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Submission + - We Were Wrong - the Testes Are Connected to the Immune System (sciencealert.com)

An anonymous reader writes: Some parts of the body – including the tissues of the brain and testes – have long been considered to be completely hidden from our immune system.

Last year scientists made the amazing discovery that a set of previously unseen channels connected the brain to our immune system; now, it appears we might also need to rethink the immune system's relationship with the testes, potentially explaining why some men are infertile and how some cancer vaccines fail to provide immunity.

Researchers from University of Virginia School of Medicine discovered a 'very small door' which allows the testes to expose some of its antigens to the immune system without letting it inside.

For the past four decades the testes have been regarded as having 'immune privilege', meaning they don't mount an immune response when introduced to materials the immune system considers foreign.

Together with the brain, eyes, and placenta, inflammation in these parts of the body would be seriously bad news, which could explain why they are all physically or chemically hidden from the white cells and antibodies which protect us from infection.

The science WAS settled.

Comment Re:The self-driving car is blamed for human error (Score 1) 225

The problem is, statistics don't matter if an automated car kills someone in a situation that a human wouldn't have. One day if they are 100x safer, I would hope they would be safe in all situations that a human would be.

This is arguably why the FDA kills more than it saves. Who studies how many lives are saved by medical advancements and compares it to those saved by preventing bad medicine from getting to market. What is an extra 5 years on average of delaying good drugs vs. bad ones getting out too soon then stopped after they become a problem?

Nobody studies the tens of thousands dying because a heart med gets to market late vs. a few dozens who might die if it gets to market too soon.

Submission + - An Unexpected New Lung Function Has Been Found - They Make Blood (sciencealert.com) 1

schwit1 writes: Researchers have discovered that the lungs play a far more complex role in mammalian bodies than we thought, with new evidence revealing that they don't just facilitate respiration — they also play a key role in blood production.

In experiments involving mice, the team found that they produce more than 10 million platelets (tiny blood cells) per hour, equating to the majority of platelets in the animals' circulation. This goes against the decades-long assumption that bone marrow produces all of our blood components.

Researchers from the University of California, San Francisco also discovered a previously unknown pool of blood stem cells that makes this happen inside the lung tissue — cells that were incorrectly assumed to mainly reside in bone marrow.

"This finding definitely suggests a more sophisticated view of the lungs — that they're not just for respiration, but also a key partner in formation of crucial aspects of the blood," says one of the researchers, Mark R. Looney.

Submission + - Judge OK's Petition for America's First 'Genderless' Person (heatst.com)

schwit1 writes: Home Culture Wars By Jillian Kay Melchior | 12:33 pm, March 25, 2017 A Portland student has become the first American to gain legal designation as “genderless”, following a ruling by a Multnomah County judge.

The March 10 decision, reported for the first time on Thursday, involved a 27-year-old who was born male but claimed to identify with no gender whatsoever. Judge Amy Holmes, who approved the petition, also last year approved a “non-binary” gender designation for another Portland resident.

The 27-year-old formerly known as Patrick Abbatiello, now legally designated agender, also got legal approval to change names, now going only by “Patch,” no surname. That name also serves as a pronoun, Patch explained to the local NBC affiliate this week.

Comment Re:Given that Venezuela's economy is tanking (Score 1) 89

Did you type that on iPhone or android or PC? You would have none of that relying on communism, which institutionalizes the dictatorship you lambaste.

There is no such thing as real communism that has never been tried. It is a dictatorship at its core. People are not free to satisfy the needs or desires of others, so it will always lag and fail at even the basics.

Submission + - Foreign Students Say U.S. High School Classes Are Absurdly Easy (the-american-interest.com)

schwit1 writes: When the Brookings Institution’s Brown Center on Education Policy surveyed foreign exchange students studying in the U.S. in 2001, it found that they thought that American education was a cake walk compared to secondary education in their home countries. And when it conducted the survey again in 2016, it found that exchange students thought that U.S. education was even less challenging than before.

