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Comment Re:Figures (Score 5, Insightful) 149

"There is no safety or cost reason to prefer this over normal analog protein vaccines. Only advantage MRNA has is reduced up front capex."

Nice attempt at shaping the discussion to flow down the limited paths you prefer. In reality world the gigantic advantages of having straightforward yearly influenza vaccines be mRNA-based is that (1) after enough experience it would become possible to reformulate the vaccine midseason if the dominant flu strain changes (2) if a 1918 Kansas Flu boils up out of a giant pig farm somewhere it will be possible to create an mRNA vaccine for it and get it into distribution rapidly.

Comment Multiple rug pulls (Score 5, Informative) 90

The streaming services have already done multiple rug pulls, rights-stripping acquisitions, and bankruptcies to take away "purchased" streaming rights and force people to pay a second time (and a third, and a fourth...). But yeah, the people who have CD players with analog outputs and who buy CDs are the dumb ones.

Comment Wrong assumption in the article (Score 5, Interesting) 83

I, Steve Wozniak, did not participate in the theft of the BASIC. It was funny to me to see others enjoying doing this. I had never used BASIC myself, at that time, only the more-scientific languages like Fortran, Algol, and PL-1, and several assembly languages. I sniffed the air and sensed that you needed BASIC to sell computers into homes, because of the book 101 Games in BASIC. I loved games and saw games as the key. It was the [MS] BASIC that inspired me to write a BASIC interpreter for my 6502 processor, in order to have a more useful computer.

Comment Wilhoit's Law (Score 5, Informative) 97

"Conservatism consists of exactly one proposition, to wit: There must be in-groups whom the law protects but does not bind, alongside out-groups whom the law binds but does not protect"

To conservatism I would add billionaireism.

[note that this is not Wilhoit the academic political philospher, but a different Wilhoit]

Comment 40% growth forever (Score 1) 39

The smartest guys in the room somehow failed to realize that 40% compounded growth forever at 80%-3000% gross margins wasn't possible. It can happen for 5-10 years of an economic turnover (whether driven by new technology, new forms of organization, immigration, or other fundamental changes) but just because it happens to some organizations for 5, 10, even 20 years does not mean it can/will happen to every organization - and trees don't grow to the sky.

Comment Re:Smells fishy to me (Score 2) 146

Before starting a local nuclear power industry Korea did a thorough study of the global industry and decided to basically copy US NRC regulations. They had the option to start from scratch and create a new regulatory framework but they decided to go with one that had experience behind it and known weak spots documented. I don't track that part of the industry closely any more but my understanding is that Korean nuclear operational and safety requirements are now tighter than those of the US.

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