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Comment It's not the ALPR. It's the registration lookup. (Score 4, Interesting) 64

It's not the ALPR. It's the registration lookup that's the problem. ALPR - the core tech - is genuinely useful. Consider this thought experiment: normal people (you, me and our neighbourhood posse) implement our own ALPR network. We run it on poles in frontyards, on old mobiles duct-taped to windows, on personal phones in its cradle as we drive around. We run torrents that sync ALPR data with trusted nodes. Someone vibe-codes an app that correlates ALPR data with public crime report: It flag plates possibly associated with crime, such as the casing of an area before burglaries. Another app detects bad driving (yes, where someone's "bad" could be someone else's "snazz").
So far, all is functioning as it should. Capturing ALPR data privately is just photography in a public area with no privacy violation. The plates are both and provide anonymity to vehicle owners, divers and passenger. The private ALPR network could help report concerns about specific plates to the police with no idea who owns the plates.

What breaks privacy is running a plate/car registration. Now you know the owner, where they live, whether they have insurance. Doing *that* should require lawful exigency or a warrant.

Comment Optimisation. (Score 1) 160

GM says its software business keeps roughly 70 cents of every dollar it brings in. That's a rare level of profitability in the auto industry, as many car sales generate just four to 10 cents per sales dollar...

Is GM exiting hardware and switching to software vehicles?

Will their upcoming model compete with Grand Theft Auto?

Comment Re: Get off of VMWARE ASAP, but be warned (Score 1) 56

We moved off on-prem VmWare to Azure cloud. VmWare had a workload management function called VmMotion - to automatically pauses and move VMs between hardware blades, supposedly without skipping a beat. But VMotion used to break cluster management software we ran. So our admins turned it off for susceptible VMs - those stayed 'sticky' on the blade they spun up on.

  As we moved to Azure, I asked how we could avoid a similar situation. Turns out Azure has a similar 'feature' called 'Live Migration'. The difference is you cannot turn off 'Live Migration'. Microsoft uses it when it wants to. Thankfully, our cluster management software was fixed/desensitized by the time we moved to Azure.

Despite that, I think the on-prem VmWare was at least a couple times more stable than Azure.

Comment Re: Papers (Score 1) 37

There are numerous interventions that have been shown to do just that, even non-invasively. GPL-1 agonists and psilocybin are two examples. The opposite can happen as well: sudden addictions in frontotemporal dementia, for example. Addiction is a well-understood mechanism modulated by the nucleus accumbens, which is what they targeted. An analogy is treatments for Parkinson's disease or essential tremor: you walk in with a tremor, right after the procedure you have no tremor. You're right that physical withdrawal will happen, and it's very uncomfortable, but that will go away after a few days, or it can be softened with methadone.

Comment Re:I don't trust Dr's claim re treating alzheimers (Score 1) 37

You're correct about late-stage Alzheimer's disease (AD), where there is widespread cortical and hippocampal degeneration - those areas are not coming back. However, early-stage AD can still benefit from these therapies.

Parkinson's disease (PD), though, is actually the first disease deep-brain stimulation was developed for, in the 80s. That's because PD is a degenerative disease of only a specific brain region (the substantia nigra pars compacta) and the downstream effects are a network dysfunction. Motor symptoms are treated with exactly these kinds of therapies - deep brain stimulation (DBS) of the subthalamic nucleus and globus pallidus internus, as well as high-intensity focused ultrasound (HiFu) ablation of those same areas. Same for essential tremor and dystonia (different targets). None of those therapies treat non-motor symptoms, and they don't even treat all symptoms of PD equally, but they are very effective.

DBS for OCD has been FDA-approved for over a decade now, and there are many trials going on for DBS of almost every psychiatric disorder you can think of, starting with the biggies, major depressive disorder and generalized anxiety disorder. Many of those target the nucleus accumbens, like this therapy.

This technology (MRgLIFU) is less than a decade old and is being tried for all of the indications that DBS and HiFu have been used for, but so far it's all trials, none of the therapies have reached FDA-approval stage. It's a very promising technology, it's very real and very much applies to movement disorders like PD as well as psychiatric conditions, and even early-stage AD. However you're right that we're probably not bringing back the memories of people with late-stage AD.

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