Drug tests occur in an area where mistakes can ruin a company through lawsuits. I think the reliability there is far above average. That is, reliability where health hazards are concerned. I would not be so sure about effectivity testing but I still suspect that this more visible area of science is one where experimental rigor is way above average. I may be a sceptic about what average means.
Finding out whether your medicine will hurt someone in thirty years time can be pretty hard. Failing to do so doesn't mean you couldn't be bothered.