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+ - Creating bacterial 'fight clubs' to discover new drugs->

Submitted by Science_afficionado
Science_afficionado writes: Vanderbilt chemists have shown that creating bacterial "fight clubs" is an effective way to discover natural biomolecules with the properties required for new drugs. They have demonstrated the method by using it to discover a new class of antibiotic with anti-cancer properties.
Link to Original Source

Comment: Re:Not surprised (Score 4, Insightful) 183 183

by Rei (#50015665) Attached to: Uber France Leaders Arrested For Running Illegal Taxi Company

Uber drivers are subsidized by everybody else. Taxi drivers have to pay high insurance rates because the act of driving a long distance every day for a ton of strangers is a job that inherently leads to a much higher statistical rate of payouts. If they're driving as a taxi on regular car insurance, it's you that's paying the bill for their swindle of the insurance system.

Comment: Re:No GPL (Score 3, Informative) 93 93

by caseih (#50015653) Attached to: Ask Slashdot: Choosing the Right Open Source License

You've been misinformed. I don't blame you, but you've apparently never read the GPL. It explicitly says:

You are not required to accept this License, since you have not signed it. However, nothing else grants you permission to modify or distribute the Program or its derivative works. These actions are prohibited by law if you do not accept this License. Therefore, by modifying or distributing the Program (or any work based on the Program), you indicate your acceptance of this License to do so, and all its terms and conditions for copying, distributing or modifying the Program or works based on it.

Thus you are free to download and use it for any purpose, provided you do not redistribute it or derive software from it. Pretty clear.

Perhaps you meant to say there's a lot of GPL software you'd like to incorporate into your own software but you can't because of the license. You would be correct. And you won't get any sympathy either. As they say, write your own code!

Comment: Re:Welcome to reality (Score 1) 148 148

by caseih (#50015547) Attached to: SCOTUS Denies Google's Request To Appeal Oracle API Case

How do you figure? You say there have been
dozens of lawsuits. Please name a few. Because I can't think of any. I can think of arguments over look and feel and those were thrown out. I also know the DMCA specifically allows interoperability.

NVidia's may be in gray territory morally, but legally they are completely safe (at least they were before this rubbish). Their closed-source binary blob in no way links or even refers to kernel APIs. Instead the shim layer (which is GPL and distributed as source only) compiles against the kernel and then links to the blob. This is completely legal because the actual tainting is done by the end user, not NVidia. So no, their binary drivers are not "begging for a lawsuit."

The owner of the API certainly doesn't get to determine fair use. For that matter a copyright holder doesn't have the right to define this in general. Nor do third parties. They can claim fair use, but ultimately it's decided in court, which is what Google will rightly be arguing for.

I'm no Google fan, but your claims certainly don't stand up to recent history, and they aren't reflected in the law as written and interpreted up until now.

Comment: Re:What plan? (Score 1) 84 84

How do you come to that assumption?

By linking to a peer-reviewed paper on the subject?

A nuclear warhead has lots of trouble to even "hit" an asteroid.

Essentially every space mission we have launched for the past several decades has had to navigate with a far more precision than that needed to get close to an asteroid and activate a single trigger event when close by.

Comment: Re:What plan? (Score 3, Interesting) 84 84

We send spacecraft on comparable missions all the time. And it doesn't really take a spectacularly large payload to destroy (yes, destroy) an asteroid a few hundred meters in diameter. 1/2-kilometer-wide Itokawa could be blown into tiny bits which would not recoalesce, via a 0,5-1,0 megatonne nuclear warhead, a typical size in modern nuclear arsenals (in addition, the little pieces would be pushed out of their current orbit).

I know it's a common misconception that "nuking" an asteroid would simply create a few large fragments that would hit Earth with even more devastation, but that's not backed by simulation data. And anyway, even if it didn't blow the asteroid to tiny bits (which simulations say it would) and even if it didn't push the remaining pieces off trajectory (which they say it does), anything that spreads an Earth impact out over a larger period of time is a good thing - it means the higher percentage of the energy that's absorbed high in the atmosphere rather than reaching the surface (less ejecta, lower ocean waves, a broader (weaker) distribution of the heat pulse, etc), the weaker the shockwaves, the weaker the total heat at any given point in time, and the more time for Earth to radiate away any imparted energy or precipitate out any ejecta cloud. If the choice is between 15 Chelyabink-sized impactor (most of which will strike places where they won't even be witnessed) or one Meteor Crater-sized impactor (same total mass), pick the Chelyabinsk ones. 50 10-megatonne meteor crater impactors or one 500-megatonne Upheaval Dome impactor? Pick the former. The asteroid impacts calculator shows the former generating a negligible fireball and 270mph wind burst at 2km distance, while the latter creates the same winds 25km away (156 times the area) and a fireball that even 25km away is 50 times brighter than the sun, hot enough to instantly set most materials on fire.

