I installed in on my HP ProBook 6475b laptop the other day and have only run into some minor issues.
1. I opted for full disk encrypted LVM. It didn't ask for a separate Swap partition password, instead using the main one. Fine. However, when booting, I have to enter it twice -- once for the main partition, once for swap. [Bug reported and acknowledged]
2. It hangs on reboot. I have to boot twice every time to get it to get past the boot loader. I've tried "shut down", then letting it sit for 10 minutes. Next boot -- hang and I reboot and then it works.
3. My wifi doesn't come back after suspend. I think it has to do with the particular laptop firmware, because it does this with every distro I've tried. Everything else works, but the wifi never makes it out of suspend.
The rest works fine. Changing to the proprietary AMD video drivers was a snap, and it sped up video playback to what I would expect (no stuttering on HD).