exposed to ebola, wandered about New York City for days, thus ignoring government protocols that required him to limit his contact with outsiders.

Lo and behold, 9 days after his return he is diagnosed with Ebola.

However, this isn't the worst of it. The police, after securing the doctor's apartment, removed their gloves and masks used to protect them and dumped them in an ordinary street trash container on a public street."

Comment: Should be VERY USEFUL for gene & stem cell the (Score 1) 45

by Ungrounded Lightning (#48226945) Attached to: Detritus From Cancer Cells May Infect Healthy Cells

This should be REALLY USEFUL - for gene therapy and stem cell therapy.

One of the big problems with such therapies is how to deliver the modified genes or regulators to the target cells, without converting them to something that would be rejected or otherwise have unintended markers or modifications.

One approach is to deliver genes or regulatory chemicals via a modified virius or using viral capsid proteins to construct an "injector". (A family of methods for turning harvested somatic cells into toti/pluri/multi/unipotent stem cells consists of inserting four regulatory proteins - by inserting about four GENES THAT CODE FOR THEM via a modified virus.)

Now here we have a a method, already used by the body, to transport RNA signalling snippets and other factors from one cell into another, by a sending cell creating virus-like carrier particles that destination cells readily accept and absorb.

THAT looks like an IDEAL basis for building a carrier for regulatory factors to switch cell modes on and off, or to tote new genetic material into a target cell for incorporation, to correct genetic errors or supply lost genes:

  1) Make fake exosomes carrying the message you want to deliver.
  2) Inject them into the tissue you want to affect.
  3) Rewrite the state or code of the target cells.
  4) Cure disease (or otherwise augment the patient's health).
  5) PROFIT!

Comment: But I bet it's descended from a virus. (Score 1) 45

by Ungrounded Lightning (#48226881) Attached to: Detritus From Cancer Cells May Infect Healthy Cells

Viruses by definition contain genetic code from outside the host organism.

On the other hand, just as some organelles (i.e. mitochondria, chloroplasts) are apparently the remnant of a microbial infection or ancient symbiosis that became integrated, there are several cellular mechanisms that are apparently remnants of an ancient retrovirus infection, where the bulk of the viral genome was lost but one of its mechanisms was retained and adapted to perform some useful new function.

I'd be willing to bet this is another example of such an

Comment: Not necessarily. (Score 1) 45

by Ungrounded Lightning (#48226835) Attached to: Detritus From Cancer Cells May Infect Healthy Cells

No, you'd have to be inbred with the cancer 'donor' to not reject their cancer as readily as you'd reject an organ transplant from them.

Not necessarily.

These things aren't carrying the full-blown genome. They're carrying little bits of it - like regulatory switches (or something that functions like that). They ought to be able, occasionally, to covert another person's cells JUST FINE without also marking them as any more foreign than an equivalent cancer naturally arising in that person.

+ - Verizon Injects Unique IDs into HTTP Traffic

Submitted by Anonymous Coward
An anonymous reader writes "Verizon Wireless, the nation's largest wireless carrier, is now also a real-time data broker. According to a security researcher at Stanford, Big Red has been adding a unique identifier to web traffic. The purpose of the identifier is advertisement targeting, which is bad enough. But the design of the system also functions as a 'supercookie' for any website that a subscriber visits."

Comment: And now the opposite view. (Score 2) 447

by khasim (#48224197) Attached to: Employers Worried About Critical Thinking Skills

Way too many people don't realize that our current economic and political system would not survive if critical thinking skills became commonplace.

Possibly. Although the same can be said of every other economic and political system as well. Which is a bit of a problem. People are messy. And each person has his/her own priorities and beliefs and weirdness.

We are destroying our own planet in the name of making 0.01% wealthy, and most of us, most of the time, are perfectly content to participate in the process in any way that pays decently and offers "interesting" work.

Just because someone exercises critical thinking does not mean that that person will come to the same conclusions that you have. They probably aren't starting with the same objectives as you.

Which is why companies DO NOT WANT real critical thinking skills.

They want people who think like they do and who come to the same conclusions that they do based upon the same information that they have.

Comment: Re:When you are inside the box ... (Score 1) 270

by bigpat (#48221693) Attached to: Assange: Google Is Not What It Seems
I agree to the extent that America has never lived up to its ideals. With a history of mass slavery, genocide and ethnic cleansing against native Americans, suppression of the press, book burning, oppression of women which are all things that are contrary to the ideals of Liberty and democracy. Where others only see the hypocrisy and the corruption of those ideals, I see a nation which is trying to maintain those ideals of Liberty and become better at their practice. The important thing about America is that its ideals of Liberty and Democracy are worth believing in and fighting for. That we don't always, or even usually, live up to those ideals is disheartening. Whatever your take on the current state of America, we all need to be better at telling the difference between rhetoric and reality, but that doesn't mean we become cynical about our own ideals. It just means when we fall short we try harder.

Comment: Re:Computer Missues Act 1990 (Score 5, Insightful) 508

by khasim (#48220231) Attached to: FTDI Removes Driver From Windows Update That Bricked Cloned Chips

And even without the law it seems fairly simple.

You do not INTENTIONALLY break equipment that you do not own. You do not do that. No matter how you feel about that equipment. Particularly when the person who now owns said equipment has no idea that there is a problem.

And I'd be wary of any company that could not understand that.

Comment: Re:I guess you missed Kent State? (Score 5, Insightful) 139

by khasim (#48219361) Attached to: Incapacitating Chemical Agents: Coming Soon To Local Law Enforcement?

Non-lethal weapons would allow protestors to protest without getting killed.

Protestors should be able to protest WITHOUT the police using either lethal or non-lethal weapons against them.

The important thing here is to take away the governments ability to kill.

Except that you are not doing that.

You are providing the police with pain-compliance (aka "torture") devices.

And as can be seen in many news reports, once the police/government has them, they will use them. And that use will not be INSTEAD of more lethal options. They will be used when the victims do not IMMEDIATELY follow the orders of the police. Even if those orders are illegal to begin with.

Those weapons will be treated as a "force multiplier". Not as a preferred option over lethal force.

Comment: Are you too happy? Facebook is the answer. (Score 1) 253

by Futurepower(R) (#48217833) Attached to: We Need Distributed Social Networks More Than Ello

Who needs social networks online?

Facebook solves a very serious problem. Are you too happy? Is it uncomfortable being happier than everyone else? Facebook is the answer. Read Facebook use predicts declines in happiness, new study finds. Or download the scientific paper.

+ - Google might poach Windows Phone's biggest app developer->

Submitted by Molly McHugh
Molly McHugh (3774987) writes "Rudy Huyn is a French app developer and an avid fan of Windows Phone. Huyn has created more than 20 apps for Microsoft’s mobile operating system, and including mobile apps for Instagram, Snapchat, Vine, Wikipedia, 9gag, Secret, and Dropbox. He has also created his own apps like Fuse and TV Show. With a developer showing this much commitment, you’d think Microsoft would have taken notice and hired him. Not quite."
Link to Original Source

+ - Microsoft exec opens up about Research lab closure, layoffs->

Submitted by alphadogg
alphadogg (971356) writes "It's been a bit over a month since Microsoft shuttered its Microsoft Research lab in Silicon Valley as part of the company's broader restructuring that will include 18,000 layoffs. This week, Harry Shum, Microsoft EVP of Technology & Research, posted what he termed an "open letter to the academic research community" on the company's research blog. In the post, Shum is suitably contrite about the painful job cut decisions that were made in closing the lab, which opened in 2001. He also stresses that Microsoft will continue to invest in and value "fundamental research"."
Link to Original Source

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