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Medicine

Non-Invasive Stimulation of the Brain Ended Opioid Addiction, Cigarette Craving (jpost.com) 37

The Jerusalem Post reports that doctors at Haifa's Rambam Health Care Campus "have successfully treated their first Israeli opioid addiction patient using an experimental noninvasive brain technology, easing him through withdrawal in just 20 minutes..." [T]he team of specialists at the Haifa medical center intervened in the electrical activity of an area of the patient's brain called the nucleus accumbens, the core of the brain system responsible for feelings of satisfaction, pleasure, and reward. The treatment, based on technology from the Israeli company Insightec, is similar to the one used to treat symptoms of essential tremor and Parkinsonian tremor, under MRI control. In this case, the treatment was carried out with the help of a new technology that performs noninvasive neuromodulation, without heating or burning tissue, and allows stimulation in the same area of the brain to increase or suppress activity...

"Tests carried out a week later produced negative results for opioids and other substances," [said Dr. Lior Lev-Tov, director of the functional neurosurgery unit in Rambam's neurosurgery division and the one leading the new study at the medical center.] "The patient himself reported a craving score of zero out of 10 for using the drug, and even another side effect, a drastic drop in the desire for cigarettes, from three packs a day to just a few cigarettes, and with no urge to use alcohol. In other words, in a treatment that lasted about 20 minutes net, our patient was completely freed from an extreme dependence that had accompanied him every day for years. This is nothing less than a medical and therapeutic revolution."

Dr. Lev-Tov added that "This experience opens doors for us to treat a wide range of very serious illnesses such as PTSD, OCD, eating disorders, other addictions, severe depression, severe pain disorders, and I hope we will also be able to reach cognitive areas and treat attention deficit disorders, Alzheimer's, Parkinson's, and more."

Thanks to Slashdot reader Bruce66423 for sharing the article.

Comment Re:This. (Score 1) 86

I had one breakthrough DMT experience where I saw 'the machine elves' (I just saw what I describe as fast-moving fractals that I 'felt' were beckoning to me); but, we have matching experiences w/the other primary psychedelics: I only had relatively minor on-top visual distortions with even the largest doses of LSD (1500+ mcg) or mushrooms.

That said, everyone is different. I know that some of my friends absolutely lost their fucking minds on a few tabs of LSD and, purportedly, experienced wild hallucinations that I have to trust were real to them but haven't ever experienced myself.

Space

Blue Origin Rocket Exploded Thursday Night During Hot-Fire Test (cbsnews.com) 73

Spaceflight Now shared their video of the explosion, which the Orlando Sentinel describes as showing Blue Origin's rocket "become engulfed in flames. The fireball expands out and covers the entire launch pad as the fuselage of the rocket can be seen crumbling into the flames."

Blue Origin founder Jeff Bezos said on X.com "It's too early to know the root cause but we're already working to find it. Very rough day, but we'll rebuild whatever needs rebuilding and get back to flying. It's worth it." (SpaceX founder Elon Musk posted "Sorry to see this, I hope you recover quickly.")

It's unclear how this will impact future launches. "The rocket was destroyed," reports CBS News, "and as the smoke cleared, there was no sign of the erector-gantry used to move the New Glenn from its hangar to the pad and to raise it from horizontal to vertical. Likewise, one of two tall lightning towers was no longer visible." It was the first such on-pad explosion at the Cape since a SpaceX Falcon 9 rocket blew up on nearby pad 40 on Sept. 1, 2016... Blue Origin only has one New Glenn pad, the one that was damaged in the Thursday test. The New Glenn, which has launched three times, is a heavy lift rocket designed to compete head-to-head with SpaceX Falcon 9 and Falcon Heavy rockets. During New Glenn's most recent flight in April, an upper stage malfunction prevented a commercial internet satellite from reaching its planned orbit...

The New Glenn destroyed Thursday was to send 48 Leo internet satellites owned by Amazon into space [which were not on board for the hot-fire test]

Blue Origin posted on X.com that "Debris from our recent hotfire anomaly may wash ashore in the coming days/weeks. If you encounter any debris, do not touch or approach it for your safety."

