You're right about YouTube. I was thinking HEVC was one of their delivery formats, but apparently not.

Netflix definitely did use HEVC for delivery of some of its high-end content at one time. Whether they still do or not, I have no idea.

Either way, the fact that people are running into error messages suggests that there is some actual customer impact.

Except that nobody who buys one of their machines is going to think, "I could pay an extra $100 and my machine would work better." They're going to think, "This piece of s**t can't even do things that my cell phone from eight years ago can do. Why did I buy this, and why should I ever buy anything from this manufacturer in the future?"

This level of penny-wise, pound-foolish behavior is a sure way to permanently lose customers.

...or decoding...

You mean like... anyone who wants to watch Netflix or YouTube or any other streaming service's high-res content?

When I see things like "facial age verification", I have major concerns, whether we're talking about a site like Roblox (whatever that is — I don't know, and don't really care), social media, porn, or any other site. How are you going to do it without violating the privacy of every person who creates an account? And how are you going to verify that the person using the account is the person who created it without causing an even bigger privacy violation?

We do need some sort of age verification system, but we need it to be designed in a way that protects privacy. I have less than zero faith in any individual website to come up with such a system, and approximately zero faith in any individual government to do so. There really needs to be an international age verification working group that spends the next five years coming up with a system, then pressures everyone to implement it.

Doing it the other way around, with companies or governments shoveling bad, partial, or even dangerous solutions to the problem down everyone's throats, can only result in greater levels of push-back by the general public towards a proper scheme if someone ever creates it.

They did review and change the policy. Just too late to do any good. The point is that evidence-based medicine has to be treated as a starting point for diagnosis and treatment decisions, not a rigid decision tree.

Of course, none of that makes the CDC's new claims that "vaccines don't cause autism" isn't an evidence-based statement any less absurd. You can't ever realistically prove definitively that X cannot cause Y, because that would require knowing that there exists no combination of recognizable human genetics in which X would cause Y. Evidence-based medicine would mean assuming that X cannot cause Y until evidence exists to prove that it does or can, which has not happened.

What they're doing is rejecting evidence-based medicine based on a belief that the anecdotal information they have should be taken more seriously than the broad evidence to the contrary. This would be fine if that anecdotal information were based on actual brain scans prior to vaccination that showed that the vaccine triggered a change, but it isn't. Rather, involves mistaking correlation for causation, and a post hoc ergo propter hoc fallacy, with a complete lack of any actual plausible explanation for how vaccines could cause autism beyond some vague hand-wavey pseudoscience.

And on top of that, we have a bunch of people who lack enough understanding of the scientific method and/or lack enough understanding of the subject to recognize when it is not being followed properly, and they are getting misled by charlatans with a political or personal agenda, presented in the form of pseudoscientific bulls**t papers that don't hold up to even modest scrutiny by someone with limited understanding of the subject or the scientific method, much less actual scientists in the field.

We also have a bunch of journals that publish papers outside their area of expertise, relying on outside experts that are in league with the papers' authors, and all sorts of other fun scientific fraud, which further contributes to this problem.

I'm not sure how to solve this problem, because it seems like a large percentage of the public simply lacks basic critical thinking skills and the ability to read over a paper and think, "Yes, but did you consider the following twelve common factors that could influence both the proposed cause and effect?" and realize that the paper is garbage. But a good starting point would be to pressure the news media across the political spectrum to hire actual science writers who UNDERSTAND SCIENCE to cover science-based stories.

Another good starting point would be to get more science-based shows on PBS that can talk about these issues and explain them to people and debunk bulls**t every week.

Unfortunately, evidence-based medicine has become a code word for "treat everyone with the same illness identically even when the data doesn't support doing so. That's how I ended up fighting a c. diff. infection. I was hospitalized for a related condition, and the first day of antibiotics put me at no fever, but after a day, I got a fever again, and I asked if the antibiotic had changed, and they said no, but maybe the ER gave me something different. They checked, and determined that yes, I had been on a different antibiotic in the ER, but said that they should keep the current antibiotics, and used "evidence-based medicine" as the reason. I had my doubts.

They were wrong. And six months later, the general standards for treating the condition I came in with changed, and they now treat it with the antibiotic that the ER gave me instead of one of the two that the hospital put me on afterwards, precisely because the standard treatment had a tendency to make c. diff. take over.

Whoops.

So I'm all for evidence-based medicine as a starting point, but when you realize it isn't behaving normally, you should adjust accordingly. Otherwise, patients suffer enormously.

But in theory, I do agree with you that evidence-based medicine is better than evidence-free medicine based on gut feelings and assumptions that correlation means causation and other fallacious reasoning.

