This is some info regarding scleroderma that I have shared with my friend with scleroderma over the years. I suspect some relationship to Lupus. Maybe this can help someone.

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Take a look at this article on autoimmune diseases.
https://www.lifeextension.com/...
It suggests vitamin D and Omega-3s:

_The daily supplemental dose was 2,000 IU of vitamin D3 and 1,000 mg of omega-3 fatty acids._

https://journals.plos.org/plos...
Here the core paper behind this article. They induced and cured an MS- like condition in animals by deactivating something called an 'aryl hydrocarbon receptor' in T cells. The receptor makes T cells overactive. This is what triggers sclerosis
Interestingly
- the receptor is sensitive to hydrocarbons (petrol, benzene, dry cleaning, cleaning chemicals)
- the receptor is sensitive to blue and UV light (getting a sunburn or tan)
So this should help:
- removing sources of volatile hydrocarbons
- avoiding blue/UV light and substituting with red light therapy (which energises mitochondria)

This paper seems promising.
https://www.ncbi.nlm.nih.gov/p...
I believe skin sclerosis occurs in scleroderma, correct? This paper basically says UV light that's normally used to treat skin sclerosis may be too damaging to certain tissue components. Instead, Red Light therapy is a promising treatment for skin sclerosis as it does not have these side effects. The paper recommends investigating its use in treatment.

*Excerpts:*
_Ultraviolet (UV) phototherapy is a non-invasive modality that has been used to treat several diseases associated with skin fibrosis including morphea, systemic sclerosis, chronic graft versus host disease, and nephrogenic systemic fibrosis [5–7]. However, UV phototherapy causes thymidine dimer DNA damage that is associated with an increased incidence of skin cancers and premature photoaging [8–10]. In addition to these safety concerns, UV phototherapy units are often prohibitively expensive for home use and require fluorescent or incandescent bulbs that limit portability. Therefore, UV phototherapy requires frequent office visits that patients often find burdensome [11, 12]. In contrast, light-emitting diode-generated red light (LED-RL) phototherapy is a safe, non-invasive, inexpensive, and portable treatment that may be combined with existing treatment modalities. Furthermore, the visible red light spectrum has superior depth of penetration, when compared to UV light, that allows it to penetrate the epidermis and reach the dermis to affect fibroblast function [13]. LED-RL is not known to cause thymidine dimer DNA damage or to be associated with an increased incidence of skin cancer [14]. However, the underlying biochemical mechanisms and clinical effects of visible light photobiomodulation of skin fibrosis are not well characterized._

*_Conclusions_*
_Visible light phototherapy is an emerging therapeutic modality for treatment of skin fibrosis. There is a growing body of evidence demonstrating that visible red light is capable of modulating key cellular characteristic associated with skin fibrosis. We believe that further laboratory research may elucidate the underlying mechanisms and effects involved in visible light photobiomodulation. LED-based devices are the optimal devices for red visible light phototherapy. There is a current lack of clinical trials investigating the efficacy of LED-RL to treat skin fibrosis. Randomized clinical trials are needed to demonstrate visible red light’s clinical efficacy on different types of skin fibrosis._

"The technique, called transcutaneous auricular vagus nerve stimulation (tVNS), which involves electrical stimulation to the vagus nerve through the skin on the outer ear and can be done at home, also resulted in lower levels of IL-6, an inflammatory molecule with a known role in SSc"
  https://sclerodermanews.com/ne...

https://wholefamilyproducts.co...
There is a Japanese supplement called serrapeptase. It dissolves unwanted protein and is used by silkworms to free themselves from their cocoon.
It is useful for scleroderma.

  https://www.inspire.com/groups...
This thing called natto, a Japanese fermented soy food, may be good for you. See this enzyme extracted from it is "fibrolytic" - dissolves clots and scars.

https://chatgpt.com/share/67a7...
can you have a read of the attached AI session and then ask your specialist about rhubarb extract containing rhein?

This is a very interesting supplement. small amounts reboot mitochondria, and increase energy
https://youtu.be/qdN3q8MFJIM?s...

https://youtu.be/MBXBpm1Y5J0?s...
This seems useful: a video on diet in managing scleroderma. At 15:57 he makes a very interesting point that 50% of calories must come from Omega fats. He says carnivore diet helps by eliminating carbs that feed harmful gut bacteria. But he recommends the carnivore diet only during scleroderma flares. In the main, he recommends a customised 'phyto-diet' based on plant foods

https://youtu.be/vmBHj-5SUWY?s...
This video lists different useful natural supplements for Sjogren's syndrome - a somewhat related autoimmune disorder that overlaps with scleroderma 20% of the time. The recommendations here each target specific different pathologies and root causes (the CMV and EBV viruses). I feel these will be useful for you. He talks about supplements including wormwood and cordyceps mushrooms

My friend has Scleroderma and his mother died of lupus.
Both are auto-immune conditions . From what I read online, both conditions are somewhat related: "around 20% of people with scleroderma also have lupus as a cross-over condition or 'overlap syndrome'".

