titanium dioxide is nano particles. get them into the body. pollute it. long ago i decided that the empirical evidence was thus: the goal apparently of large corporations is to kill as many people as possible, as slowly as possible, and do so in a way that nobody's hands ever appear dirty. i wouldn't take back what i know now for anything, but it's been a long long hard road. (over 30 years of observation, changing diet, cause, effect, discussion, research, biomedical papers, books, old books, medical journals, fringe sites, etc).
(science viewpoint: it helps the stuff get in further and deeper and more completely and because less is excreted as metabolites, it must be working better, see?!) only problem is they cross organ membranes they're so small, the agglomerate in places they should never be in the first place, and lastly and most importantly the body doesn't know how to get them out.
EDTA chelation, however does get it out.
or to a lesser degree so does eating food that naturally chelates, like cilantro.