When Google sells a 24-inch tablet, I'll care about Google being able to sell me a replacement that can do this. In the meantime, I want this feature on older, non-Google Android devices. :-)

Actually, I was remembering wrong there. Although TB can spread in other ways, it is primarily an airborne pathogen. So the biggest way to reduce the spread would be to add central heat and air with fresh air mixing and reduce the number of people sharing air for long periods of time. The second best way is contact tracing and prophylactic treatment.

But to add further to the comment about vaccine effectiveness, bacterial vaccines can be at least somewhat effective at preventing disease, e.g. the bacterial meningitis vaccine has something like 65% to 85% effectiveness, depending on age group and other factors, which is way better than nothing.

The TB vaccine only reduces infection risk by 20%. And when you're exposed frequently, that's barely even useful. The reason for this is that it hides from the immune system, which, as a result, takes a long time to start reacting to the bacteria, allowing it time to multiply for a while before you get a reaction. In mouse models, the reaction takes a whopping two weeks.

TB actually infects macrophages (primitive immune cells), and manages to literally hide inside them by adapting its exterior to maintain a neutral pH and by synthesizing enzymes that prevent the macrophages from maturing and that slow down apoptosis, which otherwise would release the bacteria, which would trigger T-cell activation. It's unclear whether there is a realistic way to prevent this delay.

It also plays tricks like triggering certain antigen-specific CD4+ T cells to the point of functional exhaustion while reducing antigens that would trigger other CD4+ cells so that they don't get detected. It somehow brings mesenchymal stem cells (blood vessel/lymphatic/connective tissue precursors) to the infection site, which further inhibit stem cells.

Presumably any better vaccine would have to either convince CD8+ T cells to react even without macrophages recognizing that something is wrong (perhaps by increasing the number of antigens that are included so that they are more likely to recognizing an antigen on the bacterium itself directly, early in the infection process, assuming this is even possible), convince CD4+ T cells to trigger macrophages in spite of signals to not do so, or overcome one of the design limits of the immune system (preventing T-cell exhaustion, increasing random macrophage apoptosis without an infection, etc.), some of which would likely require changing the person's DNA.

So fast diagnosis (universal health care and widespread rapid TB testing), contact tracing, etc. are critical to bringing it under control, and other prevention, such as not having large numbers of people in constant contact in areas with limited air circulation can also help. Meanwhile, vaccines, although not entirely infeasible, are likely to be more of a long shot.

"It's my estimation that every man ever got a statue made of him was one kind of a son of a bitch or another." --Malcolm Reynolds

(Ironically applies well to Joss Whedon himself. Kind of wonder if one of the show writers was thinking about Joss when they wrote that...)

The only single-source point of failure is me.

...over 143 years, 46 of which were before the discovery of the first antibiotic.

over six years, all but about one of which were post-vaccine. These two diseases are not really comparable in any meaningful way.

About 1.23 million people die from TB in a typical year, which is not that far off from the worldwide COVID death toll each year. We're mostly not talking about COVID anymore, either.

Vaccines for bacteria are... problematic at best, because they have relatively low effectiveness at preventing infection. The best way to eliminate TB is to get clean water everywhere. Stopping TB through vaccination is like stopping pedestrian deaths with inflatable pedestrian balls. Yeah, it might reduce the mortality, but the real problem is unsafe pedestrian crossings / unsafe drinking water.

We don't, though the laws of supply and demand pretty much dictate that there must be some equilibrium point beyond which people buy fewer tickets and they end up losing money on non-refundable tickets.

Note that I'm not suggesting that raising prices is the right solution. It's a terrible solution.

Which in a free market indicates that the price is below what the market would bear. Otherwise, they would be unable to make a profit by reselling them. So the GP is not wrong, at least from a pure price optimization perspective.

This is not to say that there aren't societal benefits from charging less than the market will bear, of course, nor saying that scalping in any way adds value. It is basically rent seeking behavior, which makes it a drain on society. But the point still remains that obviously the ticket vendors could raise the prices to what the scalpers were charging and still sell tickets. Whether the scalpers would then be able to raise their prices further is unknown.

I think I saw someone swimming in some sewage en route from scraping a bear carcass off the road, let me go check.

1. I got asked once if I played world of warcraft since they say a guy with the name "thegarbz" playing. I said no. By the way I know exactly who that person is because he impersonated me as a joke. I found that flattering and funny, but it has no impact on my life beyond that.

Reminds me of my first email account ;) One of my professors said we all had to register for an email account (this was in the mid-90s) so we could submit our homework to him, so I registered his name at hotmail.com to mess with him ;)