Start a new site called oldiefans

You only think that's not political because you're confusing centrists with leftists.

No, it's because of all the idiotic enablers. We could just solve the problem by walking into the halls of power en masse and removing them but you can only get that kind of energy from total fucking clowns who want anarchy, and not the good kind that doesn't exist (as it leads naturally to feudalism) but the bad kind with only chaos.

Web apps make at least some sense when you are delivering the exact same app via the web and as a local application. But Microsoft isn't doing that, so they make none...

In short, Java was invented for a reason, and while it has become a victim of legacy cruft as well, the underlying concept of truly portable apps, with a minimum of fuss to jump from platform to platform, still ought to be the preferable path. The problem is that that true platform neutrality/ambiguity pretty much kills Microsoft in all but a few niches, like gaming, but only because hardware vendors put less effort into drivers for other operating systems.

Yes, Office is still king, although I think that crown is beginning to slip, and it may end up being Excel, with its large list of features, that may last the longest. But it isn't 1990, or even 2000 anymore. Developers have multiple ways of developing portable applications, and while MS may (for the nth time) update or swap out its toolchains, the real question is will developers really care?

A bit more about the latter. Beyond organophosphates, the main other alternative is pyrethroids. These are highly toxic to aquatic life, and they're contact poisons to pollinators just landing on the surface (some anti-insect clothing is soaked in pyrethrin for its effect). Also, neonicotinoids are often applied as seed coatings (which are taken up and spread through the plant), which primarily just affect the plant itself. Alternatives are commonly foliar sprays. This means drift to non-target impacts as well, such as in your shelterbelts, private gardens, neighbors' homes, etc. You also have to use far higher total pesticide quantities with foliar sprays instead of systematics, which not only drift, but also wash off, etc. Neonicotinoids can impact floral visitors, with adverse sublethal impacts but e.g. large pyrethroid sprayings can cause massive immediate fatal knockdown events of whole populations of pollinators.

Regrettable substitution is a real thing. We need to factor it in better. And that applies to nanoplastics as well.

In this case it would be easy enough to calculate how much anything would be off and then use the existing data.

Remember we're not talking about science here we're talking about public policy. So yeah the scientists can go ahead and redo all the experiments just to confirm the numbers and that's something scientists will want to do.

But we're not going to find all of a sudden that micro plastics are good for you. Neither are we going to find that they are in such low quantities that they aren't harmful. At best this is going to slightly skew the results.

But this isn't like radiometric dating where there are are all sorts of caveats because of how that science works. At the end of the day you've still got a brain full of plastic it's just potentially slightly less plastic.

But as usual just like when cigarettes were discovered to be killing people the plastic industry is going to hammer us with stories about this and slow down and the attempt at reform for at least another 50 years. And just like the cigarette industry, assuming our civilization survives what's happening right now that is, our grandchildren and great-grandchildren are going to look back at this time and say what the fuck was wrong with those people?

So, when we say microplastics, we really mainly mean nanoplastics - the stuff made from, say, drinking hot liquids from low-melting-point plastic containers. And yeah, they very much look like a problem. The strongest evidence is for cardiovascular disease. The 2024 NEJM study for example found that for patients with above-threshold levels of nanoplastics in cartoid artery plaque were 4,5x more likely to suffer from a heart attack. Neurologically, they cross the brain-blood barrier (and quite quickly). A 2023 study found that they cause alpha-synuclein to misfold and clump together, a halmark of Parkinsons and various kinds of dementia. broadly, they're associated with oxidative stress, neuroinflammation, protein aggregation, and neurotransmitter alterations. Oxidative stress is due to cells struggling to break down nanoplastics in them. They're also associated with immunotoxicity, inflammatory bowel disease, and reproductive dysfunction, including elevating inflammatory markers, impairing sperm quality, and modulating the tumor microenvironment. With respect to reproduction, they're also associated with epigenetic dysregulation, which can lead to heritable changes.

