Comment The public are as lazy at socializing... (Score 1) 38
....a Slashdot "editors" are at picking content.
Comment "Well loved'?? Who by? The Verge? (Score 1) 23
Turning off Pocket in Firefox is normal decluttering.
Submission + - Scientists Built Cancer Kill Switch That Turns On With Flash of Light (studyfinds.com)
fjo3 writes: Cancer has a dirty trick: it can put itself to sleep. When tumor cells slip into a kind of biological hibernation, they become hard to kill, shrugging off treatment and lying low until conditions improve, then waking up and bringing the disease back. For decades, researchers have struggled to shut down this hiding strategy without causing serious harm elsewhere in the body. A team in Switzerland has now built a molecule that flips on and off with flashes of light, giving scientists a precise new way to probe, and possibly disrupt, the way sleeping cancer cells hide.
Behind this cellular sleep state, at least in certain cancers, sits a protein called the glucocorticoid receptor, a sensor inside cells that reacts to stress hormones. When it switches on, it can push cancer cells, especially in some solid tumors such as lung cancer, into a drug-resistant, dormant state. The obvious fix would be to destroy the receptor outright, but there is a catch: the same receptor does important jobs all over the body, including calming inflammation. Removing it everywhere would cause real damage. What was needed was a way to hit the receptor inside a tumor and leave the rest of the body alone.
Behind this cellular sleep state, at least in certain cancers, sits a protein called the glucocorticoid receptor, a sensor inside cells that reacts to stress hormones. When it switches on, it can push cancer cells, especially in some solid tumors such as lung cancer, into a drug-resistant, dormant state. The obvious fix would be to destroy the receptor outright, but there is a catch: the same receptor does important jobs all over the body, including calming inflammation. Removing it everywhere would cause real damage. What was needed was a way to hit the receptor inside a tumor and leave the rest of the body alone.
Comment Re: How did this article even get published? (Score -1) 226
Maintaining the low quality of Slashdot is a mysterious choice by its owners whose replacement by AI would be an upgrade.
Comment Why does his age matter? (Score 1) 69
Why was it somehow important to state his age?
A young adult criminal should surprise no one even in this era of grotesquely extended childish behavior.
Comment Re:Wait, what? (Score 0) 186
It's important to realize that the so-called far-left Democrats idealize Bolshevism while the far-right Republicans idealize Fascism, both of which are forms of Big Government Socialism.
So if the Democrats are in power and they want to increase the size and scope of government the Republicans will go along with it 80% of the time. Because they know they will eventually be back in power and have more tools of power to control.
They will balk the other 20% of the time so they still have something to run on and false promises to make to their voters.
The base of both parties is mostly against all of this.
Submission + - Video Game History Foundation Says Piracy Remains the Only Preservation Method (techspot.com)
An anonymous reader writes: Video Game History Foundation founder Frank Cifaldi recently supported claims that piracy is the only effective way to preserve video games. The comments lay the blame squarely on game companies' refusal to keep legacy content available or allow archivists to build legal repositories. Sony's announcement that all PlayStation games will be digital-only from 2028 onward has sparked concern that titles will become harder to preserve and more easily vanish, since the company's servers will become the sole point of distribution. In an official statement, Cifaldi noted that the end of physical PlayStation games has surprisingly little impact on the Foundation's efforts because the majority of games from the last two decades are already digital-only.
According to the Foundation, most games nowadays are not released for consoles, let alone on physical discs. Furthermore, many discs for major titles require downloading updates before they are playable, although the DoesItPlay database reveals that, even today, most are playable offline out of the box. Cifaldi claimed that the true reason piracy remains the best option for preservation is that the Entertainment Software Association, which lobbies for game publishers, has closed off other routes. For example, in 2018, the Association opposed efforts to grant copyright exemptions for museums, libraries, and archives to retain copies of abandoned online games for research.
This is the same organization that recently helped defeat a proposed California bill to preserve premium-priced online-only games by falsely claiming that community servers are illegal. The Foundation accused the ESA of repeatedly blocking attempts by cultural heritage institutions to reform DRM legislation. Cifaldi also described the Library of Congress' outdated software preservation process, which currently only requires tiny snippets of source code. For example, Capcom once asked the Foundation to provide the LoC with "the first and last ten pages of code" for a Mega Man game. Unable to discern where digital records began and ended, the group simply chose random segments. Platform holders' habit of closing online storefronts and removing media from users' accounts is also unhelpful.
