The nice thing about this one, since it is yeast based, it is good to take with antibiotics, if you need to take them.
My wife has long term digestive issues from celiac disease - she's been gluten free for more than 4 decades. This has also helped that - she still doesn't eat gluten, of course, since this doesn't change one's genetics, but she has fewer other issues. I take it too -- and I told a friend of mine who had pretty serious IBS and she told me that one capsule daily (they suggest to take 2) got her off her several hundred dollars per month prescription med because her symptoms went away. Obviously this is one case, but I was really glad for her. But it seems to have pretty far ranging effects. As I understand it, this was the first probiotic discovered, in France, reasonably early in the 20th century. But do not quote me on this.