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Comment Why is this the case? (Score 4, Insightful) 71

Is there something instrinsic about the functions that Adode Flash does that makes this inevitable or is it that Adobe started with an unfixable design model or is it that Adobe is incompetent. Offhand I don't see a fourth option. Well maybe just bad luck.

SO for example. In the first option, we can compare the functionality of adobe to other systems. Silver light or H264 is not the same thing since unless I'm mistaken Adobe flash is not just a codec but also a language. So a better point of comparison is Java. If it's a matter of functionality leading to intrinsic vulnerabilities in a browser setting then one would expect Java and Flash to have the same frequency of exploits. Perhaps what saves Java is that it's usually off by default and asks permission to run.

Alternatively if it's an unfixable design model, I don't see a dimes worth of difference between this an incompetence except that the former is worse because one knows the design was incompetent but persists in selling it. It's like the difference between premeditated murder and manslaughter..

So given they could eliminate most expoits why don't all browsers quarantine Adobe or classify it as suspect malware.

Comment This will be short lived (Score 0) 359

While Democrats and Republicans abuse 501C3 laws to obfuscate political contributions it's patently true that Republicans do to great excess. Evidently it's simply embarrassing to own a coal mine and fund people who deny climate change. One might quibble about degrees here but that's my impression.

Thus the push back on the IRS when they called BS on this and discovered they were going after more repupublican than democratic orgs. A political no no even if pure logic dictates thats the distribution of abuse.

Here the same thing is going to happen. Even the maldovian spam artists discovered there was no profit in fake news about hilary but tonnes of gullible people on the trump side of things willing to click.

money talks. The experiment has been done. Sorry if the results embarrass your politics.

Comment No it means more and less than that (Score 4, Informative) 90

Well not exactly.
The discovery of an antibody that targets a non-variable site is important in several ways. I'm not sure how good a therapeutic drug it will make. Antibodies are huge and hard to make so depending on the dose required it could be prohibitive to inject enough of the stuff in an active form to do any good. Massive proteins often are lousy drugs. THat's not to say that antibodies can't be used as drugs. There's a lot that are on the market now, for example Humira. But that's going after receptors in the host not viruses so it's a different regime.

But what is good about this is three things. You learn where you can bind on the virus, you learn the binding mode of the contact points, and finally you learn that that binding mode is protective across most HIV. It's not uncommon to have something that binds HIV well but fails to be protective. Given this structural knowledge one can now try to design either small molecules or other smaller proteins than an anti-body that bind in a similar manner and target either the same binding site or the same origins of protection.

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