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Comment: Much better article in _Nature_ (Score 5, Informative) 92

http://www.nature.com/news/artificial-spleen-cleans-up-blood-1.15917

Key points:

* The coating on the nanobeads binds to many different things, so it's useful even if you don't know in advance what is making the patient sick.

The device uses a modified version of mannose-binding lectin (MBL), a protein found in humans that binds to sugar molecules on the surfaces of more than 90 different bacteria, viruses and fungi, as well as to the toxins released by dead bacteria that trigger the immune overreaction in sepsis.

* The device can process about 1 litre of blood per hour; compare with about 5 litre blood volume for a typical human, thus this should be able to completely process a person's blood about once every 5 hours. If a faster rate is needed, multiple devices could be used in parallel.

* This has been successfully tested on rats. They infected rats with bacteria and 89% of the rats treated with the "artificial spleen" survived, while only 14% of the control group survived.

* This could move to human clinical trials relatively soon.

Nigel Klein, an infection and immunity expert at University College London, says that the biospleen could also allow diagnosticians to collect samples of a pathogen from the blood and then culture it to identify it and determine what drugs will best treat it. As blood transfusion and filtration are already common practices, he expects that the biospleen could move into human clinical trials within a couple of years.

Read the whole article. It's not long and all of it is interesting.

Comment: Legal precedents (Score 1) 206

by steveha (#47838645) Attached to: Should Cyborgs Have the Same Privacy Rights As Humans?

To decide this, we need to look at the history of the 5th Amendment and how the courts have interpreted it. I'm not a lawyer, but I think it's pretty clear that cyborgs' personal data will be covered.

According to Wikipedia's article on the 5th Amendment, courts have been pretty expansive. You can't even be required to turn over the password to an encrypted hard drive if it would incriminate you.

If I understand the history, the 5th Amendment was partly a backlash over the horribly unfair "Star Chamber" legal proceedings, and also against the use of torture to extract a confession. As a minarchist libertarian, I think it is wise to hold government on a short leash, and I am in favor of keeping the government from taking shortcuts that lead to convictions. But on the other hand, I'm in favor of the truth winning in trials. If you are driving a car and there is a collision, I want experts to be able to examine the "black box" from your car (assuming your car has one); I don't think you can reasonably claim that turning over your "black box" would constitute self-incrimination. So if we imagine a sort of "black box" inside the body of a cyborg, it's hard for me to think that should be private while I think the black box from a car shouldn't be.

Of course, I don't want to see someone have their cyborg body's black box hacked to plant fake evidence against them, but that seems awfully hypothetical at this point.

Hmmm. I wonder if anyone is going to be required to produce the data from their FitBit or other exercise tracker during a criminal investigation anytime soon. I'm guessing that the courts might hold that the 5th Amendment would protect that data. But it would be pretty amazing if you had a guy accused of stabbing someone, and his wrist device had a log showing his hand making stabbing motions at the time the murder occurred!

+ - Google Serves Old Browsers Old Search Page

Submitted by Rambo Tribble
Rambo Tribble (1273454) writes "In an apparent move to push those using older browsers to update, Google is reported to be serving outdated search pages to said browsers. The older pages lack features available on the newer versions, and this policy compounds with the limits announced in 2011 on Gmail support for older web clients. As a Google engineer put it, "We're continually making improvements to Search, so we can only provide limited support for some outdated browsers." The BBC offers a fairly comprehensive analysis, here."

+ - âFakeâ(TM) cellphone towers discovered in U.S.->

Submitted by Anonymous Coward
An anonymous reader writes "Seventeen mysterious cellphone towers have been found in America which look like ordinary towers, and can only be identified by a heavily customized handset built for Android security â" but have a much more malicious purpose, according to Popular Science.

The fake âtowersâ(TM) â" computers which wirelessly attack cellphones via the âoebasebandâ chips built to allow them to communicate with their networks, can eavesdrop and even install spyware, ESD claims. They are a known technology — but the surprise is that they are in active use."

Link to Original Source

Comment: Board games (Score 1) 382

by steveha (#47777423) Attached to: Ask Slashdot: What Are the Best Games To Have In Your Collection?

For group get-togethers, here are some great board games to have on hand.

