Transitioning from unix to Windows automation

Zubinix writes: I have a background in doing automation in a unix/linux environment using scripting languages such as perl and bash shell, as well as ssh for remote scripting. My next project will be in the Windows environment so what approach and methodology is best for developing say the automation required for a test system? I don't want to use things like cygwin as I need to integrate with Windows applications such as exchange and sharepoint. Is there a list of should and should not do's when it comes to Windows automation?