Comment Re:We don't know what to do with AI (Score 1) 11
But whatever you do don't use it to make clean room implementations of Office!
Dude.. how fucking funny would it be if someone actually showed up to the competition and presented EXACTLY that.
Comment Re:We don't know what to do with AI (Score 1) 11
...please help us figure it out. We welcome all suggestions. Please. Anything.
If you aren't going to use to make weird porn then why did you even bother building it?
Comment Sounds like mil-tech bullshit (Score 1) 33
None of the specifications seem to be useful for the advancement of science. Honestly, this seems more like a Skunk Works project.
Comment I got this for you ; (Score 1) 711
News for nerds: No; Stuff that matters: Yes
You unfortunately have found yourself on the short end of the English version of a most vexing parse.
Comment Re:Good. (Score 1) 47
If you try to find the flaws as a defender, you have already lost.
Non-sense! There are plenty of very well designed software packages built using defensive programming practices that still have security flaws. To claim you have already lost when using those measures is to claim that only code with years of tireless review like NASA's near flawless software is good enough.
Comment Good. (Score 4, Insightful) 47
Just because we lacked the resources to find software flaws didn't mean that there were never massive vulnerabilities just waiting to be discovered, it just means it required dedication to find them. The lack of investment in security is about to be laid bare for all to see. Those that are actually interested in making secure software now have the opportunity to get even closer to that goal. Everyone that has been doing (and continues to do) the bare minimum is about to get a lesson in the importance of investing in real security.
Good security is expensive but having bad security is about to cost a whole lot more.
Comment The problem is businesses. (Score 1) 153
The issue of daylight savings has largely been solved by shifting clocks a minute every day for sixty days. The obvious problem is that we didn't build our electronics based on the concept of variable lengths in the days. However, we could mandate that all new electronics either have a built-in calendar, have NTP capability, use celluar towers for synchronization, or not have a clock at all and at the end of a decade or two we could switch to a much healthier approach. However, it will never happen because of businesses like trains, airlines, financial markets, and international logistics rely on a synchronized timeline which means it would need to more than just a single nation that uses this scheme but the whole world.
TL;DR: it's just not lethal enough of a problem to get solved, especially when the money changers get involved.
Submission + - SGI IRIX Indigo Magic Desktop recreation with AI: Cyanotype Blueprint Desktop (niten.irix.expert)
MIPSPro writes: Someone has re-created the Indigo Magic Desktop for the SGI IRIX operating system as a rather large scale undertaking with dozens of applications and preferences straight out of 2006. It's a BSD licensed affair with an actual IRIX port and several other platforms including Solaris SPARC and x86_64 BSD and Linux systems. It's based on man custom extensions to MOTIF much like SGI's SGM libraries for notebook widgets and non-MOTIF goodies. It runs on many x11 platforms including Xorg and X11Libre as well as forthcoming ports to Tru64 Alpha, and AIX 6.1 on POWER4 or better, and HP-UX 11iv3 Integrity and PA-RISC HP-UX 11.31. There is also a Citrix clone "CyThrough" and a CalDAV desktop calendar, Sunbeam.
Comment Re:The Regime's Numbers (Score 1) 31
The estimate is about $1.8B per day. Which has cost consumers (not businesses) ~$100B thus far.
Submission + - This frog bacterium wiped out cancer tumors in mice with a single dose (sciencedaily.com) 1
fahrbot-bot writes: Science Daily has reported that scientists at the Japan Advanced Institute of Science and Technology (JAIST) have identified a naturally occurring bacterium from the intestines of Japanese tree frogs (Dryophytes japonicus) that demonstrated remarkable anticancer activity in mice. The findings, published in Gut Microbes, introduce a new approach to cancer treatment that uses living bacteria to directly target tumors rather than simply altering the gut microbiome.