Can't Stop -- 2 to 4 players. An elegantly simple "push your luck" game. You only need to make one decision: keep going, or stop?
http://boardgamegeek.com/boardgame/41/cant-stop

Incan Gold -- 3 to 8 players. This is a reworked version of a classic called Diamonte. It's another "push your luck" game, but it's very different from Can't Stop in that it's group game. The whole group plays in parallel: they all decide whether to keep going, or stop, and all reveal their choice simultaneously. This means that the 8-player game doesn't really take longer than the 3-player game!
http://boardgamegeek.com/boardgame/37759/incan-gold

I'll second the vote for Pandemic. But if you want something a little simpler than Pandemic, with a less depressing theme, you can play Forbidden Island (2-4 players). Forbidden Island was designed by the same guy who designed Pandemic, and uses many of the same game mechanics. I love the art, which reminds me of Myst; and it is inexpensive and doesn't take up much space in your closet. Very suitable for kids.
http://boardgamegeek.com/boardgame/65244/forbidden-island

All of these suggestions are good for convincing non-gamers to try playing a board game.

P.S. When I was a teenager, some friends and I used to play Wiz-War, and had a blast. It's a simple game: either steal two treasures from other players, or be the last player standing. There is a deck of cards, which includes all kinds of crazy spells you can cast.

Once when I was playing, another player hit me with Slow Death, which makes you lose one hit point for each card you draw; I countered with Reversal, which reverses the effects of a spell, and started drawing two cards each turn (the max). I thought this was a good thing, but the other players were now very worried about me, and they all ganged up on me and just killed me. So the Slow Death worked after all, in a fashion. :-)

The game is now available in a deluxe edition (which I haven't played yet).
http://boardgamegeek.com/boardgame/104710/wiz-war-eighth-edition

Comment: There's something to it (Score 5, Interesting) 281

by steveha (#47752577) Attached to: The Evolution of Diet

I think there is something to the "Paleolithic Diet" idea, but many people are Doing It Wrong.

The prehistoric people exercised all the time, every day. They ate meat when they could get it, which wasn't 100% of the time, and the meat they got was lean. They ate fruit when they could get it, which was almost never (e.g. berries in late summer, a few dried berries other parts of the year). They ate a variety of high-fiber roots, leaves, and other gatherable food. They didn't eat any processed carbs (white flour, white sugar, etc.).

If we lived more like that, we really would be healthier.

But some people take the idea to places I don't think are good. For example, making a "paleo cake" with no processed sugar sounds good, but if it has large amounts of ground nuts and cooked fruit, and is sweetened with maple syrup... it's really not something that the prehistoric people would have eaten and I'm dubious about the benefit.

Also, it is possible for people to adapt to changing conditions in a few generations; it's not necessarily true that evolution works so slowly that the diet from 10,000 years ago is still perfect for us. TFA talked about lactose tolerance in adults. In the cave-man days there was no evolutionary advantage to being able to consume dairy as an adult, but once people started keeping livestock and harvesting dairy, that changed. Now many people can digest lactose as adults.

TL;DR Eat lean protein, complex carbs rather than simple carbs, and get lots of exercise, and you will be healthy.

+ - New Type-C USB connector ready for production->

Submitted by orasio
orasio (188021) writes "One of the most frustrating first world problems ever, trying to connect an upside down Micro-USB connector, is bound to dissappear soon.
Type-C connector for USB is declared ready for production by the USB Promoter Group (http://www.usb.org/press/USB_Type-C_Specification_Announcement_Final.pdf)."

Link to Original Source

Comment: Re:Will AMD APUs ever support ECC RAM? (Score 1) 117

by steveha (#47584557) Attached to: AMD Launches New Higher-End Kaveri APUs A10-7800 and A6-7400K

The socket AM3+ does support ECC (if you choose the right motherboard, ASUS usually do...)

Yeah, I have standardized on Asus for all my builds, and the ECC support is one of the reasons.

If you want ECC for cheap you could buy a lower-end socket AM3+ processor like the FX4350

My most recent build was an FX8xxx part. FX8350 I think.

otherwise Xeon is clearly the better choice.

I have made the choice to not give Intel any of my money if I can help it. I don't like the unethical games Intel plays (example).

Processors are so fast these days anyway, that the difference between the best AMD and the best Intel are not that big a deal for my purposes. And while AMD loses on absolute performance, they generally win on performance-per-money-spent.

