I've had it running since yesterday
-Unobtrusive
-Caught 4 virii (keylogger & trojans)missed by ESET NOD32 in software installers I had downloaded
-Took about 40% longer to do a full deep scan than Nod32
-No logs showing that the scans ran when scheduled (only a list of detected problems)
-Smart enough to look for virus catalog updates right before scanning
-Phones home to MSFT (anonymously) with security data
It seems less obtrusive running in the background watching applications & downloads than Norton 2009 did on my old computer. I haven't tried Norton 2010 (and hopefully never will)
I found ESET Smart Security 4 to be buggy on Win 7 x64 (dropping the internet connection unless I disabled the firewall mini-driver)
Overall, this Windows Security Essentials seems like the best option for me right now. And it's free, which is nice.