In a mouse model of colorectal cancer, a single intravenous dose of E. americana completely eliminated tumors, producing a 100% complete response (CR) rate. The researchers emphasize that these findings are limited to mice, but they believe the results provide an encouraging proof of concept for developing new bacterial cancer therapies.
First, E. americana directly attacks tumors. As a facultative anaerobic bacterium, it thrives in both oxygen rich and oxygen poor environments, allowing it to multiply inside the oxygen deprived regions commonly found within tumors. Once there, the bacterial population increased by roughly 3,000 fold within 24 hours after treatment, directly damaging cancer cells.
Second, the bacterium stimulates the immune system. Its presence attracted T cells, B cells, and neutrophils into tumors. These immune cells then released inflammatory signaling molecules, including TNF- and IFN-, which strengthened the immune response and promoted cancer cell death.
One of the most striking findings was that E. americana accumulated almost exclusively inside tumors and did not colonize healthy organs.
They found that the bacteria were rapidly cleared from the bloodstream, with a half life of approximately 1.2 hours, and became undetectable within 24 hours. No bacterial colonization was detected in healthy organs, including the liver, spleen, lungs, kidneys, or heart.
The treatment caused only mild, temporary inflammation that returned to normal within 72 hours. During a 60 day observation period, the researchers found no evidence of chronic toxicity.
In a mouse model of colorectal cancer, a single intravenous dose of E. americana completely eliminated tumors, producing a 100% complete response (CR) rate. The researchers emphasize that these findings are limited to mice, but they believe the results provide an encouraging proof of concept for developing new bacterial cancer therapies.
First, E. americana directly attacks tumors. As a facultative anaerobic bacterium, it thrives in both oxygen rich and oxygen poor environments, allowing it to multiply inside the oxygen deprived regions commonly found within tumors. Once there, the bacterial population increased by roughly 3,000 fold within 24 hours after treatment, directly damaging cancer cells.
Second, the bacterium stimulates the immune system. Its presence attracted T cells, B cells, and neutrophils into tumors. These immune cells then released inflammatory signaling molecules, including TNF- and IFN-, which strengthened the immune response and promoted cancer cell death.
One of the most striking findings was that E. americana accumulated almost exclusively inside tumors and did not colonize healthy organs.
They found that the bacteria were rapidly cleared from the bloodstream, with a half life of approximately 1.2 hours, and became undetectable within 24 hours. No bacterial colonization was detected in healthy organs, including the liver, spleen, lungs, kidneys, or heart.
The treatment caused only mild, temporary inflammation that returned to normal within 72 hours. During a 60 day observation period, the researchers found no evidence of chronic toxicity.
Comment Just following the Ferengi Rules of Acquisition (Score 1) 109
Rule 99: "Trust is the biggest liability of all."
Comment Re:Fuck I hate how stupid they think we are (Score 2) 102
what did you trade for reliable access to electricity?
The ability to stargaze and an increased probability of burning down my house. How dare they take house burning away from me! It makes me so bad it makes me want to set something one fire... like a house! Wait... OK, so just stargazing.
Comment Re:The cutting edge cuts back. (Score 1) 101
Consoles are usually using out of date hardware by the time of their release.
"usually"? I think you mean post PS3 when they started making x86 based systems. Anyway, designing, testing, and coordinating the construction of millions of these takes time. So sure, "out of date" for children with no grasp of what goes into building hardware, but when the systems are designed, they are cutting edge.
Comment Re: The cutting edge cuts back. (Score 1) 101
it's too expensive to do it fully custom.
Well that sure is funny because everything used to be fully custom.
Comment Re: The cutting edge cuts back. (Score 1) 101
If you're not Nintendo then people expect to be impressed by your graphics - the last Nintendo which fit the bill was the N64
they got burned on N64 because the carts caused the price to be high. However, the lesson they learned was that high-end graphics weren't worth the cost. Literally all of their systems use dated technology. However, they are brilliant when it comes to marketing. Also, they will sue the shit out of you for anything.
