A shootout with an autodrive car. Sure the criminal could have the car driving to a destination while they hang out the window and shoot. Of course, the car would go the legal speed, stop at all lights and stop signs, and generally be much safer than any car driven by a human, much less one shooting or getting shot at.
Not to mention it will probably have a police override allowing them to remotely either stop it, or redirect it to a place of their choosing. I wouldn't be surprised if it would even tell the police it's intended route and destination if they asked it.
It will also probably have an emergency responder reaction where if there are sirens from police, fire, or ambulance it pulls over to the side and stops, as that is the law for humans. And as the poster mentioned, a partner could always drive a car so the one riding shotgun could still shoot.
Using it for bombings. What's so different from sending an autodrive vehicle to someplace with a bomb in it as opposed to sending a regular vehicle with a bomb and then leaving it before it blows, or even having some ignorant stooge drive it for you? After all, it's not like you can make the autodrive violate it's programming and plow through a crowd or into a mall. If you really wanted to do that, you could just rig a normal car up with remote controls. It's not that hard or expensive, they do it a lot on mythbusters, so it's not a strange concept to most people either.
Of course, the FBI has way too many people that need to deal with technology that really don't understand it in the slightest. Years ago I had to disappoint an FBI agent that I was helping by explaining to him how things really worked. He was getting samples from all the different printers so that they could make a database to identify what printer printed something like they used to do with typewriters. I had to explain to him that the fonts are totally programmable and have no unique characteristics to that printer. Also, that the inks and toners are actually made by only a handful of companies, and are again, not unique to the printer. He was very disappointing with the information.