According to the Foundation, most games nowadays are not released for consoles, let alone on physical discs. Furthermore, many discs for major titles require downloading updates before they are playable, although the DoesItPlay database reveals that, even today, most are playable offline out of the box. Cifaldi claimed that the true reason piracy remains the best option for preservation is that the Entertainment Software Association, which lobbies for game publishers, has closed off other routes. For example, in 2018, the Association opposed efforts to grant copyright exemptions for museums, libraries, and archives to retain copies of abandoned online games for research.
This is the same organization that recently helped defeat a proposed California bill to preserve premium-priced online-only games by falsely claiming that community servers are illegal. The Foundation accused the ESA of repeatedly blocking attempts by cultural heritage institutions to reform DRM legislation. Cifaldi also described the Library of Congress' outdated software preservation process, which currently only requires tiny snippets of source code. For example, Capcom once asked the Foundation to provide the LoC with "the first and last ten pages of code" for a Mega Man game. Unable to discern where digital records began and ended, the group simply chose random segments. Platform holders' habit of closing online storefronts and removing media from users' accounts is also unhelpful.
Comment Re:Oh it's not feasable (Score 1) 186
That and Russia has suggested destroying the orbit if Starlink doesn't stop enabling terrorist attacks by NATO proxies on its people.
The AI cut-off dive bomb tactic is a blatant warcrime.
Comment Re:Oh it's not feasable (Score 2) 186
Space Data Centers are in the same category as fully autonomous self-driving cars within eighteen months that he 'promised' in 2019.
You can watch the 'Autonomy Day' video on YouTube. People financed Model 3's on the promise of renting them as robotaxis while they were at work.
Physics is a hard stop on false promises.
It's OK to back difficult challenges with no underlying physical impossibilities that's engineering. Radiating heat into space is a physics problem.
I didn't believe the robotaxi promise then and I don't believe the space data centers claim now.
If there's a new topological physics breakthrough then let's see the paper and get the Nobel Prize gears turning because that would revolutionize technology on and off planet.
I'd love to see it but I don't believe it.
Comment Risky Business (Score 4, Interesting) 89
Reddit isn't wrong about bots but odds are what they really want is your identity. That earns money.
The trouble is people in Saudi Arabia will use old. to read about liberation topics or people in the US will read about drug topics, or whatever the mala prohibita are that will land you in prison for things that are perfectly legal in other jurisdictions.
Even people with accounts who read other subs logged in.
"Just create a new anonymous account" is what people will say who don't understand how identity correlation works. Sure there are ways that 0.0000001% of the population can manage securely, but that's not how this will go down.
The UK just arrested an American attorney who was critical of UK politics and they have multiple people in prison for clicking 'Like'. If you think they won't arrest somebody for reading the wrong sub, give it a few months.
Also, don't connect through Heathrow ever again.
Submission + - First full synthetic cell created in Minnesota (biotic.org) 2
AleRunner writes: The First fully synthetic cell has been created in the Department of Genetics at the University of Minnesota. Strictly it's described as a "cell-like system constructed entirely from known chemical components that can perform a complete cell cycle" and is able to replicate, but only for approximately five generations. The key advance is that the cell is "built entirely bottom-up from individually purified, non-living components" although the cell still contains material from an e-coli bacteria. "PURE is a defined mixture of 36 purified enzymes from E. coli bacteria" which includes ribosomes and provides the infrastructure for genetic replication. CNN has article on the advance including interview material with Professor Kate Adamala who lead the research and says “I know the full ingredient list of the cell, I know exactly what chemicals, what molecules at what concentrations,” she said. “It is fully defined, which means we can engineer it.”
Comment Re:Yes. This is how you keep housing costs down (Score 1) 126
What the fuck is a "net zero" HVAC?
A window. The top models come with a sunscreen.
Fuck that.
Living in New Orleans...with easily avg temps in the mid to high 90's with mid to high 90's % humidity too....AC is a necessity.
That's been long known here....can't fathom why EU is having such a problem simply using AC when needed.
This isn't rocket surgery , this isn't NEW.
Comment Re:Yes. This is how you keep housing costs down (Score 1) 126
Natural gas is common in many southern states....TN, AL, MS, LA, AR and TX.....I've lived and visited there most of my life and it is common.
I've only lived in one apartment ONCE didn't have gas and I will not do that again.....I prefer gas to cook on and is cheaper for heat and water heating than electric by far....
Comment Re:The Oligarchy Awakens (Score 3, Insightful) 126
Solar is already cheaper than coal
People and companies are STILL FREE to use all the solar they want, or any other source....
It just isn't mandated by the state.
Comment Re:Remind me again... (Score 0) 126
.. which major American political party claims it is in favor of local control?
I would posit this IS an example of local control.
Most things of this nature need to be handled at the state level.....not at the federal level.