Submission + - SPAM: Peak oil? Sooner than you think

schwit1 writes: The London-based investment advisory firm Redburn thinks that global demand for oil could peak around 2026, writes Fereidoon Sionshansi, President of Menlo Energy Economics and publisher of the newsletter EEnergy Informer. The implications for oil majors are ominous.For some time, there has been speculation about when global oil demand may peak – not because we will run out of oil or prices will spike making oil unaffordable, notions that are now considered passé – but because we won’t be needing as much of the stuff as we thought we would. And once the peak is finally reached – whenever that is – demand will begin to drop thereafter, perhaps precipitously.
Link to Original Source

Submission + - SPAM: Double Filters Allow Tetrachromatic Vision in Humans.

schwit1 writes: “Humans have three types of cone cells in the back of the eye to differentiate color. Some react to blue, some to green and some to red. The cones do their work by responding to the difference in wavelength of the incoming light. Such vision is known as trichromatic. In this new effort, the researchers have found a way of fooling the brain into seeing as if there were a fourth type of cone, by wearing glasses with two types of filters. The result is tetrachromatic vision. . . . The filters remove some parts of the blue light spectrum. But the filters each remove a different part. When the filters are fitted into a frame and worn like regular glasses, the wearer is able to see colors that are normally hidden—metamers. In a sense, it is rather the opposite of what occurs with people who are color blind. They might see blue and red as the same, even though there is more light information there. Adding spectrum identification to color blind eyes allows for seeing more of what is already there. With the new combined filter system, a person is able to look at what appears to be an object that is all the same color, such as purple, and see more colors in it—those normally hidden metamers.”
Link to Original Source

Comment Re:Poor business (Score 1) 394

Back then he was right. Art in visual design is not art in expression of gameplay. Most games just repeated the same gamsplay over and over and over, changing a monster every 15 minutes of play.

He's still largely right today. A series of cut scenes played end to end might make for a shitty B movie, but that isn't a video game. That is a movie intertwined with one.

Let's make a new Plinkett/Bechtel type test right here. Describe artistic game expression without relying on irrelevant (to the medium) things like pretty backgrounds, models, or movie cut scenes.

Where is the gameplay beef?

Submission + - SPAM: Soviet cover-up of nuclear fallout worse than Chernobyl

schwit1 writes: It was a nuclear disaster four times worse than Chernobyl in terms of the number of cases of acute radiation sickness, but Moscow’s complicity in covering up its effects on people’s health has remained secret until now.

We knew that in August 1956, fallout from a Soviet nuclear weapons test at Semipalatinsk in Kazakhstan engulfed the Kazakh industrial city of Ust-Kamenogorsk and put more than 600 people in hospital with radiation sickness, but the details have been sketchy.

After seeing a newly uncovered report, New Scientist can now reveal that a scientific expedition from Moscow in the aftermath of the hushed-up disaster uncovered widespread radioactive contamination and radiation sickness across the Kazakh steppes.

The scientists then tracked the consequences as nuclear bomb tests continued — without telling the people affected or the outside world.

The report by scientists from the Institute of Biophysics in Moscow was found in the archive of the Institute of Radiation Medicine and Ecology (IRME) in Semey, Kazakhstan. “For many years, this has been a secret,” says the institute’s director Kazbek Apsalikov, who found the report and passed it on to New Scientist.

More nuclear bomb tests were conducted at Semipalatinsk than anywhere else in the world during the 1950s and early 1960s. Western journalists have reported since the breakup of the Soviet Union on the apparent health effects on villagers downwind of the tests. And some recent studies have estimated radiation doses using proxies such as radioactivity in tooth enamel.

The newly revealed report, which outlines “the results of a radiological study of Semipalatinsk region” and is marked “top secret”, shows for the first time just how much Soviet scientists knew at the time about the human-health disaster and the extent of the cover-up.

Link to Original Source

Comment Re:Huh? I use these all the time. (Score 1) 263

I have used close-to-right only once, a long time ago. Here are two similar things I currently often do:

1. Close all -- just click the little close box. Saves a few clicks over the close all tabs.

2. Close all but one -- grab the tab and pull it out into another window, then alt-tab back and click the close box on the previous window.

Easy, faster, and completely intuitive.

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