“Given how complicated things in nature are, you might think the programs running them would be very complicated,” he began.
This one quote points to the main problem I had with A New Kind of Science, which was that Wolfram seemed to start with a plausible, interesting premise -- "patterns we see in nature can be modeled using very simple cellular automata" -- but then he seemed to repeatedly conclude that "these cellular automata are therefore what are running the processes of nature," which seems absurd.
It's like he has this bizarre short circuit in his brain where he thinks a successful model is necessarily identical to the real process, so that if you stare deeper and deeper into the model -- which you yourself created -- then you will be able to understand more about the real-world process without ever doing so much as a real-world experiment. What do you call that, if not a god complex?
Otherwise, I found Wolfram's text to be more or less indistinguishable from any other long-winded crank science manifesto that purports to refute all of known science and usher in a new age of progress if only the bastards weren't trying to keep me quiet, god damn them! It seems a shame that he's dedicated so much of his life to such pursuits when he seems to be an otherwise competent mathematician and programmer. Kind of a wasted life, if you ask me.