Journal jd's Journal: A question of genetics/epigenetics 3
Genetic Age:
https://www.theguardian.com/science/2022/jun/13/biological-age-startups-why
https://clockfoundation.org/
https://www.mydnage.com/
Whole Genome Sequencing and search engines:
https://nebula.org/
https://www.gedmatch.com/
https://promethease.com/
https://blast.ncbi.nlm.nih.gov/Blast.cgi
Miscellaneous articles:
https://www.today.com/health/do-personalized-diets-work-t183387
https://www.self.com/story/dna-diet
https://www.forbes.com/sites/bernardmarr/2021/02/26/whats-biohacking-all-you-need-to-know-about-the-latest-health-craze/
https://www.webmd.com/vitamins-and-supplements/features/nootropics-smart-drugs-overview
So many tools, so little useful guidance. For example, if you get guidance on diet via a genetics site or a biohacking site, how does that impact your biological age as measured under the Clock Foundation's measures? If at all? If we can objectively test claims, where are the studies showing the experiments?
And if the error bars are too high, then how do we know if the measurements are saying anything at all?
If none of this is known and it's all about doing the experiments, then who is doing those experiments? And what experiments are they doing?
What is epigenetics? (Score:2)
Just read another book with a section on this topic and I'm still skeptical. I think there is something there, but I feel like it may be a confusion between non-causal correlation and patterns that are just artifacts of poking hard enough at too much data... Or maybe my conceptual problem in evolutionary terms is that I can't imagine how the mechanism would work in practice to help organisms survive? The future remains as uncertain as ever...
I think the "question" of your Subject has something to do with ag
Re: What is epigenetics? (Score:2)
In a nutshell, epigenetics seems to be good, old-fashioned parameter passing, or maybe metadata.
The evolutionary benefit is that you only need generic constructs and pass in data that customises it to a problem.
These days, the idea is that your body will make epigenetic adjustments as a response to your environment, tweaking lots of different parameters to fine-tune you.
Aging is the only one anyone currently claims to test for (although we don't know if that is what they measure).
It's also one of the very f
Re: (Score:2)
Interesting way to describe it, but I've read a number of descriptions of epigenetics at similar levels. I should have worded my concern differently. I don't find much of the evidence persuasive. Rather I'm inclined to the view that there's a lot of noise in the genetic signals and they have mined the noise in ways that have led them to think there are some other signals in there.
On the aging topic, the most "persuasive" stuff I've read involves the encoding for rep counts. That actually makes good sense fr