The concept of custom mRNA vaccines was reported in the December 2025 issue of Scientific American magazine. There, such a vaccine was described as successfully treating pancreatic cancer.

To me the hoops that smoothbrains will jump through to avoid IPv6 and stay on legacy IPv4, especially when hosting, is pathetic. NAT, port forwarding, tunnels, blah blah blah blah.

I have something like ~1.2 trillion times the number of routable addresses that the entire IPv4 space has. Not all are reachable, of course, just the services that need incoming access and they're each on their own isolated DMZ.

Forgot to add: if you enable IPv6, be sure to use the browser extension IPvFoo. It shows a small 4 or 6 in your URI bar to let you know what protocol you're connecting to. Once enabled, you'll see just how much stuff out there actually is IPv6.

Started the move about 18 months ago when I decided to get off my lazy ass. My ISP gives out a /56 prefix, so that lets me run 256 /64 subnets/VLANs in the house, currently there are ~10 in use. Everything get a GUA through SLAAC and I use RAs (Router Advertisements) to give ULAs to everything. Any external facing services get their own VLAN and /64 for the system(s) as needed. Firewall blocks all incoming as they usually do by default and I punch a hole for the external-facing systems. They can't reach back into the network, they only answer the phone. All the systems update DNS dynamically if the prefix or full address ever change.

I have an SSH bastion set up. In all this time there has not been a single SSH attempt from the internet. On IPv4 it was constant background noice.
For those legacy IPv4-only systems on the internet, I set up NAT64. I have an IoT VLAN and IoT 2.4 GHz wireless network that are only IPv4 because a lot of IoT network stacks are junk.

I'm still farting around with it, but man oh man, there's no way I'd go back to IPv4. It was one of the best moves I've done in ages.

Trump objects to Anthropic's rules against autonomous use of AI in military operations. The real reason is that Trump wants systems of military offense that can operate without any person being held accountable for unnecessary civilian casualties.

Trump also objects Anthropic's rules against the use of AI for domestic surveillance. He wants to create the world described in the novel "1984".

I'm not seeing a paywall on the site. uBlock Origin must be doing something.

The UHF app on our Apple TVs & iOS devices and the UHF Server in Docker to act as a PVR gives us everything for a few $ a month paid in crypto.
We haven't had cable since ~1999-2000. Downloading and the *arrs have kept us happy, but the better half wanted to check out some live sports. So IPTV it was.

One of our guys said something to the effect of "Copilot is Corporate Chat. It knows all the useless filler of management-speak, but lacks the competence of the people in the trenches.

Ouch.

I've used Claude at home for ages. Work was wanting to get some AI stuff for us and the only 'blessed' one is CoPilot. Everything else it blocked. All senior management seems to know about AI is "Hurrr... Copilot and ChatGPT."

Out team of ~8 (pentestesting & VA) were unanimous about Copilot being crap and Claude being the top dog. So some higher ups OK'd a Claude Teams package for work. To bypass the CorpSec tards, we use it from our lab environment that has its own unmonitored link and IP range.

Anthropic/Claude is just so far ahead of OpenAI/ChatGPT and MS/Copilot it's not funny.

I wish my water was as cheap as $1,300 a year. My water bills added to $3,678.97 in 2025. In part, that was to pay for the replacement of a 50-year-old above ground water tank with an underground tank. Also, that paid for the ever-rising cost of electricity to pump the water from northern California to southern California. My water bill exceeded the sum of my electricity, natural gas, and phone bills. Note, however, that our water is among the best in the U.S.

Also in 2025, my sewer fees totaled $1,381.32. The sewage plant thourghly processes its input and then releases the result into a nearby natural creek. The area is an undeveloped watershed that is home to wild animals. Lawsuits against the sewage plant now require that the flow in the stream below the plant must be cleaner than the flow above it despite the fact that excrement from the animals washes into the stream. I am paying for the extra processing of the sewage.

I was already over 80 when I bought my Nissan Leaf EV.

The only time I needed roadside repair was when I misjudged a driveway and hit a curb at speed; that destroyed a tire. The Leaf does not come with a spare tire or even with space for one. So I needed a tow.

I recently had a minor collision. The paint was scraped on the left front. That part of the body shifted about 1/2 inch or less, causing a "click" when I opened the driver's door. All that was repaired in less than a week.

My wife (also over 80) regularly goes to a clinic for treatment. As we are now a one-car family, she uses door-to-door transportation provided by our local city. While waiting for a ride home, she has seen EVs towed from the clinic's parking lot. In every case, the owners of those EVs failed to charge their main batteries. Stupidity and negligence by owners are not reasons to denigrate the reliability of EVs. As I write this, my Leaf is plugged into a charger in my home's garage.

CVS drug stores sell two CVS-branded ointments that fight fungus. One is for athlete's foot, and the other is for jock itch. A tube of the jock itch ointment costs $2 more than a tube of the athlete's foot ointment. A close examination of the tubes reveals that they contain the same amounts of the same strength of the same product. They both have instructions for both kinds of fungus. Other than the names and the prices, they are the same.

re: ""where they will investigate why the barren red planet began to lose its atmosphere billions of years ago."

Isn't this already settled... for decades? Mars lost its magnetic field back then due to core cooling. We know this because of crustal magnetic signatures which were confirmed by MGS.

Once the magnetic field was gone, solar wind atmospheric stripping was unimpeded. This was confirmed by MAVEN in 2015.

Hopefully there are more relevant "science objectives" than this dead issue.

After a 41-year career in computer software -- first as a programmer but 30+ years as a software test engineer -- I am very glad I retired 22 years ago. News items like this destroy any thoughts I might have about going back to work.

I ran a dedupe on my drive and eliminated 8 redundant copies of the goatse guy.

#SaveWaterWithGoatse