Comment Favorite blah blah (Score 2) 321
Who cares? Let's just post big lists of web comics so we can all click and read and woohooooo!
Beyond the obvious (XKCD, Penny Arcade, Dilbert, The Oatmeal) there are at least these:
http://amultiverse.com/
http://www.virtualshackles.com/
http://www.cad-comic.com/cad/
http://www.escapistmagazine.com/articles/view/comics/critical-miss.latest
http://chainsawsuit.com/
http://dresdencodak.com/archives/
http://www.happletea.com/
http://questionablecontent.net/view.php?comic=2347