And here's one of the things that get me - and let me briefly switch to a different topic before looping back. All over, there's a rush to ban polycarbonate due to concerns over a degradation product (bisphenol-A), because it's (very weakly) estrogenic. But typical effective estrogenic activity from typical levels of bisphenol-A are orders of magnitude lower than that of phytoestrogens in food and supplements; bisphenol-A is just too rare to exert much impact. Phytoestrogens have way better PR than bisphenol-A, and people spend money buying products specifically to consume more of them. Some arguments against bisphenol-A focus on what type of estrogenic activity it can promote (more proliferative activity), but that falls apart given that different phytoestrogens span the whole gamut of types of activation. Earlier research arguing for an association with estrogen-linked cancer seems to have fallen apart in more recent studies. It does seem associated with PCOS, but it's hard to describe it as a causal association, because PCOS is associated with all sorts of things, including diet (which could change the exposure rate vs. non-PCOS populations) and significant hormonal changes (which could change the clearance rate of bisphenol-A vs. non-PCOS populations). In short, bisphenol-A from polycarbonate is not without concern, but the concern level seems like it should be much lower than with nanoplastics.

Why bring this up? Because polycarbonate is a low-nanoplastic-emitting material. It is a quite resilient, heat tolerant plastic, and thus - being much further from its glass transition temperature - is not particularly prone to shedding nanoplastics. By contrast, its replacements - polyethylene, polypropylene, polyethylene terephthate, etc - are highly associated with nanoplastic release, particularly with hot liquids. So by banning polycarbonate, we increase our exposure to nanoplastics, which are much better associated with actual harms. And unlike bisphenol-A, which is rapidly eliminated from the body, nanoplastics persist. You can't get rid of them. If some big harm is discovered with bisphenol-A that suddenly makes the risk picture seem much bigger than with nanoplastics, we can then just stop using it, and any further harm is gone. But we can't do that with nanoplastics.

People seriously need to think more about substitution risks when banning products. The EU in particular is bad about not considering it. Like, banning neonicotinoids and causing their replacement by organophosphates, etc isn't exactly some giant win. Whether it's a benefit to pollinators at all is very much up in the air, while it's almost certain that the substitution is more harmful for mammals such as ourselves (neonicotinoids have very low mammalian toxicity, unlike e.g. organophosphates, which are closely related to nerve agents).

This is so true, so true.

And it's not even US specific. In the wake of the Ukraine war, German parliament voted to give itself 100 billion of additional taxpayer money (i.e. debt) to spend on defense. Recently a report came out of all the money spent so far, 90% did not go towards the intended purpose.

Why any of the jokers in charge of our governments are still not in jail baffles me more and more every year. Oh yes, it's because they make the rules, sorry, my bad.

That's what campaign donations get you, if they are large enough.

This is why congress occasionally bullies the big tech companies. We all think they might want to have some regulation or to punish them. Oh sweetie... they're saying "nice company you have there... would be a shame if something happened to it..."

The best time to leave github was when the evil empire bought it. The second best time is now.

Seriously. Anyone who thought MS wouldn't fuck it up in the same way they fuck up everything they touch can't be helped. It's Microsoft for crying out loud.

Thanks for making my point for me there bro

I'm going to go ahead and assume bad faith on your part, because otherwise you're very stupid. But nobody in your potential audience is stupid enough to believe there aren't lasting effects to being bombed to shit.

I take your point about this being before the dawn of ubiquitous tech companies, but what kind of chilling effect did the Bell monopoly have?

About losing those lawsuits. They can absorb the fines and work around them. After a little bit of finagling the dollar amounts involved will not be terribly large. But on the other hand, and they have called this out in their sec filings, this basically makes it borderline impossible for any competitor to go up against them. In the long run it's probably going to save them money because traditionally the way they survive is by buying up whichever competitor of theirs the kids under 15 flocked to in order to find a place their parents didn't hang out

It's like how Microsoft lost their antitrust trial and the "punishment" was to give away millions of dollars of software to schools which they had been trying to get to take their software for 20 years...

I don't know what the opposite of a pyrrhic victory but I believe we've found it.