As bad as 2FA over SMS is, that doesn't stop it from being widely used. I can see a lot of messages ending up there.

This is step 1 in trying to sell their flailing business. They obviously don't expect any more growth or they'd stick with running their own servers. Buyers want to know they can carve up the company easily, so migrating to a public cloud gives them some assurances this is possible. They're certainly hoping to get scooped up on their disintegrating brand awareness before there's no value left.

Appendix 1 (pp 65–75) provides a summary of each study. In 34 (67%) of 51 studies, the minimum age of participants was 55, 60, or 65 years. The maximum reported age of a participant was 115 years and the minimum reported was 37 years, although not all studies recorded minimum and maximum age. For studies that recorded information on the distribution of sex, the proportion of female participants was between 43% and 72%. Three studies were exclusively in female participants6,64,67 and one study was exclusively in male participants.29 Reported follow-up periods ranged from 3 to 23 years, although many studies reported follow-up either as a median or mean. 20 (39%) studies were done in Europe, 17 (33%) in North America, 12 (24%) in Asia, and two (4%) in Oceania (both in Australia). Several studies reported on different dementia subtypes. 43 (84%) studies reported on dementia (including one study on non-Alzheimer’s dementia55), 24 (47%) on Alzheimer’s disease, 16 (31%) on vascular dementia, one (2%) on frontotemporal dementia, and one (2%) on mixed vascular dementia and Alzheimer’s disease. The studies reported on one or more pollutant exposures, with 40 (78%) reporting on PM25, 28 (55%) on NO2, 17 (33%) on PM10, 12 (24%) on NOx, ten (20%) on black carbon (BC)/PM25 absorbance, ten (20%) on annual O3 (O3 was reported on as warm-season or annual exposure, with two [4%] studies reporting on warm-season O3), six (12%) on PM25–10, five (10%) on carbon monoxide, five (10%) on sulphur dioxide, and three (6%) on nitrogen oxide. Additional pollutants were reported in two or fewer studies. 48 (94%) studies were cohort studies, two (4%) were cohort studies with a nested case–control analysis, and one (2%) was a case–control study.

Study-level risk of bias and confidence in the overall body of evidence were assessed with the Office of Health Assessment and Translation tool, and publication bias was examined.