But that's all irrelevant because, quite simply, simulations show that nuclear weapons do work against asteroids.

What we need is enough detection lead time to be able to launch a nuclear strike a few months before the impact date (to give time for the debris to disperse). There is no need to "land" or "drill" for the warhead. There is no pressure wave; instead, an immense burst of X-rays is absorbed through the outer skin of the asteroid on the side of the explosion, causing it to vaporize (unevenly) from within, especially near the ground zero point, and creating powerful shockwaves throughout its body. In addition to ripping it apart, the vaporized material and higher energy ejecta flies off, predominantly on the side where the explosion was detonated, acting a broad planar thruster.

Comment: Re:It never worked properly anyway... (Score 1) 135 135

by caseih (#50010817) Attached to: Chromecast Update Bringing Grief For Many Users

I've never had any luck with any of these streaming stick devices. The only thing that works for me a a full-blown computer connected to HDMI.

Of course there are bugs there too. It took Gigabyte two years to release a EFI firmware that fixed the HDMI audio bug where after turning off the TV, HDMI audio would disappear until you rebooted.

Comment: Re:How is this news for nerds? (Score 1) 1052 1052

by cold fjord (#50009597) Attached to: Supreme Court Ruling Supports Same-Sex Marriage

It would be great if that were true, but it probably isn't in the long run. Children don't have to consent to lots of things that happen to them now. There are other societies that have or have had child brides, so there are obviously social mechanisms to enable that. With diversity and immigration policies brining in more and more people from those societies I wouldn't be surprised if they considerably outnumber the gay population now. That is before you even consider traditional pedophiles. Over time advocates for minor-adult sex will have more political power. Speaking of political power, I hear there is a former Speaker of the House paying millions in hush money over sex with a minor decades ago. Besides, there are 50 years of prep coming to enable it, academicians working on normalizing minor-adult sex now, just as there were people doing that for homosexuality decades ago. In some parts of society, such as Hollywood, powerful people are known as child abusers, and nothing is said. Fifty years ago homosexual marriage couldn't happen. Today child marriage "can't happen," but that isn't likely to remain true as things stand. Standards were destroyed to enable homosexual marriage, they won't magically reappear when needed to stop child marriages.

Comment: Re: Demographics (Score 3, Insightful) 248 248

by mi (#50008685) Attached to: FB Reveals Woeful Diversity Numbers

... yada-yada-yada .... Why do they [gangs -mi] form? That's pretty simple. When you're pushed out of the economy [...]

So, you've gotten past denying the higher likelihood of Blacks belonging to a gang, and are now listing excuses for it? Nice.

So, is it still "stereotype", if it is true? Is it "racist" to point out, that African Americans have darker skin?

All blacks are violent criminals in the minds of police.

You keep saying these things, but remain unable to explain, why these very same racist police do not treat Asians just as badly as they (supposedly) do Blacks. Anecdotes about Korean kids studying Math don't count. Koreans are but a fraction of Asians in America — there are vastly more Chinese, for example. There are great many Vietnamese. Then there are Indians and Pakistani, who — being brown and with funny accents — would've made a perfect target for racism.

And maybe they are a target — I do not know. But I do know, they don't burn pharmacies for some reason...

Police have a long history of treating people of different races and national origins differently.

Citations? Single anecdotes don't count — statistics, please... Cite me a study or two.

You'll find that we'll see a dramatic change in black and latino stereotypes

I asked this question up above already, but you — "cowards on race" — have all dodged it. Why is it, that even the most vile stereotypes of Jews — who were certainly mistreated in Europe for centuries — do not contain anything even remotely like smashing police cars or robbing storekeepers?

Comment: Re:200 cycles? (Score 3, Insightful) 122 122

by Rei (#50008581) Attached to: Samsung Nanotech Breakthrough Nearly Doubles Li-Ion Battery Capacity

On the other hand, if they're doubling capacity, then you only need half the number of cycles (it actually even works *better* than that, as li-ion cells prefer shallow charges and discharges rather than deep ones - but yes, fractional charge cycles do add up as fractional charge cycles, not whole cycles). If you have a 200km-range EV and you drive 20 kilometers a day, you're using 10% of a cycle per day. If you have a 400km-range EV and you drive 20 kilometers a day, you're using 5% of a cycle per day.

Comment: Re:well then (Score 5, Insightful) 122 122

by Rei (#50008563) Attached to: Samsung Nanotech Breakthrough Nearly Doubles Li-Ion Battery Capacity

Top commercial li-ion capacities are about 30% more than they were 5 years ago. And today's batteries include some of the "advances" you were reading about 5 years ago.

I'm sorry if technology doesn't move forward at the pace you want. But it does move forward when you're not looking. Remember the size of cell phone batteries back in the day?

The perversity of nature is nowhere better demonstrated by the fact that, when exposed to the same atmosphere, bread becomes hard while crackers become soft.