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Comment Re: Get off of VMWARE ASAP, but be warned (Score 1) 56

We moved off on-prem VmWare to Azure cloud. VmWare had a workload management function called VmMotion - to automatically pauses and move VMs between hardware blades, supposedly without skipping a beat. But VMotion used to break cluster management software we ran. So our admins turned it off for susceptible VMs - those stayed 'sticky' on the blade they spun up on.

  As we moved to Azure, I asked how we could avoid a similar situation. Turns out Azure has a similar 'feature' called 'Live Migration'. The difference is you cannot turn off 'Live Migration'. Microsoft uses it when it wants to. Thankfully, our cluster management software was fixed/desensitized by the time we moved to Azure.

Despite that, I think the on-prem VmWare was at least a couple times more stable than Azure.

Comment Re: Papers (Score 1) 37

There are numerous interventions that have been shown to do just that, even non-invasively. GPL-1 agonists and psilocybin are two examples. The opposite can happen as well: sudden addictions in frontotemporal dementia, for example. Addiction is a well-understood mechanism modulated by the nucleus accumbens, which is what they targeted. An analogy is treatments for Parkinson's disease or essential tremor: you walk in with a tremor, right after the procedure you have no tremor. You're right that physical withdrawal will happen, and it's very uncomfortable, but that will go away after a few days, or it can be softened with methadone.

Comment Re:I don't trust Dr's claim re treating alzheimers (Score 1) 37

You're correct about late-stage Alzheimer's disease (AD), where there is widespread cortical and hippocampal degeneration - those areas are not coming back. However, early-stage AD can still benefit from these therapies.

Parkinson's disease (PD), though, is actually the first disease deep-brain stimulation was developed for, in the 80s. That's because PD is a degenerative disease of only a specific brain region (the substantia nigra pars compacta) and the downstream effects are a network dysfunction. Motor symptoms are treated with exactly these kinds of therapies - deep brain stimulation (DBS) of the subthalamic nucleus and globus pallidus internus, as well as high-intensity focused ultrasound (HiFu) ablation of those same areas. Same for essential tremor and dystonia (different targets). None of those therapies treat non-motor symptoms, and they don't even treat all symptoms of PD equally, but they are very effective.

DBS for OCD has been FDA-approved for over a decade now, and there are many trials going on for DBS of almost every psychiatric disorder you can think of, starting with the biggies, major depressive disorder and generalized anxiety disorder. Many of those target the nucleus accumbens, like this therapy.

This technology (MRgLIFU) is less than a decade old and is being tried for all of the indications that DBS and HiFu have been used for, but so far it's all trials, none of the therapies have reached FDA-approval stage. It's a very promising technology, it's very real and very much applies to movement disorders like PD as well as psychiatric conditions, and even early-stage AD. However you're right that we're probably not bringing back the memories of people with late-stage AD.

Comment "I want to know what war is! I want you to show me (Score 1) 155

"I want to know what war is! I want you to show me!!" (Apologies to 'Foreigner')

No, Europe is not at war with Russia - not yet. Sure, Europe spies, facilitates killing of Russians in Ukraine and Russia, and holds onto Russian money. On the other hand, Russia kills Russian dissidents in Europe, snips cables, holds onto European assets and occasionally jams GPS. This isn't war. The two sides should be actively negotiating a wind-down of hostilities with each other and in Ukraine, and retaliating proportionally to offenses to keep each others worse instincts in check. But this is not war.

Comment Re: False optimism - no permanent tech advantages (Score 1) 321

This is not the Jetsons. If Ukraine had a robo-army, by now there would be no "busification". And yes, Russia is losing more men, but why do you think that is? It is because the Russians are attacking, breaking cover. If the Ukrainians attacked, the same would happen to them.

It may be that the Ukrainians have superiority in autonomous targeting drones; that the Andurils and tech startups of the West help them in this. But how long do you think this superiority will last? Will this period be long enough to enable the Ukrainians to break out and get the the Donbas back? What do you think will happen to the casualty exchange rate when Ukraine attacks?

Yes, drones can help attack, but they cannot hold land. That requires men. Again, we are not in the Jetsons era yet.

Look, Ukraine is already in a demographic death spiral. Using EU funds, it is importing guest workers, already reluctant to enter a warzone, while shipping of it's own youth to die at the front. Ukraine is desperate to involve the West more deeply in the war. This is unsustainable and dangerous for both itself and the West.

Say, your plucky smaller friend is getting trashed in a bar fight with a big guy. He is gesturing at you frantically to join in. Won't the wise option -- for him and for you -- be to urge him to stop the fighting and try to come to terms with his opponent? Rather, the West keeps slipping Zelensky the equivalent of knuckle dusters, tells him "Keep going", "punch him over there", "look out for his left hook", and swears at the Russians while quietly buying uranium and gas from them. Rocky Balboa's coach is doing business with Ivan Draga.

Those Ukrainian defensive lines you speak of, the ones that are too sacrosanct, they are no guarantee. The Ukrainians need to scramble and build new ones behind them anyway. The Russians are still advancing, imposing losses on Ukraine's assault brigades that have taken back territory in the last two months. The Ukrainians aren't going to get a dramatic infusion of soldiers. So they need new lines far in the back anyway, either as defenses after surrendering territory, or as fallbacks if the frontline is breached. The West should help Ukraine build new lines in the back (the only real security guarantee), encourage them to make concessions for peace and broach the topic with the Russians

Comment False optimism - no permanent tech advantages (Score 2, Insightful) 321

There is no permanent tech advantage to either side in this war. Only the potential for peace is permanent

Ukraine used Turkish Bayraktars, Russians got Iranian Shaheds
Russians invented cope cages, Ukrainians got them too.
Ukrainians got FPV drones, Russians got them too
Russians invented fiber-optic drones, Ukrainians got them too.
Now if the Ukrainians get assault robotic and evac robots, the Russians will get them too

One side has most of Europe backing it; the other side has most of Asia. Too many resources behind both parties for either to lose easily.

Stop the fighting. There are no winners here. Only worse-off losers.

Both Russian casualties and Ukrainian casualties have long passed the 'unsustainable' mark. Now both side are getting close to the point where either side can tap out. But Ukraine is closer to that point than Russia. Yes, Russia is losing, but Ukraine is losing harder and faster - it has less land, men, money, and munitions than Russia. It is getting attrited faster. Ukraine has the bigger job ahead of it after the war - blowing up unexploded ordanance, demining, rebuilding, repopulating.

Ukraine needs to:
(a) make an offer that the Russians can at least use as a fig leaf to concede peace.
(b) Ukraine also has a problem with a section of insubordinate rightwing soldiery that resists any peace concessions. Ship them straight to the fight. Want to disobey? Go fight then! Just don't take the rest of the country with you.

Why? So Ukrainian people can live. So its current leader can live. So the country is not at risk.

Comment Re:Could get a lot messier for Iran (Score 2) 480

What planet are you on where people care more about the Internet than oil? The planet of your mom's basement?

In case you haven't noticed, Iran has already cut off its citizens from the Internet. Threatening to cut them off is like threatening to cut off cruise ships from Iowa.

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