"Spaceflight is unforgiving, and developing new heavy-lift launch capability is extraordinarily difficult..." NASA Administrator Jared Isaacman posted on X.com. "âWe will provide information on any impacts to the Artemis and Moon Base programs as it becomes available."

Thanks to long-time Slashdot reader symbolset for sharing the news.

Comment Re:How about? (Score 3) 95

I bought a used 2020 XC90 from CarMax last week. I did everything online from shipping it from Texas to Minnesota to financing the extended warranty. I walked in the door, gave them a cashier's check, and drove away within 10 minutes.

That's how it should be.

Comment Paywall free link (Score 5, Informative) 151

https://archive.is/uyPhk

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Anthropic is prepared to loosen its current terms of use, but wants to ensure its tools aren't used to spy on Americans en masse, or to develop weapons that fire with no human involvement.

The Pentagon claims that's unduly restrictive, and that there are all sorts of gray areas that would make it unworkable to operate on such terms. Pentagon officials are insisting in negotiations with Anthropic and three other big AI labs â" OpenAI, Google and xAI â" that the military be able to use their tools for "all lawful purposes."

Science

Scientists Found a Way To Cool Quantum Computers Using Noise (sciencedaily.com) 7

Slashdot reader alternative_right writes: Quantum computers need extreme cold to work, but the very systems that keep them cold also create noise that can destroy fragile quantum information. Scientists in Sweden have now flipped that problem on its head by building a tiny quantum refrigerator that actually uses noise to drive cooling instead of fighting it. By carefully steering heat at unimaginably small scales, the device can act as a refrigerator, heat engine, or energy amplifier inside quantum circuits.

Comment Re:I laughed (Score 1) 56

For Aldi, which uses Instacart, I assumed it was because there is no 'fee' for pickup, but they have to pay someone to shop for you. I consider the difference a convenience fee.

That said, by not shopping in store, I end up getting only what is on my list and end up paying FAR LESS than I would if I was wandering around.

Comment Re:Linus is right, but this is really not news (Score 1) 82

NT also virtualized the DOS environment (ntvdm) where 9x didn't and that is a very important distinction. In th 9x days, games and even drivers were executed in the DOS environment. As soon as you would open command.com, it was a ticking timebomb for when a blue screen would happen. If you could avoid DOS and 16bit memory shimmed binaries, 9x wasn't nearly as fragile as everyone generally dealt with

Comment Re:Does this mean it'll stop sucking? (Score 1) 27

I found GP2.5 to be great at academic-style research and writing; it was absolutely awful at writing code. So; I would tell it to plan some thing for me and write it in a way that could be used by another agent (Claude Code) to build the code to do the thing. In this way, it has been great! I haven't yet attempted it with 3.

That said, I found GP3.0's page to be hilarious:

It demonstrates PhD-level reasoning with top scores on Humanityâ(TM)s Last Exam (37.5% without the usage of any tools) and GPQA Diamond (91.9%). It also sets a new standard for frontier models in mathematics, achieving a new state-of-the-art of 23.4% on MathArena Apex.

It then proceeds to show, lower down on the page, an example of what it can do, by showing off 'Our Family Recipes". If there's anything that touts PhD-level reasoning and writing, it's a recipe book.

Comment Re:The problem with SAS (Score 1) 27

SAS has been dead for 15y; it started with R and then Python absolutely destroyed it. No one teaches SAS in universities any longer, why would they? It's terribly expensive and absolutely fucking dead.

We migrated away from SAS back in 2017 and never looked back. The only verticals still using it are heavily regulated and running long-standing legacy code that they're slowly migrating to Python.

I remember absolutely dying when they tried to renegotiate our contract UP back in 2015. I flat out told them they were dead and we were moving away from them and they told me, "good luck managing your data without us!"

Two companies and 10 years later, we're doing just fine and they are not.

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