I had a problem of the screen configuration resetting about a quarter of the time the system went to sleep mode or rebooted. Since upgrading to a newer version of Kubuntu that uses Wayland, I haven't had the issue.
I have a 1440p monitor paired with a weird resolution ultrawide, on a nVidia card. A few months ago I started running 2 GPUs. One monitor I have plugged into the integrated AMD GPU and the other monitor is the the nVidia card.
Wayland handled the weird configuration seamlessly. No problems with drivers. Steam games ran out of the box. I didn't have to even set the resolution if I recall. Maybe it's not fair to attribute this to Wayland, but I've used X11 on and off for 20 years, and had a lot more problems with it.