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Comment Re:test drive? (Score 1) 238

People's attitudes about cars are so strange. LOTS of people get injured in car accidents to the point where they can't use a phone to call for help. As the OP stated, these systems are mandatory now in Europe so lots of people "give [enough of] a fuck to own [them]."

Anyway, my comment was about your reading comprehension. You excoriated the OP for "i can't see how you'd imagine someone wouldn't want to disable it" when what they said was they couldn't imagine why someone would want to buy their own after disabling the built in one.

You sound like an old dude. Highways were deathtraps back in the days of "a time when people used CBs and ham radios with autopatch for automotive emergencies." You've got your fondly remembering your life glasses on and they're interfering with your ability to read and making you say dumb stuff.

Comment Re:NPR lost the plot on this article (Score 1) 53

There is minuscule public (non-insider) information about medical trials.

Typically there's quite a bit. "New" drugs usually have quite a bit of published pre-clinical work, sometimes going back decades, and previous phase clinical trials must be published.

This is "gambling".

Yes. All all the justifications Kalshi came up with are bullshit. Either things that already exist in a non-gambling form (e.g. clinicaltrials.gov) or are not useful.

Comment Re:But...they share the same DNA building blocks (Score 2) 104

The canonical RNA bases are conserved between branches of life, but the modified versions vary quite a bit, and quite a few of them are kingdom-specific. Substituting pseudouridine isn't something we invented, for example, it's pretty common in archea.

The DNA bases seem to be universal. We've created synthetic base pairs that seem to work okay, but we're also just barely starting to build the first beginnings of a metabolism on them so we're a long way from showing that they do more than pair up appropriately.

Anyway, the story is about metabolism rather than genetic code. The summary is dumb.

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