Feed Science Daily: Colon Cancer A Disease Of Hormone Deficiency, Scientists Suggest (sciencedaily.com)
Researchers have found new evidence suggesting that colon cancer is a disease of missing hormones that could potentially be treated by hormone replacement therapy. Early in colon cancer development, two intestinal cell growth-controlling hormones are "lost," disrupting the activity of the hormones' receptor, GCC. Using two mouse models of colon cancer development in people, the scientists showed that GCC signaling blocks tumors from forming, meaning that colon cancer could be a disease of hormone insufficiency.