Comment: Will AMD APUs ever support ECC RAM? (Score 0) 117

by steveha (#47583469) Attached to: AMD Launches New Higher-End Kaveri APUs A10-7800 and A6-7400K

I have a strong preference for using ECC RAM when I build a new computer.

I would be perfectly happy to use an APU to make a very quiet computer, but the chipsets that support the APUs don't have ECC support.

I admit I'm probably a weird outlier. People who want APUs probably don't want to pay extra for ECC RAM most of the time. Still, will there ever be even one chipset that will add ECC support?

Is there any technical reason why ECC shouldn't be used with an APU?

Comment: Re:GPLv4 - the good public license? (Score 1) 140

by steveha (#47535863) Attached to: The Army Is 3D Printing Warheads

There is an upper bound to how much stuff people will tolerate in a license. If you add even one restriction too many, people will stop using the software at all. If possible, people may fork an older version of the software; if not possible, people will switch to something else, or perhaps start their own project with a different license.

For an example from history, look at what happened to XFree86 when they changed the terms of their license. Pretty much overnight, almost everyone stopped using XFree86 and switched to the then-new X.org project. I'm sure that the XFree86 guys thought that the world would just accept the changes to the license, but that's not what happened; what happened instead is that XFree86 became instantly irrelevant.

So, if RMS takes your advice and adopts the restrictions you propose, some nonzero number of users will fall away, and new forks will begin to appear of the software. Meanwhile the military users will shrug and just deal with it. There is exactly zero chance that your proposed GPLv4 will change the plans of the military, even a little bit.

So now the question becomes: what are you trying to accomplish with your proposed GPLv4? If the benefits outweigh the costs, do it. But do it with full knowledge that there will be costs, and among the costs will be increased fragmentation of open-source software projects (more forks and more new projects).

A CNC machine or a 3D printer can be used to make medical parts, or weapons. It follows that if the military contributes code to control a CNC machine or 3D printer, the contributed code could be used for good purposes. One consequence of your proposed GPLv4 license: code under such a license would no longer receive contributions from the military. Is that part of what you wanted to achieve? I don't see this as a win, myself.

Comment: Re:What a fatuous, nebulous piece of crap??? (Score 1) 161

by steveha (#47496033) Attached to: Microsoft's Missed Opportunities: Memo From 1997

If licensed like DOS, it would have every bit as many compatibility problems.

Oh, not as bad, at least at first. The companies licensing MacOS would have had to make suitable hardware, and Apple could have held their feet to the fire to get compatibility and quality.

In those days, there was so much pent-up demand for Mac laptops that there were companies that would buy a Mac, crack it open and pull out the ROMs, build a laptop with the ROMs, and provide some sort of docking station so the original Mac would not be useless. This was about the most expensive way to make a laptop ever, but it was the only legal way to do it. Apple took forever to release a laptop product, and when they did, it was not what the customers wanted (heavy due to the lead-acid battery for one thing). Third-party Macs could have cost significantly more than generic "beige box" PCs and customers would have paid happily.

The thing is, Apple was charging crazy money for Macs. If Apple had adopted the Microsoft model, they would have had to accept lower margins on each Mac, and made it up on volume. Third-party Macs would have cost less than Apple official Macs but still would have sold a lot and buried the DOS-on-x86 PC. Apple was marking up Macs by about 100%... They were successfully getting a 50% margin on each Mac. Nobody else got away with that kind of markup, before or since.

It was great for Apple while it worked. But eventually Windows got to the point where it was kind of usable. And a Compaq running Windows would cost less than half what Apple was getting for a Mac. Hastings's Law: Adequate and cheaper tends to win against better but more expensive. Windows sales took off and Apple nearly died.

What saved Apple was the PowerBook, a laptop that really was what customers wanted. And a string of other successful products. And now Apple is doing very well. But IMHO, Apple could have had success like Microsoft in the 1990's had they adopted the Microsoft strategy of licensing to everyone and making a small profit on a huge volume; instead they nearly went out of business.

Even now, Apple isn't getting anything close to 50% margins on Macs. Those days are over.

