We don't know how much 1/6 gravity redresses these problems.
I gotta admit, this is something that annoys me.
When the ISS was first started, one of the modules was going to contain a set of centrifuges for experiments on different amounts of G forces. You could stick mice in there and have them live for 6 months in 1/6G or 1/8G or 1G or 2G or whatever and see what issues they had. It never got off the ground. So all we can do is sit around and go, "Gosh, I don't know how we'll react in different G levels."
Which seems kind of important.
First, for travel. If we're going to have some sort of spinning thing to create "artificial gravity", how fast does it need to spin? Do we need 1G? Can we get by with 0.5G? Do we need to spend all our time in 1G? Can we, say, sleep in 1G for eight hours and work in 0G for 16 hours? Or vice-versa? How would that affect the design of spacecraft, if we had a zero G bunkhouse and 1G working environment (versus having to have room for beds and the working environment all spinning around)
Second, for long-term habitation. Working in a shirt-sleeve environment in 1/6G might be a problem. The solution, though, might be to walk around in a 1000 lb. (on Earth) spacesuit for a few hours. But, again, just because your muscles are getting the workout doesn't mean your heart is necessarily having to work as hard to pump blood in 1/6G. How does that affect things?
We had a lab ready to go to at least try to figure some of that stuff out. Let's get that up there while we still have an ISS where we can research this stuff...