Let's hope it goes better than BillG school reform!
It won't. Bill suffers from the same ego problem that many successful people suffer from - thinking that because you were good at one thing means you are qualified to solving every other problem. But very few people are great in vastly different domains. Even most geniuses stick to at least one area.
Giving money to people who are real experts in a domain and giving them room to find solutions is a hundred times better than coming in as a celebrity and taking over with your own random idea. This can, in fact, have a negative effect on the actual progress in the field.