Comment: US and UK "spreading the blame"?? (Score 4, Insightful) 503

by steveha (#47481807) Attached to: Russia Prepares For Internet War Over Malaysian Jet

From the summary:

U.S. and U.K. news organizations are studiously trying to spread the blame

WTF? Is this intended to somehow suggest that the USA and/or UK share some portion of blame?

The article linked in that part of the summary is a CNN article making the case that shoulder-fired missiles cannot reach 33,000 feet, so it must have been military gear. That's it... it even notes that both Russia and the Ukraine have such missiles.

This is news, and a news organization is reporting on it. Go figure. "trying to spread the blame"? "studiously", even! Really?

Comment: Re:What a fatuous, nebulous piece of crap??? (Score 2) 161

by steveha (#47481037) Attached to: Microsoft's Missed Opportunities: Memo From 1997

At the time, discontinuing the licensing of Mac clones was the right thing to do. All they did was tarnish Apple's image.

Actually, I agree with both you and the person to whom you are responding. Apple could have killed Windows by licensing out Mac OS, but it was the wrong thing at the time they actually tried it.

The Microsoft approach was to license out DOS and Windows to anyone who wanted it, taking a small royalty per copy and making money on a huge volume. The Apple approach is to make more money per unit, while selling fewer units. I firmly believe that if Apple had tried the Microsoft approach in, say, 1988, they would have won big-time. Windows was still a joke in 1988, and people were spending crazy money to buy Macs.

Licensing out Mac OS in small volume gains the benefits of neither approach. If Apple only got small volumes, they couldn't make Microsoft levels of money on a small royalty; yet cheap "clones" reduced their ability to charge large amounts on small volumes.

Steve Jobs never wanted the Microsoft approach anyway. He wanted to sell premium stuff that looked awesome and commanded a premium price. But I wish that Apple had embraced the Microsoft model early; we'd all be running Motorola processors rather than x86.

Comment: What I am going to buy (Score 1) 502

I am about to buy an external audio device. To my knowledge, this is the best device you can get for a similar amount of money... you can spend a lot more money to get something about as good, or spend less money and get something worse.

The device is called an O2 amplifier plus ODAC. It was designed by someone who went by the name of "NwAvGuy".

http://spectrum.ieee.org/geek-life/profiles/nwavguy-the-audio-genius-who-vanished

The O2 is a really clean analog amplifier, and is actually open source hardware. You can get the parts list, order the parts yourself, solder everything together, and have your own O2. You can pair it with any DAC, but NwAvGuy also designed a DAC called the ODAC. He(?) said that he would have liked to make the DAC open source as well, but it wasn't practical.

I will buy mine from a company called JDS Labs. They sell a single nice integrated device with O2 and ODAC in one enclosure.

http://www.jdslabs.com/products/48/o2-odac-combo/

There are audiophiles who sneer at the O2 because it doesn't cost enough. At my previous job I spent hours listening to music on an O2 with Sennheiser 650 headphones, and I want to be able to listen to music with that level of quality again. I am willing to spend my own money to do it.

I thought about buying a really nice DAC but I always hesitated to spend the money because it can be hard to figure out what is worth the extra money, and what is just extra expense. I am friends with a world-class audio geek, and he agrees that this is a good quality audio device. If you want top quality and you are spending your own money, get or make an O2.

Comment: How will history judge the F-35? (Score 5, Interesting) 417

by steveha (#47176951) Attached to: Canada Poised To Buy 65 Lockheed Martin F-35 JSFs

Sometimes a new thing looks like a disaster for a while, but in the long run proves itself. The M-16 rifle is a tremendously successful design, but there were issues with the first models that made it look like a huge mistake.

So I am watching the F-35 and I am wondering: will this be as big a disaster as the nay-sayers claim, or will this work out in the long run?

I'm guessing it will limp along as a middle-of-the-road thing: not a complete horrible disaster, just a really expensive airplane that doesn't live up to its expectations.

Also, I have read that it is intended that a bunch of F-35s will share data with each other, and help each other detect and deal with threats; but the giant costs of the program have made it much less likely that enough F-35s will fly together at one time for this to work out.

One thing I am certain about: It's a mistake to try to replace the A-10 Warthog with F-35s. I don't even understand how the F-35 is supposed to do the same mission.

http://www.motherjones.com/mojo/2012/01/a-10-f-35-air-force-budget

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