When I first started to use Hugin about
... probably 6 years ago
... it was a very manual tool chain (unlike you, my experience is from using it with very little RTFM). I needed to dive back into it about 6 months ago to bolt together a square array of microscope images into a 5x5 array - for work, and where I needed to be able to explain exactly what had been done - and so why straight lines weren't straight. For that, for confidentiality reasons I had to do the work on the client's computer (windoze), not on my own machine Linux, and I had about 6 hours to deliver results in an IT milieu where installing anything takes a minimum of 2-3 days (and approval of new software dypically takes 3-4 months)
... well, lovely environment, but that's the rules I have to work through and around. I get paid for working microscopes, not doing IT arcana. I dived off to PortableApps.com and grabbed the Portablised Windows version, dropped it onto a USB drive, copied that to the secured machine, and got to work.
Is it drag'n'drop? No. Is it MUCH faster and easier than it used to be? Yes. Depending on your subject, the system will often automatically pick control points pairs between images (though you do need to make sure the images are correctly sequenced, particularly for 2d arrays). My photos, being almost abstract, of low contrast, and quite uniform colour really give the control point algorithm ("panostift", IIRC, I don't have bandwidth here to d/l it. Rebuilt laptop, toying with Tor) a hammering, but it still manages to get some points.
"Fully automatic" isn't a good phrase in my lexicon. It might be appropriate if you're taking city-scape panoramas, but I don't waste much time visiting cities unless I'm being paid. Microphotographs come up from time to time at work. Array panels of rock outcrops also need doing too - a few dozen images to document structural complexities.
Long story short - the system has improved a lot over the last few years. If you need to take detailed control of your photo stitching, then its certainly worth a look. I notice (from archaeology work last year, trying to produce 3-d models of archaeological artefacts) that there has been a lot of development in this whole area over the last half-decade or so. Definitely worth a shot.
Since the Hugin tool chain is all open source stuff, I'd be fairly astonished if the M$ people haven't been plundering it for ideas, if not code. Colour me cynical.
The PortableApps version is damned useful - it lives on my "get the fucking job done NOW" hard drive/ tool box. Only gets used every year or so, but when I need it, it's good.