The Phase III study "Study 801" of the compound under discussion did have an open-label run-in period, *and* was placebo controlled.
I believe the ct.gov link below is the study under consideration. Regardless, the press release mentions the placebo control.
From the last link:
Zohydro ER was studied in over 1,100 people living with chronic pain who participated in the pivotal Phase 3 efficacy study or an open-label Phase 3 long-term safety study. The efficacy study that enrolled over 500 subjects with chronic low back pain met the primary endpoint in demonstrating that treatment with Zohydro ER resulted in significantly improved chronic pain relief compared to placebo.
Why does youtube need ssl?
I could understand logging in needs to be secure, but every page afterwards? They're public pages man!
Just sort of happened *shrug*
Interviewer: Now tell me, what exactly are you doing?
Spotter: Er well, I'm camel spotting. I'm spotting to see if there are any camels that I can spot, and put them down in my camel spotting book.
Interviewer: Good. And how many camels have you spotted so far?
Spotter: Oh, well so far Peter, up to the present moment, I've spotted nearly, ooh, nearly one.
Interviewer: Nearly one?
Cisco does own it. You are wrong.
UHF! Only saw it once, probably 15-20 years ago, and still remember that line...
I can highly recommend Ben's book "Bad Science". I bought a copy for each of my family members for the holidays. It gives a very realistic overview of the current state of medical research, both from the "mainstream" and "alternative" medicine worlds.
We don't know one millionth of one percent about anything.