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Comment Experience (Score 1, Insightful) 155

In a yellow cab, you have to deal with often times 25 year old vehicles in poor condition, the dispatcher blaring on the radio the whole ride. You can call a cab, and there is no guarantee one will show up, and not to mention the tip you're expected to bestow. In Uber... you get a new, higher end black car or SUV and you don't have to tip, the cars have always been clean... and unless you were one of the handful of well publicized incidents... the experience is much more classy and high end then an old yellow cab. You get what you pay for.

Comment Keep a structured routine (Score 3, Interesting) 480

Once upon a time I WFH'd for ~ 5 years with occasional travel and trips into the office. I was home alone all day with no one to distract me but myself. I increased my satisfaction and productivity by identifying and correcting some bad habits I developed early on. I suggest you keep a routine you are comfortable with and try to stick to it. Try to do the things you would do if you were going to head into the office and be face to face with people. Simple things like waking up to an alarm, brushing your teeth, shaving, showering, getting out of the pajamas all before starting work at a set time. Instituting that type of structure allowed me stop taking conference calls in my underwear with a 3 day beard, stinking to high hell with a bowl of Cap'n Crunch. By getting ready for work, I felt like I was respecting the job and my responsibilities by not anonymously being a slob. (Not that I don't long for those days in my current role.... M-F 9-6 Shirt and tie) -Gregg
Medicine

Dissecting the Neural Circuitry of Fear 123

al0ha writes "Fear begins in your brain, and it is there — specifically in an almond-shaped structure called the amygdala — that it is controlled, processed, and let out of the gate to kick off the rest of the fear response. In this week's issue of the journal Nature, a research team led by scientists at the California Institute of Technology has taken an important step toward understanding just how this kickoff occurs by beginning to dissect the neural circuitry of fear. In their paper (abstract), these scientists ... describe a microcircuit in the amygdala that controls, or 'gates,' the outflow of fear from that region of the brain. The microcircuit in question, [Professor David J. Anderson] explains, contains two subtypes of neurons that are antagonistic — have opposing functions — and that control the level of fear output from the amygdala by acting like a seesaw. 'Imagine that one end of a seesaw is weighted and normally sits on a garden hose, preventing water — in this analogy, the fear impulse — from flowing through it,' says Anderson. 'When a signal that triggers a fear response arrives, it presses down on the opposite end of the seesaw, lifting the first end off the hose and allowing fear, like water, to flow.' Once the flow of fear has begun, that impulse can be transmitted to other regions of the brain that control fearful behavior, such as freezing in place."

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