I wonder if both my friend and his mother had the same virus trigger their conditions

Yes, the problem with 'end-to-end encrypted traffic' is one end is the device, and the other end is the manufacturer. The supposed owner gets no look at the data 'his' device is sending

If (say) the bus services a naval base, very sensitive information may be transmitted (stop location, duration, schedule, internal fuel level...)

If only a strange hybrid of John Deere and Tesla built buses, those would not have this problem, right?

Right?

I don't know why large buyers, in particular, allow end-to-end encrypted traffic between the vendor and the products the buyer ostensibly owns.

At the very least, the traffic should be open to inspection by the buyer, who should be able to selectively turn off or disable aspects of it.

I agree completely. AIs can do that already. There are even some prompts supposed to enhance the interaction. Something like this:
  "You are an advanced so and so... You teach using the Socratic method".

Coupling AI to licensed course content chopped up for focussed instruction delivery will make it even more powerful. It should also reduce the chance of misinstruction or hallucination.

It can do a passable simulacrum of that :-).

Won't using 1Password - as opposed to using a local credential store - also risk compromise of the enterprise?

My impression of 1Password is that it is centralised store of encrypted passwords - isn't that a hacker magnet? Hackers could obtain the encrypted store and attempt to decrypt at leisure. Or hack 1Password's communication interfaces and endpoints.

I'd be much more comfortable if all 1Password did was enable the syncing of credential stores directly between devices, never keeping a copy . That way I gain a distributed master record. Basically, a signal to say "hey, a credential has changed; sync up with such and such device". If my devices happen to sync directly, the vendor may never even see an encrypted copy of my passwords, much less store it.

If a centralized master copy is essential, 1password should deploy software that centralizes credentials at the organisation level... The software should be owned by the customer. instead, right now the 1Password architecture has them hosting hundreds of millions of credentials on their servers. While the data is encrypted from their eyes, doesn't centralization make them a hacker magnet? Hackers could obtain encrypted stores with hundreds of millions of credentials and attempt to decrypt them at leisure. Or they focus their hacking efforts on 1Password's communication interfaces and endpoints. That make me queasy.

With 1 billion terminal sessions made per week to its mainframe cloud, IBM spins off its thriving hosted mainframe business. The IPO is valued at 1 Trillion dollars.

Then the microprocessor and PC revolution breaks.

In violation of "Federal anti-discrimination laws" seems to have been the key clause. It's unlikely you are in violation.

Why not have your lawyer list out all your DEI initiatives to the granting body and say "are you OK with this?". An OK by the granting makes it unlikely they can claw it back.

It should just disclose the data and put a disclaimer on how it disagree at the end of the report

If I want to learn (say), how to do Markov chain Monte Carlo methods, I need to scrounge around learning materials online, or signup for a Statistics degree.

  Why not create a framework for the user's AI to contact the university AI, formulate a learning plan involving university course content and past assignments, and maybe 3rd party content. A course tailored to the user like a well fitting suit, readied in seconds and costing a few bucks.

To convert the micro-courses to a micro-credential, the user pays a bit more and takes an online exam proctored by AI-monitored cameras.

Every technology that bosses think is useful, they pursue and *implement* by integrating it into their business process. So Ford implemented assembly lines for the Model T. Companies implemented virtual machines in data centers. Google implemented Kubernetes-like software across its internal operations (?)

Why is implementing AI technology your headache? Especially if the only interface you have is a prompt? Implementation is your boss's job.

I think certain development tools have integrated AI well. The business world, in general, has not.

AI too has its occasional hallucinations and general weirdness. So perhaps two independent AIs?

On a different note, AI cameras aren't everywhere. Perhaps, mobile AI camera (s).

Or two, body-worn, shoulder-mounted AI cameras+microphones that have full authority to independently change camera angle.

"A chip on each shoulder" :-)

"Combined with a form of fusion... the machines had found all the energy they would ever need."

Apparently, Amazon meetings have an empty chair. It is supposed to represent the customer in the room.

Do they now use the chair for 'Pin the tail on the donkey' games?

From personal experience, Prime video has become unusable after I refused their shakedown to pay extra to skip ads.