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Comment: Lipid formulations of cancer drugs exist (Score 3, Informative) 39

by ponos (#49766721) Attached to: Machine That "Uncooks Eggs" Used To Improve Cancer Treatment

Lipid formulations of cancer drugs already exist, notably liposomal doxorubicin. Usually these result in better intracellular delivery and less toxicity. The problem is that making stable lipid formulations is quite hard and the resulting product quite expensive. If this, apparently simple, method can create liposomal carboplatin (or whatever other drug), it could allow cheaper and more diverse liposomal anti-cancer drugs. That would be nice. Especially carboplatiin (and cisplatin) are extremely important for many, many different chemotherapy protocols.

Comment: Re:"WSJ stunt to maximize anti-Clinton engagement" (Score 2) 231

by ATMAvatar (#49756149) Attached to: WSJ Crowdsources Investigation of Hillary Clinton Emails

Please explain how "reviewing Hillary Clinton's emails from her time in office" automatically constitutes "publishing pro-GOP progaganda"?

It's the "on Benghazi" part you omitted. You know, the tragedy where four people were killed, and Fox elevated it to 24/7 coverage, national crisis levels for multiple years trying to uncover a cover-up conspiracy that didn't exist.

Comment: Re:useful (Score 1) 173

Sure. Of course, you're going to prove that it was a management directive, and not just plain old IT incompetence or malice that led to "deleted" profiles being left around in the system, right?

If the IT guys are partly to blame, they should be lined up right alongside their managers for those whippings. And I'm pretty sure that you'll find more often than not that the IT guys are just as clueless and incompetent as their clueless and incompetent bosses.

Irrelevant.

Obviously, if it was a management directive, it's management's fault. However, if the lack of security is due to ignorance/incompetence on the part of IT, it's still management's fault, as it's their job to hire and/or train IT for security (and fire if necessary).

Internally, management is free to assign blame and take action against IT, be it through improvement plants, pink slips, or (in the case of malice) lawsuits. But make no mistake - management holds final responsibility - that's part of being in leadership.

Comment: Re:Not as easy to read as Python though (Score 1) 413

by TeknoHog (#49746655) Attached to: The Reason For Java's Staying Power: It's Easy To Read

Have you ever looked at the Fortran sections of CHARMM (MD package)? You want something hard to read that will make your head explode, go look at some of that mess! Not only is everything in CAPS there are space indents in the code and if you don't match those up, WHAMMO! error time!

I haven't had a look, but from your description I assume it's Fortran 77 (or even older, though that's unlikely). It's a good point, though; everything good I've said about Fortran refers to F90 or later. I agree that F77 is a mess and it lacks a lot of the modern niceties, for example with vector/matrix types (imagine writing auto-parallelized matrix math in the 1990s).

I'm pretty sure that all the bad things people generally say about Fortran are because they're only familiar with the horrible old versions. The change to F90 didn't exactly happen overnight with all the legacy code around; the only time I've worked with F77 was at CERN in 2001, but fortunately I got to write my part in F90, only using the legacy bits as reference for the data format.

Comment: Re:Not as easy to read as Python though (Score 2, Interesting) 413

by TeknoHog (#49742895) Attached to: The Reason For Java's Staying Power: It's Easy To Read

BTW, in case you haven't noticed, Python syntax is similar to Fortran syntax which is among the oldest, if not the oldest programming language still alive.

This. I think Fortran (and now Julia) strikes the best balance, because it doesn't have the tab/space issue that may produce problems, especially when sharing code. Like Python, it lacks the ugly {} ; punctuations, but it needs something to denote the end of a block, so it uses the English word "end" to keep things simple and clean.

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